Clinical and Experimental Vaccine Research

The Korean Vaccine Society (대한백신학회)
권호 표지
DOI QR코드

DOI QR Code

Urinary incontinence after COVID-19 vaccination: a case study in an 8-year-old boy

  • Thi Loi Dao (Thai Binh University of Medicine and Pharmacy) ;
  • Trung Kien Nguyen (Thai Binh University of Medicine and Pharmacy) ;
  • Xuan Bai Nguyen (Thai Binh University of Medicine and Pharmacy) ;
  • Kieu Dung Le (Thai Binh University of Medicine and Pharmacy) ;
  • Khanh Linh Duong (Thai Binh University of Medicine and Pharmacy) ;
  • Duc Manh Bui (Thai Binh University of Medicine and Pharmacy) ;
  • Cam Anh Nguyen Le (Thai Binh University of Medicine and Pharmacy) ;
  • Van Thuan Hoang (Thai Binh University of Medicine and Pharmacy)
  • Received : 2024.03.08
  • Accepted : 2024.06.29
  • Published : 2024.07.31
Download PDF
⟨ Previous Next ⟩

Abstract

There have been many studies on the adverse effects of coronavirus disease 2019 (COVID-19) vaccines but the urinary incontinence after COVID-19 vaccination is rare. Here, we report an 8-year-old boy presented to outpatient department, Thai Binh University of Medicine Hospital, Thai Binh, Vietnam with complaints of urinary incontinence for the past 2 weeks, following the first dose of the messenger RNA vaccine. He had no other abnormalities in clinical and laboratory exams. This clinical situation suggested vaccine side effects. No specific treatment was administered upon diagnosis without toilet and bladder training. Subsequent monitoring revealed a gradual reduction in symptoms over 2 months, with complete recovery achieved at the 14th week from the onset of symptoms, without necessitating any medical intervention. This case highlights the need for thorough evaluation and assessment of potential adverse effects following vaccination, including uncommon presentations.

Keywords

Acknowledgement

We would like to thank the medical staff in Thai Binh University of Medicine Hospital for their help in data collection.

References

  1. Nicola M, Alsafi Z, Sohrabi C, et al. The socio-economic implications of the coronavirus pandemic (COVID-19): a review. Int J Surg 2020;78:185-93.
  2. Kashte S, Gulbake A, El-Amin Iii SF, Gupta A. COVID-19 vaccines: rapid development, implications, challenges and future prospects. Hum Cell 2021;34:711-33.
  3. United States Food and Drug Administration. FDA takes key action in fight against COVID-19 by issuing emergency use authorization for first COVID-19 vaccine [Internet]. Silver Spring (MD): United States Food and Drug Administration; 2020 [cited 2024 Feb 23]. Available from: https://www.fda.gov/news-events/press-announcements/fda-takes-key-action-fight-against-covid-19-issuing-emergency-use-authorization-first-covid-19
  4. Walter EB, Talaat KR, Sabharwal C, et al. Evaluation of the BNT162b2 COVID-19 vaccine in children 5 to 11 years of age. N Engl J Med 2022;386:35-46.
  5. Yaamika H, Muralidas D, Elumalai K. Review of adverse events associated with COVID-19 vaccines, highlighting their frequencies and reported cases. J Taibah Univ Med Sci 2023;18:1646-61.
  6. Dhar N, Dhar S, Timar R, Lucas S, Lamb LE, Chancellor MB. De novo urinary symptoms associated with COVID-19: COVID-19-associated cystitis. J Clin Med Res 2020;12:681-2.
  7. Letchuman V, Wemhoff KM, Gandhoke GS. Acute inflammatory demyelinating polyneuropathy with bowel and bladder incontinence following COVID-19 infection. Cureus 2021;13:e17896.
  8. Emordi V, Lo A, Bisharat M, Malakounides G. COVID-19-induced bladder and bowel incontinence: a hidden morbidity? Clin Pediatr (Phila) 2024;63:10-3.
  9. Chen YC, Liang YC, Ho SJ, et al. Does COVID-19 vaccination cause storage lower urinary tract symptoms? J Clin Med 2022;11:2736.
  10. Tran LN, Puckett Y. Urinary incontinence. Treasure Island (FL): StatPearls Publishing; 2023.
  11. Daryanto B, Janardhana A, Purnomo AF. The effect of COVID-19 severity on lower urinary tract symptoms manifestations. Med Arch 2022;76:127-30.
  12. Rabail R, Ahmed W, Ilyas M, et al. The side effects and adverse clinical cases reported after COVID-19 immunization. Vaccines (Basel) 2022;10:488.