Fisheries and Aquatic Sciences

The Korean Society of Fisheries and Aquatic Science (한국수산과학회)
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Tyrosinase inhibition effects of Korean edible brown, green, and red seaweed extracts

  • Ju-Won Ryu (Department of Food Science and Technology, Dong-Eui University) ;
  • Mi-Jin Yim (National Marine Biodiversity Institute of Korea) ;
  • Ji-Yul Kim (National Marine Biodiversity Institute of Korea) ;
  • Jeong Min Lee (National Marine Biodiversity Institute of Korea) ;
  • Myeong Seok Lee (National Marine Biodiversity Institute of Korea) ;
  • Dae-Sung Lee (National Marine Biodiversity Institute of Korea) ;
  • Ji-Young Hwang (Department of Food Science and Technology, Dong-Eui University) ;
  • Kyung Tae Kim (Department of Food Science and Technology, Dong-Eui University) ;
  • Young-Mog Kim (Department of Food Science and Technology, Pukyoung National University) ;
  • Sung-Hwan Eom (Department of Food Science and Technology, Dong-Eui University)
  • Received : 2023.12.03
  • Accepted : 2024.03.08
  • Published : 2024.07.31
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Abstract

The tyrosinase inhibition effects of 23 marine-derived seaweeds harvested in Korea were screened to determine their potential as skin-whitening agents. Of the 23 species initially screened, the total phenolic (TP) content of brown, green, and red seaweeds were 7.62-280.11, 5.24-62.37, and 0.63-28.76 phloroglucinol equivalents (PGE) mg/g, respectively. Brown seaweed extracts exhibited much stronger inhibitory activities than green and red seaweed extracts. Among the brown seaweeds, Ecklonia cava had the highest TP content (280.11 PGE mg/g) and the strongest tyrosinase inhibitory effect with a half maximal inhibitory concentration (IC50) value of 4.38 ㎍/mL. The kinetics of tyrosinase inhibition, analyzed by Lineweaver-Burk plots, found E. cava extract to be a non-competitive inhibitor. This study's results indicated that E. cava's inhibition of tyrosinase may have potential applications in the cosmetic industry.

Keywords

Acknowledgement

This work was supported by National Marine Biodiversity Institute of Korea Research Program 2024M00500.

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