Clinical Nutrition Research

The Korean Society of Clinical Nutrition (한국임상영양학회)
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The Association of Serum Vitamin D With Anthropometric Indices, Lipid Profile, ICAM-1, and IL-17 in Patients Undergoing Coronary Artery Bypass Graft Surgery

  • Nazanin Tafteh (Student Research Committee, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences) ;
  • Shahab Rezaeian (Infectious Diseases Research Center, Health Institute, Kermanshah University of Medical Sciences) ;
  • Hadi Abdollahzad (Department of Nutrition, School of Medicine, Urmia University of Medical Sciences) ;
  • Feridoun Sabzi (Department of General Surgery, School of Medicine, Kermanshah University of Medical Sciences)
  • Received : 2024.06.26
  • Accepted : 2024.07.23
  • Published : 2024.07.31
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Abstract

This study aimed to assess the relationship between serum levels of vitamin D with anthropometric indices, lipid profile and vascular inflammatory factors, in patients who candidate for coronary artery bypass grafting (CABG). This analytical cross-sectional study was conducted in patients who were candidate for CABG. Demographic information, medical records, anthropometric indicators, blood samples, and physical activity of 150 patients were collected. 146 participants with mean ± standard deviation of age: 61.8 ± 10.0 years and body mass index: 26.9 ± 3.7 kg/m2 completed the study. Based on serum levels of vitamin D, patients were divided into 2 groups; groups with sufficient (≥ 30 ng/mL) and insufficient amount of vitamin D (< 30 ng/mL). The 30.14% of the patients had serum vitamin D deficiency. Ejection fraction (EF) % between the 2 groups had significant difference. Unexpectedly the EF% increased 7% in patients with insufficient level of vitamin D (odds ratio [OR], 1.07; 95% confidence interval [CI], 1.03-1.11; p = 0.001). Vitamin D status had a significant inverse association with body weight. The odds of vitamin D deficiency significantly increased by 4% with increasing one kg in weight (OR, 1.04; 95% CI, 1-1.08; p = 0.044). There were no significant association between serum vitamin D level and intra cellular adhesion molecule-1, interleukin-17, fasting blood glucose, and lipid profile (p > 0.05). Considering the inverse association observed between serum vitamin D with EF% and body weight, vitamin D may play a role in modulating of these indices.

Keywords

Acknowledgement

We thank all the patients at the Imam Ali Hospital in Kermanshah, Iran who participated in this study.

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