Journal of Korean Dental Science

Korean Academy of Dental Science (대한치의학회)
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Long-term Complications of Stevens-Johnson Syndrome on Permanent Teeth : A Case Report

  • Dabin Kim (Department of Pediatric Dentistry, School of Dentistry, Chosun University) ;
  • Myeongkwan Jih (Department of Pediatric Dentistry, School of Dentistry, Chosun University) ;
  • Nanyoung Lee (Department of Pediatric Dentistry, School of Dentistry, Chosun University)
  • Received : 2024.04.01
  • Accepted : 2024.05.22
  • Published : 2024.06.30
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Abstract

Stevens-Johnson syndrome (SJS) is a severe adverse cutaneous drug reaction seen rarely in clinical practice. Although relatively rare, the condition can be fatal. Mainly, it is caused by side effects of certain medications. Previous reports have associated Stevens-Johnson syndrome with abnormal root development, but the other long-term dental complications have rarely been reported. In this case, the patient developed SJS at the age of 5, and abnormal root development of the maxillary and mandibular first molars and mandibular incisors was observed, as well as impaction of the mandibular canine and enamel hypomineralization of multiple teeth. Accordingly, appropriate restorative treatment and orthodontic treatment were performed, and the clinical characteristics of this symptoms and its treatment were discussed in more detail. We aim to highlight the need for dentists to be aware of the potential dental complications of SJS and to enable early diagnosis and management of the condition to avoid undesirable sequelae.

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References

  1. Pavlos R, White KD, Wanjalla C, Mallal SA, Phillips EJ. Severe delayed drug reactions: role of genetics and viral infections. Immunol Allergy Clin North Am. 2017;37:785-815.
  2. Harr T, French LE. Toxic epidermal necrolysis and Stevens-Johnson syndrome. Orphanet J Rare Dis. 2010;5:39.
  3. Borchers AT, Lee JL, Naguwa SM, Cheema GS, Gershwin ME. Stevens-Johnson syndrome and toxic epidermal necrolysis. Autoimmun Rev. 2008;7:598-605.
  4. Magina S, Lisboa C, Leal V, Palmares J, Mesquita-Guimaraes J. Dermatological and ophthalmological sequels in toxic epidermal necrolysis. Dermatology. 2003;207:33-6.
  5. Yip LW, Thong BY, Lim J, Tan AW, Wong HB, Handa S, Heng WJ. Ocular manifestations and complications of Stevens-Johnson syndrome and toxic epidermal necrolysis: an Asian series. Allergy. 2007;62:527-31.
  6. Oplatek A, Brown K, Sen S, Halerz M, Supple K, Gamelli RL. Long-term follow-up of patients treated for toxic epidermal necrolysis. J Burn Care Res. 2006;27:26-33.
  7. De Man K. Abnormal root development, probably due to erythema multiforme (Stevens-Johnson syndrome). Int J Oral Surg. 1979;8:381-5.
  8. Ranalli DN, Elliott MA, Whaley TM, Campagna ED Jr. Stevens-Johnson syndrome: report of case with abnormal root development. ASDC J Dent Child. 1984;51:298-301.
  9. Brook U. Stevens-Johnson syndrome and abnormal root development: a case report. Int J Paediatr Dent. 1994;4:101-3.
  10. Roujeau JC, Kelly JP, Naldi L, Rzany B, Stern RS, Anderson T, Auquier A, Bastuji-Garin S, Correia O, Locati F, Mockenhaupt M, Paoletti C, Shapiro S, Shear N, Schopf E, Kaufman DW. Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. N Engl J Med. 1995;333:1600-7.
  11. Mockenhaupt M, Viboud C, Dunant A, Naldi L, Halevy S, Bavinck JNB, Sidoroff A, Schneck J, Roujeau JC, Flahault A. Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study. J Invest Dermatol. 2008;128:35-44.
  12. Lonjou C, Borot N, Sekula P, Ledger N, Thomas L, Halevy S, Naldi L, Bouwes-Bavinck JN, Sidoroff A, de Toma C, Schumacher M, Roujeau JC, Hovnanian A, Mockenhaupt M; RegiSCAR study group. A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs. Pharmacogenet Genomics. 2008;18:99-107.
  13. Bajaj N, Madan N, Rathnam A. Cessation in root development: Ramifications of' Stevens-Johnson' syndrome. J Indian Soc Pedod Prev Dent. 2012;30:267-70.
  14. Gaultier F, Rochefort J, Landru MM, Allanore L, Naveau A, Roujeau JC, Gogly B. Severe and unrecognized dental abnormalities after drug-induced epidermal necrolysis. Arch Dermatol. 2009;145:1332-3.
  15. Thornton JB, Worley SL. Short root anomaly in a patient with a history of Stevens-Johnson syndrome: report of case. ASDC J Dent Child. 1991;58:256-9.
  16. Fayle SA. Molar incisor hypomineralisation: restorative management. Eur J Paediatr Dent. 2003;4:121-6.
  17. Alaluusua S. Aetiology of molar-incisor hypomineralisation: a systematic review. Eur Arch Paediatr Dent. 2010;11:53-8.
  18. Alaluusua S, Lukinmaa PL, Vartiainen T, Partanen M, Torppa J, Tuomisto J. Polychlorinated dibenzo-p-dioxins and dibenzofurans via mother's milk may cause developmental defects in the child's teeth. Environ Toxicol Pharmacol. 1996;1:193-7.
  19. Crombie F, Manton D, Kilpatrick N. Aetiology of molar-incisor hypomineralization: a critical review. Int J Paediatr Dent. 2009;19:73-83.
  20. Jalevik B, Noren JG. Enamel hypomineralization of permanent first molars: a morphological study and survey of possible aetiological factors. Int J Paediatr Dent. 2000;10:278-89.
  21. Oliver RG, Mannion JE, Robinson JM. Morphology of the maxillary lateral incisor in cases of unilateral impaction of the maxillary canine. Br J Orthod. 1989;16:9-16.
  22. Jacoby H. The etiology of maxillary canine impactions. Am J Orthod. 1983;84:125-32.
  23. Brin I, Becker A, Shalhav M. Position of the maxillary permanent canine in relation to anomalous or missing lateral incisors: a population study. Eur J Orthod. 1986;8:12-6.
  24. Becker A, Smith P, Behar R. The incidence of anomalous maxillary lateral incisors in relation to palatally-displaced cuspids. Angle Orthod. 1981;51:24-9.
  25. Leaute-Labreze C, Lamireau T, Chawki D, Maleville J, Taieb A. Diagnosis, classification, and management of erythema multiforme and Stevens-Johnson syndrome. Arch Dis Child. 2000;83:347-52.
  26. Bajaj P, Sabharwal R, PK Mohammed R, Garg D, Kapoor C. Erythema multiforme: classification and immunopathogenesis. J Adv Med Dent Sci. 2013;1:40-7.