Journal of Animal Science and Technology

Korean Society of Animal Sciences and Technology (한국축산학회)
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Complete genome sequence of Latilactobacillus curvatus CACC879 and its functional probiotic properties

  • Soyeon Park (Department of Research and Development, Center for Industrialization of Agricultural and Livestock Microorganisms) ;
  • Seoyun Son (Department of Research and Development, Center for Industrialization of Agricultural and Livestock Microorganisms) ;
  • Mi Ae Park (Department of Research and Development, Center for Industrialization of Agricultural and Livestock Microorganisms) ;
  • Dae-Hyuk Kim (Department of Research and Development, Center for Industrialization of Agricultural and Livestock Microorganisms) ;
  • Yangseon Kim (Department of Research and Development, Center for Industrialization of Agricultural and Livestock Microorganisms)
  • Received : 2023.05.02
  • Accepted : 2023.05.23
  • Published : 2024.05.31
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Abstract

Latilactobacillus curvatus CACC879 originated from swine feces in Korea, and its probiotic properties have been analyzed. The complete genome of strain CACC879 contained one chromosome 1,398,247 bp in length and three circular plasmids, namely, pCACC879-1 (591,981 bp), pCACC879-2 (14,542 base pairs [bp]), and pCACC879-3 (45,393 bp). The complete genome encodes a total of 2,077 genes, including 25 rRNA genes and 90 tRNA genes. In addition, probiotic stability- genes acid/bile related to salts tolerance, the biosynthesis of cobalamin (vitamin B12), riboflavin (vitamin B2), and CRISPR/Cas9 were found in the whole genomes. Remarkably, L. curvatus CACC879 contained the antioxidant-related (peroxiredoxin) and bacteriocin-related genes (lysM and blpA). Overall, these results demonstrate that L. curvatus CACC879 is a functional probiotic candidate for animal industry applications.

Keywords

Acknowledgement

This research was supported by INNOPOLIS FOUNDATION through Science and Technology Project Opens the Future of the Region, which is funded by Ministry of Science and ICT (Project No. 171177233), Korea, and partially supported by 2022 Technology commercialization support project Ministry of Agriculture, Food and Rural Afairs, Korea (Project No. 122037-02).

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