Journal of Ginseng Research

  • 제48권3호
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  • Pages.341-345
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  • 2024
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  • 1226-8453(pISSN)
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  • 2093-4947(eISSN)
고려인삼학회 (The Korean Society of Ginseng)
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Gintonin upregulates cytokine production and expression of NKp30, NKp44 and NKp44 related to natural killer cell activity on immunosuppressive rat

  • BaiCheng Chen (College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University) ;
  • Ajay Vijayakumar (College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University) ;
  • Chul Park (College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University) ;
  • Ulsoo Choi (College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University) ;
  • Seung-Yeol Nah (Ginsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University) ;
  • Jong-Hoon Kim (College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University)
  • 투고 : 2023.09.06
  • 심사 : 2023.12.06
  • 발행 : 2024.05.01
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초록

The objective of the study is to estimate the potential of gintonin, as an immune enhancing agent through natural killer cell (NK cell) activity in cyclophosphamide (CY)-induced immunosuppressive animals. Accumulated results reveals that, gintonin attenuated CY-induced immunosuppression and it might modulate NK cell activity to boost the immunity.

키워드

과제정보

This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Education (2020R1l1A3072212) and by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT, 2023R1A2C1003481).

참고문헌

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