DOI QR코드

DOI QR Code

Orofacial Manifestations of Hyperparathyroidism: A Dental Perspective

  • Jo-Eun Park (Department of Orofacial Pain and Oral Medicine, Dankook University Dental Hospital)
  • Received : 2024.03.27
  • Accepted : 2024.05.24
  • Published : 2024.06.30

Abstract

Hyperparathyroidism (HPT) is a significant condition marked by the overproduction of parathyroid hormones, affecting both systemic health and orofacial regions. Predominantly, secondary HPT associated with chronic kidney disease (CKD) is critical because of its link to widespread conditions such as diabetes and hypertension. This short article highlights the vital role of dental professionals in identifying HPT through panoramic radiography, which can reveal critical orofacial signs such as brown tumors, altered dental development, and specific bone changes. With the CKD prevalence expected to increase alongside an aging population, the importance of early detection of HPT and its manifestations in dental settings cannot be overstated. Dental practitioners play a crucial role in the early detection of HPT, emphasizing the importance of being knowledgeable about its orofacial manifestations.

Keywords

References

  1. Antonelli JR, Hottel TL. Oral manifestations of renal osteodystrophy: case report and review of the literature. Spec Care Dentist 2003;23:28-34. 
  2. Palla B, Burian E, Fliefel R, Otto S. Systematic review of oral manifestations related to hyperparathyroidism. Clin Oral Investig 2018;22:1-27. 
  3. Ahmad R, Hammond JM. Primary, secondary, and tertiary hyperparathyroidism. Otolaryngol Clin North Am 2004;37:701-713, viiviii. 
  4. Das S, Majumder M, Das D, et al. Prevalence and risk factors of secondary hyperparathyroidism among CKD patients and correlation with different laboratory parameters. Mymensingh Med J 2022;31:1084-1092. 
  5. Aguilar A, Gifre L, Urena-Torres P, et al. Pathophysiology of bone disease in chronic kidney disease: from basics to renal osteodystrophy and osteoporosis. Front Physiol 2023;14:1177829. 
  6. Solt DB. The pathogenesis, oral manifestations, and implications for dentistry of metabolic bone disease. Curr Opin Dent 1991;1:783-791. 
  7. Silva MT, Cedraz JS, Pontes CG, et al. Brown tumor: clinical findings of secondary hyperparathyroidism in patients with renal osteodystrophy. Gen Dent 2017;65:70-74. 
  8. Roberts WE, Simmons KE, Garetto LP, DeCastro RA. Bone physiology and metabolism in dental implantology: risk factors for osteoporosis and other metabolic bone diseases. Implant Dent 1992;1:11-21.