과제정보
This work was supported by the National Research Foundation of Korea (NRF) funded by the Korean Government (MSIT) (NRF-2021R1F1A1055482).
참고문헌
- Liu X, Xia S, Zhang Z, Wu H, Lieberman J. 2021. Channelling inflammation: gasdermins in physiology and disease. Nat. Rev. Drug Discov. 20: 384-405.
- Ross EA, Devitt A, Johnson JR. 2021. Macrophages: the good, the bad, and the gluttony. Front. Immunol. 12: 708186.
- Palsson-McDermott EM, O'Neill LA. 2020. Targeting immunometabolism as an anti-inflammatory strategy. Cell Res. 30: 300-314.
- Sharma P, Shri R, Ntie-Kang F, Kumar S. 2021. Phytochemical and ethnopharmacological perspectives of Ehretia laevis. Molecules 26: 3489.
- Shukla A, Kaur A. 2018. A systematic review of traditional uses bioactive phytoconstituents of genus Ehretia. Asian J. Pharm. Clin. Res. 11: 88-100.
- Zhang WN, Tong WY. 2016. Chemical constituents and biological activities of plants from the genus Physalis.Chem. Biodiver. 13: 48-65.
- Ashagrie G, Abebe A, Umer S. 2023. Analgesic and anti-inflammatory activities of 80% methanol extract and solvent fractions of Ehretia cymosa Thonn (Boraginaceae) leaves in rodents. J. Exper. Pharmacol. 15: 63-79.
- Dong M, Oda Y, Hirota M. 2000. (10E, 12Z, 15Z)-9-hydroxy-10, 12, 15-octadecatrienoic acid methyl ester as an anti-inflammatory compound from Ehretia dicksonii. Biosci. Biotechnol. Biochem. 64: 882-886.
- Kaur A, Shukla A, Shukla RK. 2022. In vitro antidiabetic and anti-inflammatory activities of the bark of Ehretia acuminata R. Br. Indian J. Nat. Products Resour (IJNPR)[Formerly Natural Product Radiance (NPR)] 12: 538-543.
- Repetto G, Del Peso A, Zurita JL. 2008. Neutral red uptake assay for the estimation of cell viability/cytotoxicity. Nat. Protocols 3: 1125-1131.
- Sun J, Zhang X, Broderick M, Fein H. 2003. Measurement of nitric oxide production in biological systems by using griess reaction assay. Sensors 3: 276-284.
- Schmittgen TD, Livak KJ. 2008. Analyzing real-time PCR data by the comparative CT method. Nat. Protocols 3: 1101-1108.
- Fujiwara N, Kobayashi K. 2005. Macrophages in inflammation. Curr. Drug Targets-Inflamm. Allergy 4: 281-286.
- Rathee P, Chaudhary H, Rathee S, Rathee D, Kumar V, Kohli K. 2009. Mechanism of action of flavonoids as anti-inflammatory agents: a review. Inflamm. Allergy Drug Targets 8: 229-235.
- Viet TD, Xuan TD, Van TM, Andriana Y, Rayee R, Tran H-D. 2019. Comprehensive fractionation of antioxidants and GC-MS and ESI-MS fingerprints of Celastrus hindsii leaves. Medicines 6: 64.
- Nanjundaiah SM, Venkatesha SH, Yu H, Tong L, Stains JP, Moudgil KD. 2012. Celastrus and its bioactive celastrol protect against bone damage in autoimmune arthritis by modulating osteoimmune cross-talk. J. Biol. Chem. 287: 22216-22226.
- Li G, Liu D, Guo S, Sunagawa M, Hisamitsu T, Liu Y. 2014. Anti-invasive effects of Celastrus Orbiculatus extract on interleukin-1 beta and tumour necrosis factor-alpha combination-stimulated fibroblast-like synoviocytes. BMC Complement. Altern. Med. 14: 62.
- Wang H, Tao L, Ni T, Gu H, Jin F, Dai X, et al. 2017. Anticancer efficacy of the ethyl acetate extract from the traditional Chinese medicine herb Celastrus orbiculatus against human gastric cancer. J. Ethnopharmacol. 205: 147-157.
- Simmons DL, Botting RM, Hla T. 2004. Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition. Pharmacol. Rev. 56: 387-437.
