Animal Bioscience

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
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Administration of chromium picolinate and meloxicam alleviates regrouping stress in dairy heifers

  • Da Jin Sol Jung (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Jaesung Lee (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Do Hyun Kim (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Seok-Hyeon Beak (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Soo Jong Hong (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • In Hyuk Jeong (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Seon Pil Yoo (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Jin Oh Lee (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • In Gu Cho (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Dilla Mareistia Fassah (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Hyun Jin Kim (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Mohammad Malekkhahi (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University) ;
  • Myunggi Baik (Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, College of Agriculture and Life Sciences, Seoul National University)
  • Received : 2024.02.22
  • Accepted : 2024.03.28
  • Published : 2024.08.01
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Abstract

Objective: This research investigated the effect of administering chromium (Cr) and meloxicam (MEL) on growth performance, cortisol and blood metabolite, and behaviors in young, regrouped heifers. Methods: Fifty Holstein dairy heifers (body weight [BW] 198±32.7 kg and 6.5±0.82 months of age) were randomly assigned to non-regrouped group or four regrouped groups. Non-regrouped animals were held in the same pen throughout the entire experimental period (NL: non-regrouping and administration of lactose monohydrate [LM; placebo]). For regrouping groups, two or three heifers maintained in four different pens for 2 weeks were regrouped into a new pen and assigned to one of four groups: regrouping and LM administration (RL); regrouping and Cr administration (RC); regrouping and MEL administration (RM), and regrouping and Cr and MEL administration (RCM). LM (1 mg/kg BW), Cr (0.5 mg Cr picolinate/kg dry matter intake), and MEL (1 mg/kg BW) were orally administered immediately before regrouping. Blood was collected before regrouping (0 h) and at 3, 9, and 24 h and 7 and 14 d thereafter. Behaviors were recorded for 7 consecutive days after regrouping. Results: Average daily gain was lower (p<0.05) in RL than NL heifers, but was higher (p<0.05) in RM, RC, and RCM than RL heifers. RL heifers had higher (p<0.05) cortisol than NL heifers on d 1 after regrouping. The cortisol concentrations in RC, RM, and RCM groups were lower (p<0.05) than in RL treatment 1 d after regrouping. Displacement behavior was greater (p<0.05) in RL group than all other groups at 2, 3, and 6 d after regrouping. Conclusion: Regrouping caused temporal stress, reduced growth performance, and increased displacement behavior in heifers. Administering Cr and MEL recovered the retarded growth rate and reduced displacement behavior, thereby alleviating regrouping stress.

Keywords

Acknowledgement

This work was supported by the Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (IPET) through the Advanced Production Technology Development Program, funded by the Ministry of Agriculture, Food and Rural Affairs (MAFRA) (118016-03).

