Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Octacalcium phosphate, a promising bone substitute material: a narrative review

  • Received : 2023.01.04
  • Accepted : 2023.03.13
  • Published : 2024.01.31
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Abstract

Biomaterials have been used to supplement and restore function and structure by replacing or restoring parts of damaged tissues and organs. In ancient times, the medical use of biomaterials was limited owing to infection during surgery and poor surgical techniques. However, in modern times, the medical applications of biomaterials are diversifying owing to great developments in material science and medical technology. In this paper, we introduce biomaterials, focusing on calcium phosphate ceramics, including octacalcium phosphate, which has recently attracted attention as a bone graft material.

Keywords

Acknowledgement

This research was funded by a National Research Foundation of Korea Grant funded by the Korean Government (Ministry of Education; NRF-2017R1D1A3B03032090).

References

  1. Cohen J. Biomaterials in orthopedic surgery. Am J Surg 1967;114:31-41. https://doi.org/10.1016/0002-9610(67)90037-2
  2. National Institute of Health (NIH). Clinical applications of biomaterials: National Institute of Health Consensus Development Conference statement [Internet]. Bethesda, MD: NIH; 1982 [cited 2023 Jan 24]. https://consensus.nih.gov/1982/1982Biomaterials034html.htm.
  3. Williams DF; European Society for Biomaterials. Definitions in biomaterials: proceedings of a consensus conference of the European Society for Biomaterials, Chester, England, March 3-5, 1986. Amsterdam: Elsevier; 1987.
  4. Williams DF. The Williams dictionary of biomaterials. Liverpool: Liverpool University Press; 1999.
  5. Marin E, Boschetto F, Pezzotti G. Biomaterials and biocompatibility: an historical overview. J Biomed Mater Res A 2020;108:1617-33. https://doi.org/10.1002/jbm.a.36930
  6. Arnott R. Surgical practice in the prehistoric Aegean. Medizinhist J 1997;32:249-78.
  7. Bordenave G. Louis Pasteur (1822-1895). Microbes Infect 2003;5:553-60. https://doi.org/10.1016/S1286-4579(03)00075-3
  8. Newsom SW. Pioneers in infection control-Joseph Lister. J Hosp Infect 2003;55:246-53. https://doi.org/10.1016/j.jhin.2003.08.001
  9. Williams DF. On the mechanisms of biocompatibility. Biomaterials 2008;29:2941-53. https://doi.org/10.1016/j.biomaterials.2008.04.023
  10. Datta LP, Manchineella S, Govindaraju T. Biomolecules-derived biomaterials. Biomaterials 2020;230:119633.
  11. Basu B, Gowtham NH, Xiao Y, Kalidindi SR, Leong KW. Biomaterialomics: data science-driven pathways to develop fourth-generation biomaterials. Acta Biomater 2022;143:1-25. https://doi.org/10.1016/j.actbio.2022.02.027
  12. Enderle JD, Bronzino JD. Introduction to biomedical engineering. Amsterdam: Elsevier/Academic Press; 2012.
  13. Kargozar S, Ramakrishna S, Mozafari M. Chemistry of biomaterials: future prospects. Curr Opin Biomed Eng 2019;10:181-90. https://doi.org/10.1016/j.cobme.2019.07.003
  14. Yang K, Zhou C, Fan H, Fan Y, Jiang Q, Song P, et al. Bio-functional design, application and trends in metallic biomaterials. Int J Mol Sci 2017;19:24.
  15. Prasad K, Bazaka O, Chua M, Rochford M, Fedrick L, Spoor J, et al. Metallic biomaterials: current challenges and opportunities. Materials (Basel) 2017;10:884.
  16. Manivasagam G, Dhinasekaran D, Rajamanickam A. Biomedical implants: corrosion and its prevention-a review. Recent Patents Corros Sci 2010;2:40-54. https://doi.org/10.2174/1877610801002010040
  17. Szczesny G, Kopec M, Politis DJ, Kowalewski ZL, Lazarski A, Szolc T. A review on biomaterials for orthopaedic surgery and traumatology: from past to present. Materials (Basel) 2022;15:3622.
  18. Vallet-Regi M. Ceramics for medical applications. J Chem Soc Dalton Trans 2001;(2):97-108.
  19. Kenny SM, Buggy M. Bone cements and fillers: a review. J Mater Sci Mater Med 2003;14:923-38. https://doi.org/10.1023/A:1026394530192
  20. Goor OJ, Hendrikse SI, Dankers PY, Meijer EW. From supramolecular polymers to multi-component biomaterials. Chem Soc Rev 2017;46:6621-37. https://doi.org/10.1039/C7CS00564D
