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Complete Genome Sequences of Two Quinolone-Resistant Methicillin-Resistant Staphylococcus aureus Strains Isolated from Broilers in Korea

  • Gi Yong Lee (Department of Veterinary Microbiology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) ;
  • Soo-Jin Yang (Department of Veterinary Microbiology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)
  • Received : 2024.01.16
  • Accepted : 2024.02.26
  • Published : 2024.03.28

Abstract

Fluoroquinolones have been extensively used in treatment or prevention of serious infections in humans and food-producing animals, especially in poultry, due to their broad-spectrum activity to both Gram-positive and -negative pathogens. However, the use of fluoroquinolones in poultry production selects for bacteria carrying genetic determinants for quinolone resistance. Here, we present the complete genome sequences of two methicillin-resistant Staphylococcus aureus (MRSA) strains displaying quinolone resistance, which were isolated from healthy broilers in Korea.

Keywords

Acknowledgement

This study was supported by funds from Research of Korea Centers for Disease Control and Prevention (Project No. 2017NER54060) and Ministry of Food and Drug Safety (2319MFDS012).

References

  1. World Health Organization (WHO). 2023. WHO Medically Important Antimicrobial List.
  2. World Organisation for Animal Health (OIE). 2021. OIE List of Antimicrobial Agents of Veterinary Importance.
  3. Lee GY, Lee SI, Kim SD, Park JH, Kim GB, Yang SJ. 2022. Clonal distribution and antimicrobial resistance of methicillin-susceptible and -resistant Staphylococcus aureus strains isolated from broiler farms, slaughterhouses, and retail chicken meat. Poult. Sci. 101: 102070.
  4. Kim YB, Seo KW, Jeon HY, Lim SK, Lee YJ. 2018. Characteristics of the antimicrobial resistance of Staphylococcus aureus isolated from chicken meat produced by different integrated broiler operations in Korea. Poult. Sci. 97: 962-969.
  5. Seemann T. 2014. Prokka: rapid prokaryotic genome annotation. Bioinformatics 30: 2068-2069.
  6. Overbeek R, Olson R, Pusch GD, Olsen GJ, Davis JJ, Disz T, et al. 2014. The seed and the rapid annotation of microbial genomes using Subsystems Technology (RAST). Nucleic Acids Res. 42: D206-214.
  7. Moon DC, Kim BY, Tamang MD, Nam HM, Jang GC, Jung SC, et al. 2016. Genome sequence of a unique t2247-ST692-III livestock-associated methicillin-resistant Staphylococcus aureus strain from chicken carcass. Genome Announc. 4: e00026-16.
  8. Ip M, Wang Z, Lam WY, Zhou H, Tsui S. 2014. Draft genome sequence of methicillin-resistant Staphylococcus aureus CUHK_188 (ST188), a health care-associated bacteremic isolate from Hong Kong. Genome Announc. 2: e00255-14.
  9. Yoon SH, Ha SM, Lim J, Kwon S, Chun J. 2017. A large-scale evaluation of algorithms to calculate average nucleotide identity. Antonie Van Leeuwenhoek 110: 1281-1286.