Animal Bioscience

  • 제37권8호
  • /
  • Pages.1428-1439
  • /
  • 2024
  • /
  • 2765-0189(pISSN)
  • /
  • 2765-0235(eISSN)
아세아태평양축산학회 (Asian Australasian Association of Animal Production Societies)
권호 표지
DOI QR코드

DOI QR Code

Gut microbiota derived from fecal microbiota transplantation enhances body weight of Mimas squabs

  • Jing Ren (College of Animal Science, Jilin University) ;
  • Yumei Li (College of Animal Science, Jilin University) ;
  • Hongyu Ni (College of Animal Science, Jilin University) ;
  • Yan Zhang (College of Animal Science and Technology, Jilin Agricultural Science and Technology University) ;
  • Puze Zhao (College of Animal Science, Jilin University) ;
  • Qingxing Xiao (College of Animal Science, Jilin University) ;
  • Xiaoqing Hong (College of Animal Science, Jilin University) ;
  • Ziyi Zhang (College of Animal Science, Jilin University) ;
  • Yijing Yin (College of Animal Science, Jilin University) ;
  • Xiaohui Li (Center of Animal Experiment, College of Basic Medical Sciences, Jilin University) ;
  • Yonghong Zhang (College of Animal Science, Jilin University) ;
  • Yuwei Yang (College of Animal Science, Jilin University)
  • 투고 : 2023.11.09
  • 심사 : 2024.02.08
  • 발행 : 2024.08.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objective: Compared to Mimas pigeons, Shiqi pigeons exhibit greater tolerance to coarse feeding because of their abundant gut microbiota. Here, to investigate the potential of utilizing intestinal flora derived from Shiqi pigeons, the intestinal flora and body indices of Mimas squabs were evaluated after fecal microbiota transplantation (FMT) from donors. Methods: A total of 90 one-day-old squabs were randomly divided into the control group (CON), the low-concentration group (LC) and the high-concentration group (HC): gavaged with 200 μL of bacterial solution at concentrations of 0, 0.1, and 0.2 g/15 mL, respectively. Results: The results suggested that FMT improved the body weight of Mimas squabs in the HC and LC groups (p<0.01), and 0.1 g/15 mL was the optimal dose during FMT. After 16S rRNA sequencing was performed, compared to those in the CON group, the abundance levels of microflora, especially Lactobacillus, Muribaculaceae, and Megasphaera (p<0.05), in the FMT-treated groups were markedly greater. Random forest analysis indicated that the main functions of key microbes involve pathways associated with metabolism, further illustrating their important role in the host body. Conclusion: FMT has been determined to be a viable method for augmenting the weight and intestinal microbiota of squabs, representing a unique avenue for enhancing the economic feasibility of squab breeding.

키워드

과제정보

The authors thank Yumei Li, Yonghong Zhang, and Yuwei Yang for critical reading of the manuscript.