  21. Gribova V, Crouzier T, Picart C. A material's point of view on recent developments of polymeric biomaterials: control of mechanical and biochemical properties. J Mater Chem 2011;21: 14354-66. https://doi.org/10.1039/c1jm11372k
  22. Ko HF, Sfeir C, Kumta PN. Novel synthesis strategies for natural polymer and composite biomaterials as potential scaffolds for tissue engineering. Philos Trans A Math Phys Eng Sci 2010; 368:1981-97. https://doi.org/10.1098/rsta.2010.0009
  23. Leu Alexa R, Cucuruz A, Ghitulica CD, Voicu G, Stamat Balahura LR, Dinescu S, et al. 3D printable composite biomaterials based on GelMA and hydroxyapatite powders doped with cerium ions for bone tissue regeneration. Int J Mol Sci 2022;23:1841.
  24. Wei Q, Becherer T, Angioletti-Uberti S, Dzubiella J, Wischke C, Neffe AT, et al. Protein interactions with polymer coatings and biomaterials. Angew Chem Int Ed Engl 2014;53:8004-31. https://doi.org/10.1002/anie.201400546
  25. Yin W, Chen M, Bai J, Xu Y, Wang M, Geng D, et al. Recent advances in orthopedic polyetheretherketone biomaterials: material fabrication and biofunction establishment. Smart Mater Med 2022;3:20-36. https://doi.org/10.1016/j.smaim.2021.11.005
  26. Rehman M, Madni A, Webster TJ. The era of biofunctional biomaterials in orthopedics: what does the future hold? Expert Rev Med Devices 2018;15:193-204. https://doi.org/10.1080/17434440.2018.1430569
  27. Bryers JD, Giachelli CM, Ratner BD. Engineering biomaterials to integrate and heal: the biocompatibility paradigm shifts. Biotechnol Bioeng 2012;109:1898-911. https://doi.org/10.1002/bit.24559
  28. Helmus MN, Gibbons DF, Cebon D. Biocompatibility: meeting a key functional requirement of next-generation medical devices. Toxicol Pathol 2008;36:70-80. https://doi.org/10.1177/0192623307310949
  29. Balamurugan A, Rajeswari S, Balossier G, Rebelo AH, Ferreira JM. Corrosion aspects of metallic implants: an overview. Mater Corros 2008;59:855-69. https://doi.org/10.1002/maco.200804173
  30. Harrington RE, Guda T, Lambert B, Martin J. Sterilization and disinfection of biomaterials for medical devices. In: Wagner WR, Sakiyama-Elbert SE, Zhang G, Yaszemski MJ, editors. Biomaterials science. 4th ed. Cambridge: Academic Press; 2020. p. 1431-46.
  31. Sukumaran VG, Bharadwaj N. Ceramics in dental applications. Trends Biomater Artif Organs 2006;20:7-12.
  32. DeGarmo EP, Black JT, Kohser RA. DeGarmo's materials and processes in manufacturing. 12th ed. Hoboken, NJ: John Wiley & Sons; 2017.
  33. Kumar P, Dehiya BS, Sindhu A. Bioceramics for hard tissue engineering applications: a review. Int J Appl Eng Res 2018;13: 2744-52.
  34. Best SM, Porter AE, Thian ES, Huang J. Bioceramics: past, present and for the future. J Eur Ceram Soc 2008;28:1319-27. https://doi.org/10.1016/j.jeurceramsoc.2007.12.001
  35. Dorozhkin SV. Calcium orthophosphates as bioceramics: state of the art. J Funct Biomater 2010;1:22-107. https://doi.org/10.3390/jfb1010022
  36. Vallet-Regi M, Gonzalez-Calbet JM. Calcium phosphates as substitution of bone tissues. Prog Solid State Chem 2004;32:1-31. https://doi.org/10.1016/j.progsolidstchem.2004.07.001
  37. Samavedi S, Whittington AR, Goldstein AS. Calcium phosphate ceramics in bone tissue engineering: a review of properties and their influence on cell behavior. Acta Biomater 2013; 9:8037-45. https://doi.org/10.1016/j.actbio.2013.06.014
  38. Hajiali F, Tajbakhsh S, Shojaei A. Fabrication and properties of polycaprolactone composites containing calcium phosphate-based ceramics and bioactive glasses in bone tissue engineering: a review. Polym Rev 2018;58:164-207. https://doi.org/10.1080/15583724.2017.1332640
  39. Gaharwar AK, Cross LM, Peak CW, Gold K, Carrow JK, Brokesh A, et al. 2D Nanoclay for biomedical applications: regenerative medicine, therapeutic delivery, and additive manufacturing. Adv Mater 2019;31:e1900332.
  40. Alge DL, Santa Cruz G, Goebel WS, Chu TM. Characterization of dicalcium phosphate dihydrate cements prepared using a novel hydroxyapatite-based formulation. Biomed Mater 2009;4:025016.
