Korean Journal of Radiology

  • 제25권8호
  • /
  • Pages.706-714
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  • 2024
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  • 1229-6929(pISSN)
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  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
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Fluoroscopy-Guided Percutaneous Transthoracic Pleural Forceps Biopsy in Patients With Exudative Pleural Effusion

  • Doo Ri Kim (Department of Radiology, Jeju National University School of Medicine, Jeju National University Hospital) ;
  • In Chul Nam (Department of Radiology, Jeju National University School of Medicine, Jeju National University Hospital) ;
  • Hye Jin Baek (Department of Radiology, Gyeongsang National University School of Medicine, Gyeongsang National University Changwon Hospital) ;
  • Jeong Jae Kim (Department of Radiology, Jeju National University School of Medicine, Jeju National University Hospital) ;
  • Im Kyung Hwang (Department of Radiology, Jeju National University School of Medicine, Jeju National University Hospital) ;
  • Jeong Sub Lee (Department of Radiology, Jeju National University School of Medicine, Jeju National University Hospital) ;
  • Duk Ju Kim (Department of Radiology, Jeju National University School of Medicine, Jeju National University Hospital) ;
  • Chang Lim Hyun (Department of Pathology, Jeju National University School of Medicine, Jeju National University Hospital) ;
  • Sung Eun Park (Department of Radiology, Gyeongsang National University School of Medicine, Gyeongsang National University Changwon Hospital) ;
  • Sung Wook Song (Department of Emergency Medicine, Jeju National University School of Medicine, Jeju National University Hospital)
  • 투고 : 2023.09.30
  • 심사 : 2024.06.06
  • 발행 : 2024.08.01
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초록

Objective: This study aimed to evaluate the diagnostic performance and procedural characteristics of fluoroscopy-guided percutaneous transthoracic pleural forceps biopsy (PTPFB) in patients with exudative pleural effusion. Materials and Methods: Patients with exudative pleural effusion who underwent PTPFB between May 1, 2014, and February 28, 2023, were included in this retrospective study. The interval between percutaneous catheter drainage (PCD) and PTPFB, number of biopsies, procedural time, and procedure-related complications were evaluated. The sensitivity, specificity, and accuracy of diagnosing malignancy were computed for pleural cytology using PCD drainage, PTPFB, and combined PTPFB and pleural cytology. Results: Seventy-one patients, comprising 50 male and 21 female (mean age, 69.5 ± 15.3 years), were included in this study. The final diagnoses were benign lesions in 48 patients (67.6%) and malignant in 23 patients (32.4%). The overall interval between PCD and biopsy was 2.4 ± 3.7 days. The interval between PCD and biopsy in the group that underwent delayed PTPFB was 5.2 ± 3.9 days. The mean number of biopsies was 4.5 ± 1.3. The mean procedural time was 4.4 ± 2.1 minutes. Minor bleeding complications were reported in one patient (1.4%). The sensitivity, specificity, and accuracy for pleural cytology, PTPFB, and combined PTPFB and pleural cytology were 47.8% (11/23), 100% (48/48), and 83.1% (59/71), respectively; 65.2% (15/23), 100% (48/48), and 88.7% (63/71), respectively; and 78.3% (18/23), 100% (48/48), and 93.0% (66/71), respectively. The sensitivity and accuracy of cytology combined with PTPFB were significantly higher than those of cytological testing alone (P = 0.008 and 0.001, respectively). Conclusion: Fluoroscopy-guided PTPFB is an accurate and safe diagnostic technique for patients with exudative pleural effusion, with acceptable diagnostic performance, low complication rates, and reasonable procedural times.

키워드

과제정보

This work was supported by a research grant from Jeju National University Hospital in 2023 (2023-20).

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