Anxiety and mood (대한불안의학회지)

Korean Academy of Anxiety Disorders (대한불안의학회)
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Does a Frontal 2-Electrode Electroencephalogram Provide Sufficient Neuropsychological Information in Various Major Psychiatric Disorders?

  • Sol Han (Department of Psychiatry, Ilsan Paik Hospital, Inje University) ;
  • Hyen-Ho Hwang (Clinical Emotion and Cognition Research Laboratory, Inje University) ;
  • Kang-Min Choi (Clinical Emotion and Cognition Research Laboratory, Inje University) ;
  • Sungkean Kim (Department of Human-Computer Interaction, Hanyang University) ;
  • Seung-Hwan Lee (Department of Psychiatry, Ilsan Paik Hospital, Inje University)
  • Received : 2023.12.27
  • Accepted : 2024.03.29
  • Published : 2024.04.30
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Abstract

Objective : The purpose of this study is to compare the signal obtained from the frontal 2-electrodes EEG with that obtained from the temporal, central, and parietal 2 electrodes. Methods : EEGs were recorded in a total of 67 patients with major depressive disorder (MDD), 104 patients with schizophrenia (SCZ), and 29 patients with Alzheimer's disease (AD). For each disease group, there were healthy controls (HC) that were paired accordingly (HC1=69, HC2=104, HC3=27). The following measurements were compared across electrodes: band power, alpha peak frequency (APF), APF power, alpha asymmetry (AA), and Kolmogorov complexity (KC). Results : Statistically significant differences were found in band power measured from frontal electrodes compared to electrodes placed in other locations. Specifically, the power of theta waves was measured higher in the temporal electorodes, alpha 1 and alpha 2 waves in the parietal, beta 1 and beta 2 in the central, and gamma waves in the temporal electrodes. Both SCZ and AD patients showed increased theta power in all electrodes. In SCZ patients, APF decreased in the central and temporal electrodes, but the APF power analysis showed no difference between the patients and controls. Additionally, AD patients exhibited increased AA in the central EEG, while SCZ patients showed decreased KC in the parietal and temporal electrodes. Conclusion : Depending on the electrode location, sensitive EEG frequencies differed. Compared with signals from other electrodes, frontal EEG in MDD patients revealed generally constant signal values, though the temporo-parieto-central electrodes appeared to be more reliable in SCZ and AD patients.

Keywords

Acknowledgement

We would like to thank all individuals who directly or indirectly contributed to this research.

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