The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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A Case Report of Complex Korean Medicine Treatment Including Modified Gamiguibi-tang in a Paraneoplastic Cerebellar Degeneration Patient with Dysarthria and Weakness of Distal Extremity

구음장애와 사지원위부 무력감을 호소하는 신생물딸림소뇌변성 환자에 대한 가미귀비탕가감방을 포함한 한의복합치료 1례

  • Ji-hyeon Kang (Dept. of Cardiovascular and Neurologic Diseases of Korean Internal Medicine, Daegu Haany University Korean Medicine Hospital) ;
  • Seo-hyun Kim (Dept. of Cardiovascular and Neurologic Diseases of Korean Internal Medicine, Daegu Haany University Korean Medicine Hospital) ;
  • Chae-eun Kim (Dept. of Cardiovascular and Neurologic Diseases of Korean Internal Medicine, Daegu Haany University Korean Medicine Hospital) ;
  • Hee-ju Won (Dept. of Cardiovascular and Neurologic Diseases of Korean Internal Medicine, Daegu Haany University Korean Medicine Hospital) ;
  • Kyungmin Baek (Dept. of Cardiovascular and Neurologic Diseases of Korean Internal Medicine, Daegu Haany University Korean Medicine Hospital)
  • 강지현 (대구한의대한방병원 심계내과학교실) ;
  • 김서현 (대구한의대한방병원 심계내과학교실) ;
  • 김채은 (대구한의대한방병원 심계내과학교실) ;
  • 원희주 (대구한의대한방병원 심계내과학교실) ;
  • 백경민 (대구한의대한방병원 심계내과학교실)
  • Received : 2024.05.25
  • Accepted : 2024.07.02
  • Published : 2024.06.30
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Abstract

Objectives: This study investigated the treatment response to Korean medicine of a paraneoplastic cerebellar degeneration (PCD) patient with dysarthria and weakness of distal extremity. Case presentation: A 53-year-old female diagnosed with PCD complained of dysarthria and weakness of distal extremity. During 32-day hospitalization, she was treated with Korean medicine, namely, herbal medicine (modified Gamiguibi-tang), acupuncture (15 minutes twice a day at CV23, HT7, LI4, LR3, ST36, SP6, GB20, TE17, PC6, GV20, Ex-HN1, GV24 etc.), moxibustion, and cupping, combined with Western medicine (prednisolone, azathioprine) and physical therapy. Post-treatment, the patient global assessment (PGA) score of dysarthria fell from 100 to 60; grasp power rose from 15 kg to 19 kg and 13 kg to 17 kg in the right and left hands, respectively; and the 5-level EQ-5D version (EQ-5D-5L), EQ visual analogue scale (EQ-VAS), and Beck depression inventory (BDI-II) scores changed from 10 to 8, 0 to 80, and 34 to 7 respectively. Follow-up visits continued for about a month after discharge, improvement in symptoms maintained, and there were no significant side effects. Conclusions: Given the lack of standard treatment for PCD, Korean medicine can be tried clinically for the treatment of PCD patients with dysarthria and weakness of distal extremity. However, further studies with control groups are needed.

Keywords

References

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