International Journal of Stem Cells

Korean Society for Stem Cell Research (한국줄기세포학회)
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Guidelines for Manufacturing and Application of Organoids: Kidney

  • Hyun Mi Kang (Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ;
  • Dong Sung Kim (Organoid Standards Initiative) ;
  • Yong Kyun Kim (Organoid Standards Initiative) ;
  • Kunyoo Shin (Organoid Standards Initiative) ;
  • Sun-Ju Ahn (Organoid Standards Initiative) ;
  • Cho-Rok Jung (Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB))
  • Received : 2024.04.08
  • Accepted : 2024.05.02
  • Published : 2024.05.30
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Abstract

Recent advancements in organoid technology have led to a vigorous movement towards utilizing it as a substitute for animal experiments. Organoid technology offers versatile applications, particularly in toxicity testing of pharmaceuticals or chemical substances. However, for the practical use in toxicity testing, minimal guidance is required to ensure reliability and relevance. This paper aims to provide minimal guidelines for practical uses of kidney organoids derived from human pluripotent stem cells as a toxicity evaluation model in vitro.

Keywords

Acknowledgement

Authors appreciated Organoid Standards Initiative committee members, raised considerable recommends to improve this guideline.

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