References

  1. Veissier I, Boissy A, dePassille AM, et al. Calves' responses to repeated social regrouping and relocation. J Anim Sci 2001;79:2580-93. https://doi.org/10.2527/2001.79102580x
  2. Boe KE, Faerevik G. Grouping and social preferences in calves, heifers and cows. Appl Anim Behav Sci 2003;80:175-90. https://doi.org/10.1016/S0168-1591(02)00217-4
  3. Garnsworthy PC. Calf and heifer rearing. 1st ed. Nottingham, UK: Nottingham University Press; 2005.
  4. Raussi S, Boissy A, Delval E, Pradel P, Kaihilahti J, Veissier I. Does repeated regrouping alter the social behaviour of heifers? Appl Anim Behav Sci 2005;93:1-12. https://doi.org/10.1016/j.applanim.2004.12.001
  5. Cabrera VE, Kalantari AS. Economics of production efficiency: nutritional grouping of the lactating cow. J Dairy Sci 2016;99:825-41. https://doi.org/10.3168/jds.2015-9846
  6. Zelena D, Haller J, Halasz J, Makara GB. Social stress of variable intensity: physiological and behavioral consequences. Brain Res Bull 1999;48:297-302. https://doi.org/10.1016/s0361-9230(98)00176-2
  7. von Keyserlingk MAG, Olenick D, Weary DM. Acute behavioral effects of regrouping dairy cows. J Dairy Sci 2008;91:1011-6. https://doi.org/10.3168/jds.2007-0532
  8. Gonzalez M, Yabuta AK, Galindo F. Behaviour and adrenal activity of first parturition and multiparous cows under a competitive situation. Appl Anim Behav Sci 2003;83:259-66. https://doi.org/10.1016/S0168-1591(03)00037-6
  9. Colditz IG, Ferguson DM, Greenwood PL, Doogan VJ, Petherick JC, Kilgour RJ. Regrouping unfamiliar animals in the weeks prior to slaughter has few effects on physiology and meat quality in 'Bos taurus' feedlot steers. Aust J Exp Agric 2007;47:763-9. https://doi.org/10.1071/EA05114
  10. Silva PRB, Moraes JGN, Mendonca LGD, et al. Effects of weekly regrouping of prepartum dairy cows on metabolic, health, reproductive, and productive parameters. J Dairy Sci 2013;96:4436-46. https://doi.org/10.3168/jds.2012-6464
  11. Grant RJ, Albright JL. Effect of animal grouping on feeding behavior and intake of dairy cattle. J Dairy Sci 2001;84:E156-63. https://doi.org/10.3168/jds.S0022-0302(01)70210-X
  12. Heinrich A, Duffield TF, Lissemore KD, Millman ST. The effect of meloxicam on behavior and pain sensitivity of dairy calves following cautery dehorning with a local anesthetic. J Dairy Sci 2010;93:2450-7. https://doi.org/10.3168/jds.2009-2813
  13. Olson ME, Ralston B, Burwash L, Matheson-Bird H, Allan ND. Efficacy of oral meloxicam suspension for prevention of pain and inflammation following band and surgical castration in calves. BMC Vet Res 2016;12:102. https://doi.org/10.1186/s12917-016-0735-3
  14. Moonsie-Shageer S, Mowat DN. Effect of level of supplemental chromium on performance, serum constituents, and immune status of stressed feeder calves. J Anim Sci 1993;71:232-8. https://doi.org/10.2527/1993.711232x
  15. Soltan MA. Effect of dietary chromium supplementation on productive and reproductive performance of early lactating dairy cows under heat stress. J Anim Physiol Anim Nutr (Berl) 2010;94:264-72. https://doi.org/10.1111/j.1439-0396.2008.00913.x
  16. NRC. Nutrient requirements of dairy cattle. 7th Rev ed. Washington, DC, USA: The National Academies Press; 2001. https://doi.org/10.17226/9825
  17. Association of Official Analytical Chemists (AOAC). Official methods of analysis of AOAC international. 17th Ed. Gaithersburg, MD, USA: AOAC International; 2000.
  18. Van Soest PJ, Robertson JB, Lewis BA. Methods for dietary fiber, neutral detergent fiber and nonstarch polysaccharides in relation to animal nutrition. J Dairy Sci 1991;74:3583-97. https://doi.org/10.3168/jds.S0022-0302(91)78551-2
  19. Yoo S, Beak SH, Kang HJ, et al. Effect of knife castration on leukocyte cytokine expression and indicators of stress, pain, and inflammation in Korean cattle bull calves. Anim Biosci 2023;36:521-8. https://doi.org/10.5713/ab.22.0368
  20. Jung DJS, Kim DH, Beak SH, et al. Effects of vitamin E and selenium administration on transportation stress in pregnant dairy heifers. J Dairy Sci 2023;106:9576-86. https://doi.org/10.3168/jds.2023-23463
  21. Chibisa GE, Vinyard JR, Laarman AH. Short communication: effects of meloxicam administration on protein metabolism and growth performance in transported Jersey calves. J Dairy Sci 2018;101:11435-40. https://doi.org/10.3168/jds.2018-14493
  22. Soltan MA, Almujalli AM, Mandour MA, El-Shinway Abeer M. Effect of dietary chromium supplementation on growth performance, rumen fermentation characteristics and some blood serum units of fattening dairy calves under heat stress. Pak J Nutr 2012;11:849-54. https://doi.org/10.3923/pjn.2012.849.854
  23. McCarty MF. The therapeutic potential of glucose tolerance factor. Med Hypotheses 1980;6:1177-89. https://doi.org/10.1016/0306-9877(80)90140-1
  24. Filho TAG, Cooke RF, Cappellozza BI, Reis MM, Marques RS, Bohnert DW. Effects of meloxicam administration on physiological and performance responses of transported feeder cattle. J Anim Sci 2014;92:4137-44. https://doi.org/10.2527/jas.2014-7783
  25. Wilcox CS, Schutz MM, Rostagno MR, Lay DC, Eicher SD. Repeated mixing and isolation: measuring chronic, intermittent stress in Holstein calves. J Dairy Sci 2013;96:7223-33. https://doi.org/10.3168/jds.2013-6944
  26. Van Engen NK, Stock ML, Engelken T, et al. Impact of oral meloxicam on circulating physiological biomarkers of stress and inflammation in beef steers after long-distance transportation. J Anim Sci 2014;92:498-510. https://doi.org/10.2527/jas.2013-6857
  27. Heinrich A, Duffield TF, Lissemore KD, Squires EJ, Millman ST. The impact of meloxicam on postsurgical stress associated with cautery dehorning. J Dairy Sci 2009;92:540-7. https://doi.org/10.3168/jds.2008-1424
  28. Parker K, Rainey W, Griffin JE, Ojeda SR. Textbook of endocrine physiology. 5th ed. Oxford, England: Oxford University Press; 2004.
  29. Zentella de Pina M, Vazquez-Meza H, Pina-Zentella G, Pimentel L, Pina E. Non-steroidal anti-inflammatory drugs inhibit epinephrine- and cAMP-mediated lipolysis in isolated rat adipocytes. J Pharm Pharmacol 2002;54:577-82. https://doi.org/10.1211/0022357021778709
  30. McNamara JP, Valdez F. Adipose tissue metabolism and production responses to calcium propionate and chromium propionate. J Dairy Sci 2005;88:2498-507. https://doi.org/10.3168/jds.S0022-0302(05)72927-1
  31. Schirmann K, Chapinal N, Weary DM, Heuwieser W, von Keyserlingk MAG. Short-term effects of regrouping on behavior of prepartum dairy cows. J Dairy Sci 2011;94:2312-9. https://doi.org/10.3168/jds.2010-3639