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Economic Burden of Chronic Obstructive Pulmonary Disease: A Systematic Review

  • Hai Quang Pham (Department of Health Economics, School of Preventive Medicine and Public Health, Hanoi Medical University) ;
  • Kiet Huy Tuan Pham (Department of Health Economics, School of Preventive Medicine and Public Health, Hanoi Medical University) ;
  • Giang Hai Ha (Institute of Theoretical and Applied Research, Duy Tan University) ;
  • Tin Trung Pham (Can Tho University of Medicine and Pharmacy, Faculty of Public Health) ;
  • Hien Thi Nguyen (Can Tho University of Medicine and Pharmacy, Faculty of Public Health) ;
  • Trang Huyen Thi Nguyen (Department of Cancer Control and Population Health, Graduate School of Cancer Science and Policy, National Cancer Center) ;
  • Jin-Kyoung Oh (Department of Cancer Control and Population Health, Graduate School of Cancer Science and Policy, National Cancer Center)
  • Received : 2023.07.17
  • Accepted : 2024.02.05
  • Published : 2024.07.31

Abstract

Globally, providing evidence on the economic burden of chronic obstructive pulmonary disease (COPD) is becoming essential as it assists the health authorities to efficiently allocate resources. This study aimed to summarize the literature on economic burden evidence for COPD from 1990 to 2019. This study examined the economic burden of COPD through a systematic review of studies from 1990 to 2019. A search was done in online databases, including Web of Science, PubMed/Medline, Scopus, and the Cochrane Library. After screening 12,734 studies, 43 articles that met the inclusion criteria were identified. General study information and data on direct, indirect, and intangible costs were extracted and converted to 2018 international dollars (Int$). Findings revealed that the total direct costs ranged from Int$ 52.08 (India) to Int$ 13,776.33 (Canada) across 16 studies, with drug costs rannging from Int$ 70.07 (Vietnam) to Int$ 8,706.9 (China) in 11 studies. Eight studies explored indirect costs, while one highlighted caregivers' direct costs at approximately Int$ 1,207.8 (Greece). This study underscores the limited research on COPD caregivers' economic burdens, particularly in developing countries, emphasizing the importance of increased research support, particularly in high-resource settings. This study provides information about the demographics and economic burden of COPD from 1990 to 2019. More strategies to reduce the frequency of hospital admissions and acute care services should be implemented to improve the quality of COPD patients' lives and reduce the disease's rising economic burden.

Keywords

Acknowledgement

This work was supported by the Domestic Master/PhD Scholarship Program of Vingroup Innovation Foundation. One of the authors, Trang Huyen Thi Nguyen, received funding from the International Cooperation and Education Program (NCCRI·NCCI 52210-52211, 2023) of the National Cancer Center, Korea.

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