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High-Quality Whole Genome Sequence of a Linezolid-Resistant and Vancomycin-Susceptible Enterococcus faecalis Isolate ES-2-1 from a Pig Stool in South Korea

  • Jun Bong Lee (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Nguyen Thi Mai Tho (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Se Kye Kim (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Jang Won Yoon (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
  • Received : 2024.02.14
  • Accepted : 2024.03.18
  • Published : 2024.03.28

Abstract

We report the whole genome sequence of a linezolid-resistant and vancomycin-susceptible Enterococcus faecalis strain, ES-2-1, which was isolated from a pig stool in South Korea. The assembled genome of ES-2-1 consists of a 2,648,168-bp circular chromosome containing the optrA gene (encoding the ABC-F type ribosomal protection protein), an 84,891-bp plasmid containing numerous antimicrobial resistance genes, and an 82,106-bp cryptic plasmid. The ES-2-1 strain belongs to sequence type 1024 (ST1024) and carries multidrug resistant genes including the optrA (oxazolidinone phenicol transferable resistance A) gene, which confers linezolid resistance.

Keywords

Acknowledgement

This work was supported by a grant from Research of Korea Centers for Disease Control and Prevention (2021ER220100), Republic of Korea.

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