Clinical Endoscopy

  • 제57권3호
  • /
  • Pages.342-349
  • /
  • 2024
  • /
  • 2234-2400(pISSN)
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  • 2234-2443(eISSN)
대한소화기내시경학회 (The Korean Society of Gastrointestinal Endoscopy)
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Clinical outcomes of nonvariceal upper gastrointestinal bleeding in nonagenarians and octogenarians: a comparative nationwide analysis

  • Khaled Elfert (Department of Internal Medicine, SBH Health System) ;
  • James Love (Department of Medicine, University of Illinois at Chicago) ;
  • Esraa Elromisy (Tanta University Faculty of Medicine) ;
  • Fouad Jaber (Department of Internal Medicine, University of Missouri-Kansas City School of Medicine) ;
  • Suresh Nayudu (Division of Gastroenterology, SBH Health System) ;
  • Sammy Ho (Division of Gastroenterology, Montefiore Medical Center, Albert Einstein College of Medicine) ;
  • Michel Kahaleh (Division of Gastroenterology, Department of Medicine, Robert Wood Johnson University Hospital)
  • 투고 : 2023.05.11
  • 심사 : 2023.07.13
  • 발행 : 2024.05.30
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초록

Background/Aims: Nonagenarians will purportedly account for 10% of the United States population by 2050. However, no studies have assessed the outcomes of nonvariceal upper gastrointestinal bleeding (NVUGIB) in this age group. Methods: The National Inpatient Sample database between 2016 and 2020 was used to compare the clinical outcomes of NVUGIB in nonagenarians and octogenarians and evaluate predictors of mortality and the use of esophagogastroduodenoscopy (EGD). Results: Nonagenarians had higher in-hospital mortality than that of octogenarians (4% vs. 3%, p<0.001). EGD utilization (30% vs. 48%, p<0.001) and blood transfusion (27% vs. 40%, p<0.001) was significantly lower in nonagenarians. Multivariate logistic regression analysis revealed that nonagenarians with NVUGIB had higher odds of mortality (odds ratio [OR], 1.5; 95% confidence interval [CI], 1.3-1.7) and lower odds of EGD utilization (OR, 0.86; 95% CI, 0.83-0.89) than those of octogenarians. Conclusions: Nonagenarians admitted with NVUGIB have a higher mortality risk than that of octogenarians. EGD is used significantly in managing NVUGIB among nonagenarians; however, its utilization is comparatively lower than in octogenarians. More studies are needed to assess predictors of poor outcomes and the indications of EGD in this growing population.

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참고문헌

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