Journal of Ginseng Research

  • 제48권3호
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  • Pages.286-297
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  • 2024
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  • 1226-8453(pISSN)
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  • 2093-4947(eISSN)
고려인삼학회 (The Korean Society of Ginseng)
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Brain plasticity and ginseng

  • Myoung-Sook Shin (College of Korean Medicine, Gachon University) ;
  • YoungJoo Lee (Department of Integrative Bioscience and Biotechnology, College of Life Science, Sejong University) ;
  • Ik-Hyun Cho (Department of Convergence Medical Science, College of Korean Medicine, Kyung Hee University) ;
  • Hyun-Jeong Yang (Department of Integrative Bioscience, University of Brain Education)
  • 투고 : 2023.11.15
  • 심사 : 2024.03.21
  • 발행 : 2024.05.01
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⟨ 이전 논문 다음 논문 ⟩

초록

Brain plasticity refers to the brain's ability to modify its structure, accompanied by its functional changes. It is influenced by learning, experiences, and dietary factors, even in later life. Accumulated researches have indicated that ginseng may protect the brain and enhance its function in pathological conditions. There is a compelling need for a more comprehensive understanding of ginseng's role in the physiological condition because many individuals without specific diseases seek to improve their health by incorporating ginseng into their routines. This review aims to deepen our understanding of how ginseng affects brain plasticity of people undergoing normal aging process. We provided a summary of studies that reported the impact of ginseng on brain plasticity and related factors in human clinical studies. Furthermore, we explored researches focused on the molecular mechanisms underpinning the influence of ginseng on brain plasticity and factors contributing to brain plasticity. Evidences indicate that ginseng has the potential to enhance brain plasticity in the context of normal aging by mediating both central and peripheral systems, thereby expecting to improve age-related declines in brain function. Moreover, given modern western diet can damage neuroplasticity in the long term, ginseng can be a beneficial supplement for better brain health.

키워드

과제정보

This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2020R1I1A3A04038150) to H.J.Yang and a grant of the Basic Science Research Program through the National Research Foundation (NRF) funded by the Ministry of Science, and ICT, Republic of Korea (NRF-2022R1A2C2009817) to I. H. Cho.

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