The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
권호 표지
DOI QR코드

DOI QR Code

Management of Steroid Rebound Phenomenon in Patients with Eczema

습진 환자의 스테로이드제 반동 현상 관리 및 치험 1례

  • So-Eun Son (Department of Korean Ophthalmology, Otolaryngology & Dermatology, College of Korean Medicine, Dongshin University) ;
  • Hye-Jin Park (Department of Korean Ophthalmology, Otolaryngology & Dermatology, College of Korean Medicine, Dongshin University) ;
  • Song Choi (Department of Internal Korean Medicine, Mokpo Korean Medicine Hospital, Dongshin University) ;
  • Min-Yeong Jung (Department of Korean Ophthalmology, Otolaryngology & Dermatology, College of Korean Medicine, Dongshin University)
  • 손소은 (동신대학교 한의과대학 한방안이비인후피부과학교실) ;
  • 박혜진 (동신대학교 한의과대학 한방안이비인후피부과학교실) ;
  • 최송 (동신대학교 한방병원 한방내과) ;
  • 정민영 (동신대학교 한의과대학 한방안이비인후피부과학교실)
  • Received : 2023.10.10
  • Accepted : 2023.11.07
  • Published : 2023.11.25
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives : We would like to report what symptoms appear in patients experiencing steroid rebound phenomenon and how to manage and treat them at Korean medicine hospital. Methods : A 20-year-old woman who had been using topical and oral steroids for more than 6 weeks presented to the hospital. She hospitalized for 5 weeks and stopped using steroid. The treatment applied was acupuncture, wet dressing therapy and herbal medicine including Yangdokbackho-tang, Sunbangpaedok-tang and Danguieumja. We assessed symptoms through Inflammation Index and Chronicization Index. Results : Right after she stopped using steroid, symptoms of skin got worse gradually. However, after 5 weeks of treatment, all symptoms except itching and dryness disappeared. When symptom was severe, Inflammation Index and Chronicization Index was 12 and 9 points and after the treatment they were 2 and 4 points. Conclusions : This study shows various symptoms in patients with topical steroid addiction and how to manage at Korean medicine hospital.

Keywords

References

  1. Steroid. Korea pharmaceutical information center drug encyclopedia. 2022[cited 2023 OCT 6]. Available from:https://www.health.kr/researchInfo/encyclopedia.asp
  2. NEO handbook. NEO intern handbook. 2nd ed. Paju:Koonja. 2021:461-8.
  3. Lee SC. Dermatological drugs and therapies. Seoul:Medbook. 2018:12-101.
  4. Fukaya M, Sato K, Sato M, Kimata H, Fujisawa S, Dozono H, et al. Topical steroid addiction in atopic dermatitis. Drug Healthc Patient Saf. 2014;6:131-8. https://doi.org/10.2147/DHPS.S69201
  5. Yoon JG. Hanui pibu jillyo cheot georeum. Paju:Koonja. 2019:122-4.
  6. Hodgens A, Sharman T. Corticosteroids. StatPearls[Internet]. 2023[cited 2023 OCT 6]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554612/
  7. Hajar T, Leshem YA, Hanifin JM, Nedorost ST, Lio PA, Paller AS, et al. A systematic review of topical corticosteroid withdrawal ("steroid addiction") in patients with atopic dermatit is and other dermatoses. J Am Acad Dermatol. 2015;72(3):541-9. https://doi.org/10.1016/j.jaad.2014.11.024
  8. Tan SY, Chandran NS, Choi EC. Steroid Phobia: Is There a Basis? A Review of Topical Steroid Safety, Addiction and Withdrawal. Clin Drug Investig. 2021;41(10):835-42. https://doi.org/10.1007/s40261-021-01072-z
  9. Wahab F, Rahman RA, Yaacob LH, Noor NM, Draman N. A Case Report of Steroid Withdrawal Syndrome. Korean J Fam Med. 2020;41(5):359-62. https://doi.org/10.4082/kjfm.18.0181
  10. Kim DH, Park SJ, Jung JY, Kim SC, Byun SH. Anti-inflammatory Effects of the Aqueous Extract of Hwangnyeonhaedok-tang in LPS-activated Macrophage Cells. The Korea Journal of Herbology. 2009;24(4):39-47.
  11. Isohama Y, Horie I. Pharmacological rationality of chronic subdural hematoma treatment with goreisan. Farumashia. 2018;54(2):139-43.
  12. Jo SJ, Kim CY, Ha UR, Kwon K. Two Case Reports on Atopic Dermatitis with Rebound Phenomena after Steroid Interruption. J Korean Med Ophthalmol Otolaryngol Dermatol. 2021;34(1):101-11.
  13. Shin SH, Yun JM, Heo JE, Ko WS, Yoon HJ. A Case Study on Steroid Rebound Phenomenon after Steroids Treatment for Pompholyx. JKorean Med Ophthalmol Otolaryngol Dermatol. 2014;27(3):155-61. https://doi.org/10.6114/jkood.2014.27.3.155
  14. Han CY, Kim JD, Kang DW, Kim KS, Kim YB. Review about using Herbal medicine on steroid tapering and steroid overuse in Skin disease. J Korean Med Ophthalmol Otolaryngol Dermatol. 2020;33(3):115-24.