International Journal of Stem Cells

  • 제17권2호
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  • Pages.147-157
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  • 2024
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  • 2005-3606(pISSN)
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  • 2005-5447(eISSN)
한국줄기세포학회 (Korean Society for Stem Cell Research)
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Guidelines for Manufacturing and Application of Organoids: Lung

  • 투고 : 2024.04.08
  • 심사 : 2024.05.07
  • 발행 : 2024.05.30
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초록

The objective of standard guideline for utilization of human lung organoids is to provide the basic guidelines required for the manufacture, culture, and quality control of the lung organoids for use in non-clinical efficacy and inhalation toxicity assessments of the respiratory system. As a first step towards the utilization of human lung organoids, the current guideline provides basic, minimal standards that can promote development of alternative testing methods, and can be referenced not only for research, clinical, or commercial uses, but also by experts and researchers at regulatory institutions when assessing safety and efficacy.

키워드

과제정보

This research was supported by Ministry of Food and Drug Safety in 2023 (grant number: 23212MFDS265) and Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education (grant number: 2021K1A4A7A0209775712).

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