한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제41권2호
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  • Pages.117-122
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  • 2024
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
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Successful Treatment of Feline Nasopharyngeal Lymphoma by Hypofractionated Radiation Therapy After Surgical Debulking in a Cat

  • Sumin Kim (Institute of Animal Medicine, Department of Veterinary Medicine Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Gunha Hwang (Institute of Animal Medicine, Department of Veterinary Medicine Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Jin-Yoo Kim (Institute of Animal Medicine, Department of Veterinary Medicine Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Chi-Oh Yun (Institute of Animal Medicine, Department of Veterinary Medicine Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Seunghwa Lee (Institute of Animal Medicine, Department of Veterinary Medicine Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Moonyeong Choi (Yangsan S Animal Cancer Center) ;
  • Joong-Hyun Song (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Hee Chun Lee (Institute of Animal Medicine, Department of Veterinary Medicine Imaging, College of Veterinary Medicine, Gyeongsang National University) ;
  • Tae Sung Hwang (Institute of Animal Medicine, Department of Veterinary Medicine Imaging, College of Veterinary Medicine, Gyeongsang National University)
  • 투고 : 2024.03.03
  • 심사 : 2024.03.20
  • 발행 : 2024.04.30
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초록

A 3-year-old spayed female Russian blue cat was presented for dyspnea, nasal discharge, and stertorous breathing. Plain thoracic radiography revealed no specific findings. Computed tomography (CT) was performed to differentiate upper airway tract disorders. It revealed the presence of an iso-attenuating mass measuring 10.0 × 7.9 × 15.6 mm, with mild homogeneous contrast enhancement occupying the rostral nasopharynx. The mass was surgically debulked via a longitudinal incision in the soft palate. Histopathological and immunohistochemistry analysis of the surgically excised mass revealed CD3-/CD79a+ B cell lymphoma with an incomplete margin. The patient underwent hypofractionated radiation therapy, receiving a total of 36 Gray (Gy) in 6 Gy fractions over a six-week period. A follow-up CT examination was performed after 27 months of irradiation and the patient was confirmed to have achieved a complete response. There were no complications related to irradiation. The patient was alive for 40 months without recurrence. This study suggests that hypofractionated radiation therapy combined with surgical debulking could be considered as a treatment option for feline nasopharyngeal lymphoma.

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과제정보

This work was supported by the research grant of the Gyeongsang National University in 2023.

참고문헌

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