  41. Cacciotti I. Cationic and anionic substitutions in hydroxyapatite. In: Antoniac I, editor. Handbook of bioceramics and biocomposites. Berlin: Springer; 2016. p. 145-211.
  42. Fu Q, Saiz E, Rahaman MN, Tomsia AP. Toward strong and tough glass and ceramic scaffolds for bone repair. Adv Funct Mater 2013;23:5461-76. https://doi.org/10.1002/adfm.201301121
  43. Carrodeguas RG, De Aza S. α-Tricalcium phosphate: synthesis, properties and biomedical applications. Acta Biomater 2011;7:3536-46. https://doi.org/10.1016/j.actbio.2011.06.019
  44. Bohner M, Santoni BLG, Dobelin N. β-tricalcium phosphate for bone substitution: synthesis and properties. Acta Biomater 2020;113:23-41. https://doi.org/10.1016/j.actbio.2020.06.022
  45. Wang L, Nancollas GH. Calcium orthophosphates: crystallization and dissolution. Chem Rev 2008;108:4628-69. https://doi.org/10.1021/cr0782574
  46. Combes C, Rey C. Amorphous calcium phosphates: synthesis, properties and uses in biomaterials. Acta Biomater 2010;6:3362-78. https://doi.org/10.1016/j.actbio.2010.02.017
  47. Brown WE, Schroeder LW, Ferris JS. Interlayering of crystalline octacalcium phosphate and hydroxylapatite. J Phys Chem 1979;83:1385-8. https://doi.org/10.1021/j100474a006
  48. Black JD, Tadros BJ. Bone structure: from cortical to calcium. Orthop Trauma 2020;34:113-9. https://doi.org/10.1016/j.mporth.2020.03.002
  49. Mathew M, Takagi S. Structures of biological minerals in dental research. J Res Natl Inst Stand Technol 2001;106:1035-44. https://doi.org/10.6028/jres.106.054
  50. Suzuki O. Octacalcium phosphate: osteoconductivity and crystal chemistry. Acta Biomater 2010;6:3379-87. https://doi.org/10.1016/j.actbio.2010.04.002
  51. Kim J, Kim S, Song I. Biomimetic octacalcium phosphate bone has superior bone regeneration ability compared to xenogeneic or synthetic bone. Materials (Basel) 2021;14:5300.
  52. Suzuki O, Shiwaku Y, Hamai R. Octacalcium phosphate bone substitute materials: comparison between properties of biomaterials and other calcium phosphate materials. Dent Mater J 2020;39:187-99. https://doi.org/10.4012/dmj.2020-001
  53. Kawai T, Anada T, Honda Y, Kamakura S, Matsui K, Matsui A, et al. Synthetic octacalcium phosphate augments bone regeneration correlated with its content in collagen scaffold. Tissue Eng Part A 2009;15:23-32. https://doi.org/10.1089/ten.tea.2008.0141
  54. Sakai S, Anada T, Tsuchiya K, Yamazaki H, Margolis HC, Suzuki O. Comparative study on the resorbability and dissolution behavior of octacalcium phosphate, β-tricalcium phosphate, and hydroxyapatite under physiological conditions. Dent Mater J 2016;35:216-24. https://doi.org/10.4012/dmj.2015-255
  55. Kamakura S, Sasano Y, Shimizu T, Hatori K, Suzuki O, Kagayama M, et al. Implanted octacalcium phosphate is more resorbable than beta-tricalcium phosphate and hydroxyapatite. J Biomed Mater Res 2002;59:29-34. https://doi.org/10.1002/jbm.1213
  56. Anada T, Kumagai T, Honda Y, Masuda T, Kamijo R, Kamakura S, et al. Dose-dependent osteogenic effect of octacalcium phosphate on mouse bone marrow stromal cells. Tissue Eng Part A 2008;14:965-78. https://doi.org/10.1089/ten.tea.2007.0339
  57. Shiwaku Y, Tsuchiya K, Xiao L, Suzuki O. Effect of calcium phosphate phases affecting the crosstalk between osteoblasts and osteoclasts in vitro. J Biomed Mater Res A 2019;107:1001-13. https://doi.org/10.1002/jbm.a.36626
  58. Kamakura S, Sasaki K, Honda Y, Masuda T, Anada T, Kawai T, et al. Differences of bone regeneration by various calcium phosphate/collagen composites. Key Eng Mater 2008;361-3:1229-32. https://doi.org/10.4028/www.scientific.net/KEM.361-363.1229
  59. Kawai T, Echigo S, Matsui K, Tanuma Y, Takahashi T, Suzuki O, et al. First clinical application of octacalcium phosphate collagen composite in human bone defect. Tissue Eng Part A 2014;20: 1336-41. https://doi.org/10.1089/ten.tea.2013.0508
  60. Kim JS, Jang TS, Kim SY, Lee WP. Octacalcium phosphate bone substitute (Bontree®): from basic research to clinical case study. Appl Sci 2021;11:7921.
  61. Parida P, Behera A, Mishra SC. Classification of biomaterials used in medicine. Int J Adv Appl Sci 2012;1:31-5. 12 https://doi.org/10.12701/jyms.2023.00010