대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
권호 표지
DOI QR코드

DOI QR Code

뇌출혈 환자의 피부약물 유해반응에 대한 가미승마갈근탕 치험 1례

A Case Report of Gamiseungmagalgeun-tang for a Cutaneous Adverse Drug Reaction in a Patient with Intracerebral Hemorrhage

  • 석은주 (동국대학교 일산한방병원 한방내과) ;
  • 홍정화 (동국대학교 일산한방병원 한방내과) ;
  • 이영주 (동국대학교 일산한방병원 한방내과) ;
  • 유재혁 (동국대학교 일산한방병원 한방내과) ;
  • 이진영 (동국대학교 일산한방병원 한방내과) ;
  • 최동준 (동국대학교 일산한방병원 한방내과)
  • Eun-joo Seok (Dept. of Internal Korean Medicine, Dong-Guk University Ilsan Oriental Medical Hospital) ;
  • Junghwa Hong (Dept. of Internal Korean Medicine, Dong-Guk University Ilsan Oriental Medical Hospital) ;
  • Youngju Rhee (Dept. of Internal Korean Medicine, Dong-Guk University Ilsan Oriental Medical Hospital) ;
  • Jae-hyuk You (Dept. of Internal Korean Medicine, Dong-Guk University Ilsan Oriental Medical Hospital) ;
  • Jin-young Lee (Dept. of Internal Korean Medicine, Dong-Guk University Ilsan Oriental Medical Hospital) ;
  • Dong-jun Choi (Dept. of Internal Korean Medicine, Dong-Guk University Ilsan Oriental Medical Hospital)
  • 투고 : 2024.04.28
  • 심사 : 2024.05.29
  • 발행 : 2024.05.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

A cutaneous adverse drug reaction (CADR) refers to an unexpected skin and mucosal reaction caused by drug administration. In the present case, a 65-year-old male presented with generalized itching and a maculopapular rash after taking Western medication, including anticonvulsants and a nonsteroidal anti-inflammatory drug (NSAID). He was treated with Gamiseungmagalgeun-tang, a traditional Korean herbal medicine. After treatment, the patient's symptoms improved, without recurrence. Based on this experience, traditional Korean herbal medicine, including Gamiseungmagalgeun-tang, may be beneficial for improving symptoms of CADRs.

키워드

참고문헌

  1. Lee EH, Jang YH. Cutaneous adverse drug reactions. J Korean Med Assoc 2023;66(1):41-7.  https://doi.org/10.5124/jkma.2023.66.1.41
  2. Park HK. Life-threatening Adverse Drug Reaction. Pharmacoepidemiology and Risk Management. 2011;4(2):53-7. 
  3. Lee JH. 약물에 의한 피부 이상반응. J Kor Soc Health-Syst Pharm 2015;32(1):1-7. 
  4. Nayak S, Acharjya B. Adverse cutaneous drug reaction. Indian J Dermatol 2008;53(1):2-8.  https://doi.org/10.4103/0019-5154.39732
  5. Arndt KA, Jick H. Rates of Cutaneous Reactions to Drugs. JAMA 1976;235(9):918-23.  https://doi.org/10.1001/jama.1976.03260350022021
  6. Michel DJ, Knodel LC. Comparison of three algorithms used to evaluate adverse drug reactions. American Journal of Hospital Pharmacy 1986;43(7):1709-14.  https://doi.org/10.1093/ajhp/43.7.1709
  7. Yoshio Y. Asakura internal medicine. 11th ed. Seoul: Wooriuihak; 2020, p. 510-4. 
  8. Choi YW. Drug Eruption. Ewha Med J 2012;35(2):76-82.  https://doi.org/10.12771/emj.2012.35.2.76
  9. Jung JA. Diagnosis and management of adverse drug reaction in the real world. Allergy Asthma Respir Dis 2023 Apr;11(2):53-5.  https://doi.org/10.4168/aard.2023.11.2.53
  10. Bigby M, Stern R. Cutaneous reactions to nonsteroidal anti-inflammatory drugs. A review. J Am Acad Dermatol 1985;12(5 Pt 1):866-76.  https://doi.org/10.1016/S0190-9622(85)70110-7
  11. Saha D, Begum SA, Sarkar S, Gupta N, Sen S, Kumar S. NSAIDS induced cutaneous adverse drug reaction-a case series. International Journal of Health and Clinical Research 2020;3(5):6-10. 
  12. Coombs PR. The classification of allergic reactions underlying disease. Clinical aspect of immunology 1962:317-37. 
  13. 전국한의과대학 피부외과학 교재편찬위원회. 한의피부외과학. busan: 선우; 2007, p. 366-9, 1272-85. 
  14. Jeong JC, Park SD, Kim HA. An Experimental Study on the Effect of Anti-Histamine of the Sungmagalkuntang and Sungmagalkuntang-plus-samultang. Dongguk Journal of the Institute of Oriental Medicine 1994;3(1):207-428. 
  15. Lyu JH, Lyu SA, Yoon HJ, KO WS. Anti-allergic Effect of Seungmagalgeuntang through Suppression of NF-κB and p38 Mitogen-Activated Protein KinaseActivation in the RBL-2H3 Cells. Korean J Oriental Physiology & Pathology 2008;22(6):1572-8. 
  16. Keum JH, Seo YS, Kang OH, Choi JG, Kwon DY. Anti-inflammatory effect of Seungmagalgeum -tang extract in human mast cells. Kor J Herbology 2013;28(5):7-11.  https://doi.org/10.6116/kjh.2013.28.5.7
  17. Park JG, Kang SH, Kang DW, Kim KS, Kim YB. Analysis of Korean Herbal Medicine Used in Case Studies of Treating Urticaria. J Korean Med Ophthalmol Otolaryngol Dermatol 2018;31(3):12-25. 
  18. Yoon JW, Yoon SW, Yoon HJ, Ko WS. The Clinical Study of Urticaria. J Korean Med Ophthalmol Otolaryngol Dermatol 2003;16(2):152-76. 
  19. Hong EG, Kim BH, Shin JH, Nam HJ, Kim KS. The Effect of Gamisungmagalguntang(加 味升麻葛根湯) on Chronic Urticaria Identified as "Wind Heat" Pattern. J Korean Med Ophthalmol Otolaryngol Dermatol 2013;26(4):60-9. https://doi.org/10.6114/jkood.2013.26.4.060