The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Cultivation, UHPLC Pattern Analysis, and Inhibitory Effect on Respiratory Inflammation of Lysimachia mauritiana Lam.

갯까치수염(Lysimachia mauritiana Lam.)의 재배 및 UHPLC 패턴 분석, 호흡기염증 억제 효과

  • Dong-Seon Kim (KM Science Research Division, KIOM) ;
  • Heung Joo Yuk (KM Science Research Division, KIOM) ;
  • JungMi Kim (Medicinal Crop team, Mungyeong Agricultural Technology Center) ;
  • Chaeseok Koh (Medicinal Crop team, Mungyeong Agricultural Technology Center) ;
  • Younjung Jang (Medicinal Crop team, Mungyeong Agricultural Technology Center) ;
  • Yoon-Young Sung (KM Science Research Division, KIOM)
  • 김동선 (한국한의학연구원 한의과학연구부) ;
  • 육흥주 (한국한의학연구원 한의과학연구부) ;
  • 김정미 (문경시농업기술센터 약용작물팀) ;
  • 고채석 (문경시농업기술센터 약용작물팀) ;
  • 장윤정 (문경시농업기술센터 약용작물팀) ;
  • 성윤영 (한국한의학연구원 한의과학연구부)
  • Received : 2024.04.09
  • Accepted : 2024.05.25
  • Published : 2024.05.30
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Abstract

Objectives : Lysimachia mauritiana Lam. is known as a medicinal plant native to Korea that has antioxidant, anticancer, antibacterial, and antiviral activities. However, until now, research on the cultivation technology of L. mauritiana is insufficient, and there are no research data on the systematic cultivation method and mass production of L. mauritiana. Therefore, this study aims to establish a cultivation system of L. mauritiana. Methods : The cultivation environment of open land and facilities according to the growth of L. mauritiana was compared and tested. In addition, the equivalence of the origin collection extract and the cultivation extract was evaluated through Ultra high performance liquid chromatography (UHPLC) patterns analysis according to cultivation and comparison of the effect of inhibiting respiratory inflammation using BEAS-2B human bronchial epithelial cells. Results : The cultivation technology system was established through cultivation research of L. mauritiana raw materials. In addition, as a result of comparing and evaluating the equivalence of cultivated plants and L. mauritiana raw materials for suppressing respiratory inflammation, the same results were confirmed, and the equivalence was confirmed as a result of analyzing the UHPLC pattern with L. mauritiana raw materials. Conclusions : This study suggests that extract from cultivation research of L. mauritiana plants, which are native to Korea, can be used as a health functional food or medicine to improve respiratory health.

Keywords

Acknowledgement

본 연구는 한국한의학연구원의 기본사업 '자생식물을 활용한 호흡기 건강 기능성 식품 소재 개발' 과제(과제번호 : KSN20234316)의 지원으로 이루어졌으며, 이에 감사드립니다.

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