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Absorbable versus Nonabsorbable Sutures for Facial Skin Closure: A Systematic Review and Meta-analysis of Clinical and Aesthetic Outcomes

  • Kashish Malhotra (Department of Surgery, Dayanand Medical College and Hospital) ;
  • Sophie Bondje (Department of ENT Surgery & Cancer Services, Torbay Hospital) ;
  • Alexandros Sklavounos (Urology Division, Department of Surgery, Addenbrooke's Hospital, University of Cambridge) ;
  • Hatan Mortada (Division of Plastic Surgery, Department of Surgery, King Saud University Medical City, King Saud University) ;
  • Ankur Khajuria (Department of Surgery & Cancer, Imperial College London)
  • Received : 2023.06.05
  • Accepted : 2024.04.15
  • Published : 2024.07.15

Abstract

When repairing facial wounds, it is crucial to possess a thorough understanding of suitable suture materials and their evidence base. The absence of high-quality and comprehensive systematic reviews poses challenges in making informed decisions. In this study, we conducted a review of the existing literature and assessed the quality of the current evidence pertaining to the clinical, aesthetic, and patient-reported outcomes associated with absorbable and nonabsorbable sutures for facial skin closure. The study was registered on Prospective Register of Systematic Reviews. We conducted searches on Embase, Ovid, and PubMed/MEDLINE databases. Only randomized controlled trials (RCTs) were eligible for inclusion in this study. Additionally, the risk of bias in the randomized studies was assessed using Cochrane's Risk of Bias Tool. The study included a total of nine RCTs involving 804 participants with facial injuries. Among these injuries, absorbable sutures were utilized in 50.2% (403 injuries), while nonabsorbable sutures were employed in 49.8% (401 injuries). The analysis of cosmesis scales revealed no statistically significant difference between absorbable and nonabsorbable sutures regarding infections (p = 0.72), visual analog scale (p = 0.69), wound dehiscence (p = 0.08), and scarring (p = 0.46). The quality of the included studies was determined to have a low risk of bias. Absorbable sutures can be considered a suitable alternative to nonabsorbable sutures, as they demonstrate comparable aesthetic and clinical outcomes. Future high-quality studies with a level I evidence design and cost-effectiveness analysis are necessary to enhance clinician–patient shared decision-making and optimize the selection of suture materials. Level of evidence is I, risk/prognostic study.