참고문헌

  1. El-Salhy M, Patcharatrakul T, Gonlachanvit S. Fecal microbiota transplantation for irritable bowel syndrome: an intervention for the 21(st) century. World J Gastroenterol 2021;27:2921-43. https://doi.org/10.3748/wjg.v27.i22.2921 
  2. Wang X, Wu X, Cong X, et al. The functional role of fecal microbiota transplantation on Salmonella Enteritidis infection in chicks. Vet Microbiol 2022;269:109449. https://doi.org/10.1016/j.vetmic.2022.109449 
  3. Fesseha H, Demlie T, Mathewos M, Eshetu E. Effect of Lactobacillus species probiotics on growth performance of dual-purpose chicken. Vet Med (Auckl) 2021;12:75-83. https://doi.org/10.2147/vmrr.S300881 
  4. Hong Y, Zhou Z, Yu L, et al. Lactobacillus salivarius and Lactobacillus agilis feeding regulates intestinal stem cells activity by modulating crypt niche in hens. Appl Microbiol Biotechnol 2021;105:8823-35. https://doi.org/10.1007/s00253-021-11606-2 
  5. Kokoszynski D, Steczny K, Zochowska-Kujawska J, et al. Carcass characteristics, physicochemical properties, and texture and microstructure of the meat and internal organs of carrier and king pigeons. Animals (Basel) 2020;10:1315. https://doi.org/10.3390/ani10081315 
  6. Xu Q, Wang X, Liu Y, Dong X, Zou X. Parental dietary arachidonic acid altered serum fatty acid profile, hepatic antioxidant capacity, and lipid metabolism in domestic pigeons (Columba livia). Anim Sci J 2021;92:e13616. https://doi.org/10.1111/asj.13616 
  7. Pomianowski JF, Mikulski D, Pudyszak K, et al. Chemical composition, cholesterol content, and fatty acid profile of pigeon meat as influenced by meat-type breeds. Poult Sci 2009;88:1306-9. https://doi.org/10.3382/ps.2008-00217 
  8. Liu T, Wang L, Jiang X, Liu Y, Diao E, Xie P. Free-choice feeding of whole grains improves meat quality and intestinal development of pigeon squabs compared with complete pelleted feed. Life (Basel) 2023;13:848. https://doi.org/10.3390/life13030848 
  9. Ji F, Zhang D, Shao Y, et al. Changes in the diversity and composition of gut microbiota in pigeon squabs infected with Trichomonas gallinae. Sci Rep 2020;10:19978. https://doi.org/10.1038/s41598-020-76821-9 
  10. Wang X, Yan P, Feng S, et al. Identification and expression pattern analysis of miRNAs in pectoral muscle during pigeon (Columba livia) development. PeerJ 2021;9:e11438. https://doi.org/10.7717/peerj.11438 
  11. Ding J, Liao N, Zheng Y, et al. The composition and function of pigeon milk microbiota transmitted from parent pigeons to squabs. Front Microbiol 2020;11:1789. https://doi.org/10.3389/fmicb.2020.01789 
  12. Jin CL, He YA, Jiang SG, et al. Chemical composition of pigeon crop milk and factors affecting its production: a review. Poult Sci 2023;102:102681. https://doi.org/10.1016/j.psj.2023.102681 
  13. Ye M, Xu M, Chen C, et al. Expression analyses of candidate genes related to meat quality traits in squabs from two breeds of meat-type pigeon. J Anim Physiol Anim Nutr (Berl) 2018;102:727-35. https://doi.org/10.1111/jpn.12869 
  14. Chang L, Tang Q, Zhang R, et al. Evaluation of meat quality of local pigeon varieties in china. Animals (Basel) 2023;13:1291. https://doi.org/10.3390/ani13081291 
  15. Tsai CY, Hu SY, Santos HM, Catulin GEM, Tayo LL, Chuang KP. Probiotic supplementation containing Bacillus velezensis enhances expression of immune regulatory genes against pigeon circovirus in pigeons (Columba livia). J Appl Microbiol 2021;130:1695-704. https://doi.org/10.1111/jam.14893 
  16. Ge B, Yang H, Meng J, Chen X, Wang Z. Effects of mannan oligosaccharides and/or bifidobacterium on growth and immunity in domestic pigeon (Columba livia domestica). J Poult Sci 2020;57:277-83. https://doi.org/10.2141/jpsa.0190100 
  17. Zhao W, Liu Q, Jiang H, et al. Monitoring the variations in physicochemical characteristics of squab meat during the braising cooking process. Food Sci Nutr 2022;10:2727-35. https://doi.org/10.1002/fsn3.2876 
  18. Nichols RG, Davenport ER. The relationship between the gut microbiome and host gene expression: a review. Hum Genet 2021;140:747-60. https://doi.org/10.1007/s00439-020-02237-0 
  19. Qi R, Zhang Z, Wang J, et al. Introduction of colonic and fecal microbiota from an adult pig differently affects the growth, gut health, intestinal microbiota and blood metabolome of newborn piglets. Front Microbiol 2021;12:623673. https://doi.org/10.3389/fmicb.2021.623673 
