전자통신동향분석 (Electronics and Telecommunications Trends)

한국전자통신연구원 (Electronics and Telecommunications Research Institute)
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MEA 기반 신경제약 스크리닝 기술 개발 동향

Trends in MEA-based Neuropharmacological Drug Screening

  • 김용희 (사이버브레인연구실) ;
  • 정상돈 (사이버브레인연구실)
  • Y.H. Kim ;
  • S.D. Jung
  • 발행 : 2023.02.01
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초록

The announcement of the US Environmental Protection Agency that it will stop conducting or funding experimental studies on mammals by 2035 should prioritize ongoing efforts to develop and use alternative toxicity screening methods to animal testing. Toxicity screening is likely to be further developed considering the combination of human-induced pluripotent-stem-cell-derived organ-on-a-chip and multielectrode array (MEA) technologies. We briefly review the current status of MEA technology and MEA-based neuropharmacological drug screening using various cellular model systems. Highlighting the coronavirus disease pandemic, we shortly comment on the importance of early prediction of toxicity by applying artificial intelligence to the development of rapid screening methods.

키워드

과제정보

본 연구는 한국전자통신연구원 연구운영비지원사업의 일환으로 수행되었음[22ZB1160, ICT 창의기술 개발].

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