- Grosch S, Maier TJ, Schiffmann S, Geisslinger G. 2006. Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. J. Natl. Cancer Inst. 98: 736-747.
- Zhang S, Qi Y, Xu Y, Han X, Peng J, Liu K, et al. 2013. Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation. Neurochem. Int. 63: 522-532.
- Desai SJ, Prickril B, Rasooly A. 2018. Mechanisms of phytonutrient modulation of cyclooxygenase-2 (COX-2) and inflammation related to cancer. Nutr. Cancer 70: 350-375.
- Samani P, Costa S, Cai S. 2023. Neuroprotective effects of blueberries through inhibition on cholinesterase, tyrosinase, cyclooxygenase-2, and amyloidogenesis. Nutraceuticals 3: 39-57.
- Tian C, Chang Y, Zhang Z, Wang H, Xiao S, Cui C, et al. 2019. Extraction technology, component analysis, antioxidant, antibacterial, analgesic and anti-inflammatory activities of flavonoids fraction from Tribulus terrestris L. leaves. Heliyon 5: e02234.
- Jin Z, Zhou A, Wang S, Zhao Y, Shu J, Song Y, et al. 2023. Study on the extraction process, chemical compositions, and anti-inflammatory activity of total saponins extract from Anemone raddeana Regel. Pharmacol. Res. Modern Chinese Med. 9: 100332.
- Thathsarani N, Jayasinghe CD, Jayawardena U, Nilakarawasam N. 2021. Effect of oral administration of the fresh juice of Bamboo (Bambusa vulgaris) young shoots on enumeration of bone marrow cells, platelets, splenocyte and phagocytic activity of peritoneal macrophages of rats. Phytomedicine Plus 1: 100059.
- Xin C, Kim J, Quan H, Yin M, Jeong S, Choi J-I, et al. 2019. Ginsenoside Rg3 promotes Fc gamma receptor-mediated phagocytosis of bacteria by macrophages via an extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent mechanism. Int. Immunopharmacol. 77: 105945.
- Guzik T, Korbut R, Adamek-Guzik T. 2003. Nitric oxide and superoxide in inflammation. J. physiol. pharmacol. 54: 469-487.
- Arango Duque G, Descoteaux A. 2014. Macrophage cytokines: involvement in immunity and infectious diseases. Front. Immunol. 5: 491.
- Yousaf H, Khan MIU, Ali I, Munir MU, Lee KY. 2023. Emerging role of macrophages in non-infectious diseases: An update. Biomed. Pharmacother. 161: 114426.
- Li W, Liu Q, Shi J, Xu X, Xu J. 2023. The role of TNF-α in the fate regulation and functional reprogramming of mesenchymal stem cells in an inflammatory microenvironment. Front. Immunol. 14: 1074863.
- Yaseen MM, Abuharfeil NM, Darmani H. 2023. The role of IL-1β during human immunodeficiency virus type 1 infection. Rev. Med. Virol. 33: e2400.
- den Haan JM, Arens R, van Zelm MC. 2014. The activation of the adaptive immune system: cross-talk between antigen-presenting cells, T cells and B cells. Immunol. Lett. 162: 103-112.
- Ryu JH, Ahn H, Kim JY, Kim YK. 2003. Inhibitory activity of plant extracts on nitric oxide synthesis in LPS-activated macrophages. Phytother. Res. 17: 485-489.
- Choi E-M, Hwang J-K. 2005. Screening of Indonesian medicinal plants for inhibitor activity on nitric oxide production of RAW264. 7 cells and antioxidant activity. Fitoterapia 76: 194-203.
- Nakamura T, Kodama N, Arai Y, Kumamoto T, Higuchi Y, Chaichantipyuth C, et al. 2009. Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-α, and COX-2 expression in mouse macrophage RAW 264.7. J. Nat. Med. 63: 21-27.
- Park JY, Pillinger MH, Abramson SB. 2006. Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases. Clin. Immunol. 119: 229-240.
- Lim JS, Lee SH, Yun H, Lee DY, Cho N, Yoo G, et al. 2023. Inhibitory effects of Ehretia tinifolia extract on the excessive oxidative and inflammatory responses in lipopolysaccharide-stimulated mouse kupffer cells. Antioxidants 12: 1792.