Journal of Ginseng Research

The Korean Society of Ginseng (고려인삼학회)
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The synergistic effects of Korean Red Ginseng and Cervi Parvum Cornu ameliorating FeCl3-induced arterial thrombosis by downregulating ICAM-1 and VCAM-1

  • Yi-Seong Kwak (R&D Headquarters, Korea Ginseng Corporation) ;
  • Mohammad Amjad Hossain (College of Veterinary Medicine, Biosafety Research Institute, Jeonbuk National University) ;
  • Ajay Vijayakumar (College of Veterinary Medicine, Biosafety Research Institute, Jeonbuk National University) ;
  • Chang Won Kang (College of Veterinary Medicine, Biosafety Research Institute, Jeonbuk National University) ;
  • Chul Park (College of Veterinary Medicine, Biosafety Research Institute, Jeonbuk National University) ;
  • Sang-Youel Park (College of Veterinary Medicine, Biosafety Research Institute, Jeonbuk National University) ;
  • Jong-Hoon Kim (College of Veterinary Medicine, Biosafety Research Institute, Jeonbuk National University)
  • Received : 2024.02.19
  • Accepted : 2024.06.04
  • Published : 2024.09.01
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Abstract

In this study, we compared antithrombotic activities of Korean Red Ginseng (KRG) and Cervi Parvum Cornu (CPC) on rats with induced thrombosis. Results indicate that KRG and CPC suppressed the arterial occlusion and the combination of KRG and CPC (KRG + CPC) treatment exhibited a synergistic effect with maximum reduction in thrombosis.

Keywords

Acknowledgement

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education(2019R1A6A1A03033084). This work was supported by the 2019 grant from the Korean Society of Ginseng.

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