Keywords

References

  1. Guo S, Dipietro LA. Factors affecting wound healing. J Dent Res 2010;89(03):219-229 
  2. Braun TL, Maricevich RS. Soft tissue management in facial trauma. Semin Plast Surg 2017;31(02):73-79 
  3. Rose J, Tuma F. Sutures and Needles. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020. Accessed September 1, 2022 at: https://www.ncbi.nlm.nih.gov/books/NBK539891/ 
  4. Fowler JR, Perkins TA, Buttaro BA, Truant AL. Bacteria adhere less to barbed monofilament than braided sutures in a contaminated wound model. Clin Orthop Relat Res 2013;471(02):665-671 
  5. Moy RL, Waldman B, Hein DW. A review of sutures and suturing techniques. J Dermatol Surg Oncol 1992;18(09):785-795 
  6. Fein JA, Zempsky WT, Cravero JPCommittee on Pediatric Emergency Medicine and Section on Anesthesiology and Pain Medicine American Academy of Pediatrics. Relief of pain and anxiety in pediatric patients in emergency medical systems. Pediatrics 2012;130(05):e1391-e1405 
  7. Wade RG,Wormald JC, Figus A. Absorbable versus non-absorbable sutures for skin closure after carpal tunnel decompression surgery. Cochrane Database Syst Rev 2018;2(02):CD011757 
  8. Gillanders SL, Anderson S, Mellon L, Heskin L. A systematic review and meta-analysis: do absorbable or non-absorbable suture materials differ in cosmetic outcomes in patients requiring primary closure of facial wounds? J Plast Reconstr Aesthet Surg 2018;71(12):1682-1692 
  9. Al-Mubarak L, Al-Haddab M. Cutaneous wound closure materials: an overview and update. J Cutan Aesthet Surg 2013;6(04):178-188 
  10. Fosko SW, Heap D. Surgical pearl: an economical means of skin closure with absorbable suture. J Am Acad Dermatol 1998;39(2 Pt 1):248-250 
  11. Moher D, Liberati A, Tetzlaff J, Altman DGPRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009;151(04):264-269, W64 
  12. Cumpston M, Li T, Page MJ, et al. Updated guidance for trusted systematic reviews: a new edition of the Cochrane Handbook for Systematic Reviews of Interventions. Cochrane Database Syst Rev 2019;10(10):ED000142 
  13. Schiavo JH. PROSPERO: An international register of systematic review protocols. Med Ref Serv Q 2019;38(02):171-180 
  14. Higgins JP, Altman DG, Gotzsche PC, et al; Cochrane Bias Methods Group Cochrane Statistical Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ 2011;343:d5928 
  15. Sullivan D, Chung KC, Eaves FF III, Rohrich RJ. The level of evidence pyramid: indicating levels of evidence in Plastic and Reconstructive Surgery articles. Plast Reconstr Surg 2011;128(01):311-314 
  16. Parell GJ, Becker GD. Comparison of absorbable with nonabsorbable sutures in closure of facial skin wounds. Arch Facial Plast Surg 2003;5(06):488-490 
  17. Karounis H, Gouin S, Eisman H, Chalut D, Pelletier H, Williams B. A randomized, controlled trial comparing long-term cosmetic outcomes of traumatic pediatric lacerations repaired with absorbable plain gut versus nonabsorbable nylon sutures. Acad Emerg Med 2004;11(07):730-735 
  18. Holger JS, Wandersee SC, Hale DB. Cosmetic outcomes of facial lacerations repaired with tissue-adhesive, absorbable, and nonabsorbable sutures. Am J Emerg Med 2004;22(04):254-257 
  19. Rosenzweig LB, Abdelmalek M, Ho J, Hruza GJ. Equal cosmetic outcomes with 5-0 poliglecaprone-25 versus 6-0 polypropylene for superficial closures. Dermatol Surg 2010;36(07):1126-1129 
  20. Luck R, Tredway T, Gerard J, Eyal D, Krug L, Flood R. Comparison of cosmetic outcomes of absorbable versus nonabsorbable sutures in pediatric facial lacerations. Pediatr Emerg Care 2013;29(06):691-695 
  21. Eisen DB, Zhuang AR, Hasan A, Sharon VR, Bang H, Crispin MK. 5-0 Polypropylene versus 5-0 fast absorbing plain gut for cutaneous wound closure: a randomized evaluator blind trial. Arch Dermatol Res 2020;312(03):179-185 
  22. Erol O, Buyuklu F, Koycu A, Jafarov S, Gultekin G, Erbek SS. Comparison of rapid absorbable sutures with nonabsorbable sutures in closing transcolumellar incision in septorhinoplasty: short-term outcomes. Aesthetic Plast Surg 2020;44(05):1759-1765 
  23. Moran B, Humphrey S, Seal A, Berkowitz J, Zloty D. Photographic assessment of postsurgical facial scars epidermally sutured with rapidly absorbable polyglactin 910 or nylon: a randomized clinical trial. J Am Acad Dermatol 2020;83(05):1395-1399 
  24. Luck RP, Flood R, Eyal D, Saludades J, Hayes C, Gaughan J. Cosmetic outcomes of absorbable versus nonabsorbable sutures in pediatric facial lacerations. Pediatr Emerg Care 2008;24(03):137-142 
  25. Sajid MS, McFall MR, Whitehouse PA, Sains PS. Systematic review of absorbable vs non-absorbable sutures used for the closure of surgical incisions. World J Gastrointest Surg 2014;6(12):241-247 
  26. Xu B, Xu B, Wang L, et al. Absorbable versus nonabsorbable sutures for skin closure: a meta-analysis of randomized controlled trials. Ann Plast Surg 2016;76(05):598-606