Korean Circulation Journal

  • 제54권8호
  • /
  • Pages.454-465
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  • 2024
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  • 1738-5520(pISSN)
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  • 1738-5555(eISSN)
대한심장학회 (The Korean Society of Cardiology)
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Clinical Outcomes After Drug-Coated Balloon Treatment in Popliteal Artery Disease: K-POP Registry 12-Month Results

  • Jong-Il Park (Division of Cardiology, Yeungnam University Medical Center, Yeungnam University College of Medicine) ;
  • Young-Guk Ko (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Seung-Jun Lee (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Chul-Min Ahn (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Seung-Woon Rha (Division of Cardiology, Korea University Guro Hospital) ;
  • Cheol-Woong Yu (Division of Cardiology, Korea University Anam Hospital) ;
  • Jong Kwan Park (Division of Cardiology, National Health Insurance Service Ilsan Hospital) ;
  • Sang-Ho Park (Division of Cardiology, Soonchunhyang University Cheonan Hospital) ;
  • Jae-Hwan Lee (Division of Cardiology, Chungnam National University Sejong Hospital) ;
  • Su-Hong Kim (Division of Cardiology, Busan Veterans Hospital) ;
  • Yong-Joon Lee (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Sung-Jin Hong (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Jung-Sun Kim (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Byeong-Keuk Kim (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Myeong-Ki Hong (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Donghoon Choi (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine)
  • 투고 : 2024.01.03
  • 심사 : 2024.04.04
  • 발행 : 2024.08.01
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초록

Background and Objectives: The popliteal artery is generally regarded as a "no-stent zone." Limited data are available on the outcomes of drug-coated balloons (DCBs) for popliteal artery disease. This study aimed to evaluate the 12-month clinical outcomes among patients who received DCB treatment for atherosclerotic popliteal artery disease. Methods: This prospective, multicenter registry study enrolled 100 patients from 7 Korean endovascular centers who underwent endovascular therapy using IN.PACT DCB (Medtronic) for symptomatic atherosclerotic popliteal artery disease. The primary endpoint was 12-month clinical primary patency and the secondary endpoint was clinically driven target lesion revascularization (TLR)-free rate. Results: The mean age of the study cohort was 65.7±10.8 years, and 77% of enrolled patients were men. The mean lesion length was 93.7±53.7 mm, and total occlusions were present in 45% of patients. Technical success was achieved in all patients. Combined atherectomy was performed in 17% and provisional stenting was required in 11%. Out of the enrolled patients, 91 patients completed the 12-month follow-up. Clinical primary patency and TLR-free survival rates at 12 months were 76.0% and 87.2%, respectively. A multivariate Cox regression analysis identified female and longer lesion length as the significant independent predictors of loss of patency. Conclusions: DCB treatment yielded favorable 12-month clinical primary patency and TLR-free survival outcomes in patients with popliteal artery disease.

키워드

과제정보

This study was supported by grants from Medtronic (Santa Rosa, CA, USA); the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) (No. HI20C1566) and the Bio & Medical Technology Development Program of the National Research Foundation & MSIT (No.2020M3A9I4038455); the PatientCentered Clinical Research Coordinating Center (PACEN), funded by the Ministry of Health & Welfare, Republic of Korea (HC20C0081); and the Korea Medical Device Development Fund, funded by the Korean government (202011B29-03, 202011D12-02) and the Cardiovascular Research Center (Seoul, Korea).

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