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Blood Test for Allergies Related to Environmental Diseases in Households Vulnerable to Indoor Air Quality in Daejeon Metropolitan City

대전광역시 내 실내공기질 취약 가구의 환경성질환 연관 알레르기 혈액검사 시행 효과

  • Hee Won Seo (Department of Biomedical Laboratory Science, Daejeon University) ;
  • Ji Hae Oh (Department of Biomedical Laboratory Science, Daejeon University) ;
  • Seung Hwa Baek (Department of Biomedical Laboratory Science, Daejeon University) ;
  • Seock Yeon Hwang (Department of Biomedical Laboratory Science, Daejeon University)
  • 서희원 (대전대학교 임상병리학과) ;
  • 오지혜 (대전대학교 임상병리학과) ;
  • 백승화 (대전대학교 임상병리학과) ;
  • 황석연 (대전대학교 임상병리학과)
  • Received : 2024.07.01
  • Accepted : 2024.08.12
  • Published : 2024.08.31

Abstract

Background: Based on rapid industrial development, environmental pollution has emerged as a social problem and exposure to environmental diseases is increasing. The number of patients suffering environmental diseases in Daejeon Metropolitan City is also steadily increasing, and the prevalence of atopic dermatitis there is the highest in the country. Objectives: In order to minimize exposure to harmful factors for the prevention and management of environmental diseases, an environmental disease management system suitable for the environmental characteristics of each region is needed. Basic preliminary research should be conducted to identify environmental hazards in Daejeon Metropolitan City and establish a management system. Methods: Among the households (about 50 people) participating in the 2022 Indoor Environment Remote Measurement (IoT) program, households (children aged 5 or older and adults) with insufficient results for indoor air quality measurement and symptoms related to environmental diseases were selected. The subjects were tested for living conditions, blood tests, biomarker analysis (immunoglobulin E, Eosinophil count, histamine) and multiple allergy antigen tests (MAST, 93 types). Results: Participants were 53.7% female and 46.3% male, and the average age showed an even age distribution. IgE and eosinophil count were positively correlated, and significant results were found for atopic dermatitis and IgE (p<0.05). Typical risk factors observed in the survey was the amount of indoor ventilation, chemical exposure, heredity, house dust mites, fungi, and food. Conclusions: The purpose of this study was to help establish a regional management system for environmental diseases, research and diagnosis of environmental diseases. This study is meaningful in that it is a study with customized consulting suitable for the environment of Daejeon Metropolitan City. If the limitations are addressed and continuous research is conducted, it will be helpful for the management, diagnosis, and research of environmental diseases.

Keywords

Acknowledgement

본 연구는 환경부 지정 대전광역시 환경보건센터 연구비(2023년) 지원으로 이루어졌습니다.

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