Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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A 32-year-old man with plexiform schwannoma of the thyroid gland: a case report

  • Il Rae Park (Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Min Chong Kim (Department of Pathology, Yeungnam University College of Medicine) ;
  • Seung Min Chung (Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeungnam University College of Medicine) ;
  • Si Youn Song (Department of Otorhinolaryngology-Head and Neck Surgery, Yeungnam University College of Medicine)
  • Received : 2024.06.05
  • Accepted : 2024.08.19
  • Published : 2024.10.31
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Abstract

Plexiform schwannomas representing a rare subset, comprise 5% of all schwannomas. However, their occurrence in the thyroid gland is exceptionally rare. A 32-year-old male presented with an incidentally discovered, asymptomatic thyroid mass. Imaging revealed an approximately 5 cm heterogeneous solid mass on the right thyroid lobe extending to the upper mediastinum and directly invading the upper trachea. Under the suspicion of thyroid malignancy, the patient underwent right thyroidectomy. Histological examination confirmed a plexiform schwannoma with S100-positive spindle cells. Currently, the patient is undergoing outpatient follow-up, with no reported complications. To our knowledge, this is the first documented case of plexiform schwannoma of the thyroid gland within the English literature. This case highlights the diverse and unpredictable clinical manifestations of thyroid masses, emphasizing the importance of a multidisciplinary approach for diagnosing and managing rare entities, such as thyroid gland schwannomas.

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References

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