Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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A Case of Parotid Carcinoma Ex Pleomorphic Adenoma with Mixture of Malignant Subtypes

이하선에 발생한 혼합 아형의 암종들로 구성된 다형선종 유래 암종 1예

  • Youn Jin Cho (Department of Otorhinolaryngology-Head and Neck Surgery, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine) ;
  • Young Rok Jo (Department of Otorhinolaryngology-Head and Neck Surgery, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine) ;
  • Sang-Yeop Lee (Department of Pathology, International St. Mary's Hospital, Catholic Kwandong University College of Medicine) ;
  • Hye Ran Lee (Department of Otorhinolaryngology-Head and Neck Surgery, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine)
  • 조윤진 (가톨릭관동대학교 의과대학 국제성모병원 이비인후-두경부외과학교실) ;
  • 조영록 (가톨릭관동대학교 의과대학 국제성모병원 이비인후-두경부외과학교실) ;
  • 이상엽 (가톨릭관동대학교 의과대학 국제성모병원 병리과교실) ;
  • 이혜란 (가톨릭관동대학교 의과대학 국제성모병원 이비인후-두경부외과학교실)
  • Received : 2023.10.19
  • Accepted : 2024.01.01
  • Published : 2024.05.30
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Abstract

Carcinoma ex pleomorphic adenoma is an uncommon malignant salivary gland tumor that arises from a long-standing pleomorphic adenoma. The carcinomatous component of carcinoma ex pleomorphic adenoma can possess virtually any histologic subtype of salivary gland cancer. We experienced a case of a 61-year-old patient who presented with a right parotid mass that was initially palpated 20 years ago, with a sudden increase in size in the last few months. Radiological and cytological findings from fine needle aspiration biopsy could not exclude malignancy. Total parotidectomy and selective neck dissection were performed for treatment, and carcinoma ex pleomorphic adenoma with mixed carcinoma components of salivary duct carcinoma and myoepithelial carcinoma was diagnosed. After receiving postoperative radiation of 6000 cGy over 6 weeks, there has been no recurrence up to the 18-month follow-up. We report this rare case of carcinoma ex pleomorphic adenoma with mixed malignancy subtypes, accompanied by a review of literature.

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References

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