  20. Ramirez GA, Keshri J, Vahrson I, et al. Cecal microbial hydrogen cycling potential is linked to feed efficiency phenotypes in chickens. Front Vet Sci 2022;9:904698. https://doi.org/10.3389/fvets.2022.904698 
  21. Bokoliya SC, Dorsett Y, Panier H, Zhou Y. Procedures for fecal microbiota transplantation in murine microbiome studies. Front Cell Infect Microbiol 2021;11:711055. https://doi.org/10.3389/fcimb.2021.711055 
  22. Sarrabayrouse G, Landolfi S, Pozuelo M, et al. Mucosal microbial load in Crohn's disease: a potential predictor of response to faecal microbiota transplantation. EBioMedicine 2020;51:102611. https://doi.org/10.1016/j.ebiom.2019.102611 
  23. Xu Q, Zhao W, Li Y, Zou X, Dong X. Intestinal immune development is accompanied by temporal deviation in microbiota composition of newly hatched pigeon squabs. Microbiol Spectr 2022;10:e0189221. https://doi.org/10.1128/spectrum.01892-21 
  24. Elokil AA, Chen W, Mahrose K, et al. Early life microbiota transplantation from highly feed-efficient broiler improved weight gain by reshaping the gut microbiota in laying chicken. Front Microbiol 2022;13:1022783. https://doi.org/10.3389/fmicb.2022.1022783 
  25. O'Callaghan J, O'Toole PW. Lactobacillus: host-microbe relationships. Curr Top Microbiol Immunol 2013;358:119-54. https://doi.org/10.1007/82_2011_187 
  26. Hao H, Zhang X, Tong L, et al. Effect of extracellular vesicles derived From Lactobacillus plantarum Q7 on gut microbiota and ulcerative colitis in mice. Front Immunol 2021;12:777147. https://doi.org/10.3389/fimmu.2021.777147 
  27. Ma S, Zhang F, Zhou F, et al. Metagenomic analysis reveals oropharyngeal microbiota alterations in patients with COVID-19. Signal Transduct Target Ther 2021;6:191. https://doi.org/10.1038/s41392-021-00614-3 
  28. Habib K, Drouillard J, de Aguiar Veloso V, Huynh G, Huynh V, Gragg SE. The use of probiotic megasphaera elsdenii as a pre-harvest intervention to reduce salmonella in finishing beef cattle: an in vitro model. Microorganisms 2022;10:1400. https://doi.org/10.3390/microorganisms10071400 
  29. Zhang X, Chen S, Zhang M, et al. Effects of fermented milk containing lacticaseibacillus paracasei strain shirota on constipation in patients with depression: a randomized, double-blind, placebo-controlled trial. Nutrients 2021;13:2238. https://doi.org/10.3390/nu13072238 
  30. Smith BJ, Miller RA, Ericsson AC, Harrison D, Strong R, Schmidt TM. Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice. BMC Microbiol 2019;19:130. https://doi.org/10.1186/s12866-019-1494-7 
  31. Huang R, Wu F, Zhou Q, et al. Lactobacillus and intestinal diseases: mechanisms of action and clinical applications. Microbiol Res 2022;260:127019. https://doi.org/10.1016/j.micres.2022.127019 
  32. Zhuge A, Li S, Lou P, et al. Longitudinal 16S rRNA sequencing reveals relationships among alterations of gut microbiota and nonalcoholic fatty liver disease progression in mice. Microbiol Spectr 2022;10:e0004722. https://doi.org/10.1128/spectrum.00047-22 
  33. Si J, Lee G, You HJ, et al. Gut microbiome signatures distinguish type 2 diabetes mellitus from non-alcoholic fatty liver disease. Comput Struct Biotechnol J 2021;19:5920-30. https://doi.org/10.1016/j.csbj.2021.10.032 
  34. Chung Y, Ryu Y, An BC, et al. A synthetic probiotic engineered for colorectal cancer therapy modulates gut microbiota. Microbiome 2021;9:122. https://doi.org/10.1186/s40168-021-01071-4 
  35. Dong L, Du H, Zhang M, et al. Anti-inflammatory effect of Rhein on ulcerative colitis via inhibiting PI3K/Akt/mTOR signaling pathway and regulating gut microbiota. Phytother Res 2022;36:2081-94. https://doi.org/10.1002/ptr.7429 
  36. Ghosh TS, Rampelli S, Jeffery IB, et al. Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries. Gut 2020;69:1218-28. https://doi.org/10.1136/gutjnl-2019-319654 
  37. Schoeler M, Caesar R. Dietary lipids, gut microbiota and lipid metabolism. Rev Endocr Metab Disord 2019;20:461-72. https://doi.org/10.1007/s11154-019-09512-0 
  38. Cai J, Sun L, Gonzalez FJ. Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis. Cell Host Microbe 2022;30:289-300. https://doi.org/10.1016/j.chom.2022.02.004 
  39. Bansal M, Fu Y, Alrubaye B, et al. A secondary bile acid from microbiota metabolism attenuates ileitis and bile acid reduction in subclinical necrotic enteritis in chickens. J Anim Sci Biotechnol 2020;11:37. https://doi.org/10.1186/s40104-020-00441-6 
  40. Collins SL, Patterson AD. The gut microbiome: an orchestrator of xenobiotic metabolism. Acta Pharm Sin B 2020;10:19-32. https://doi.org/10.1016/j.apsb.2019.12.001