Journal of Korean Biological Nursing Science

  • 제25권4호
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  • Pages.285-294
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  • 2023
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  • 2383-6415(pISSN)
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  • 2383-6423(eISSN)
한국기초간호학회 (Korean society of Biological Nursing Science)
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중소병원으로 전원 온 환자의 카바페넴내성장내세균속균종 보균 위험요인

Risk factors for the colonization of carbapenem-resistant Enterobacteriaceae in patients transferred to a small/medium-size hospital in Korea: a retrospective study

  • 이미선 (한림대학교 간호대학원) ;
  • 김현정 (한림대학교 간호대학, 간호학연구소)
  • Misun Lee (Graduate School of Nursing Science, Hallym University) ;
  • Hyunjung Kim (School of Nursing, Research Institute of Nursing Science, Hallym University)
  • 투고 : 2023.10.13
  • 심사 : 2023.11.12
  • 발행 : 2023.11.30
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초록

Purpose: This study aimed to identify the colonization rate of carbapenem-resistant Enterobacteriaceae (CRE), the characteristics of CRE isolates, and risk factors for CRE colonization in patients transferred to the general wards of a small/medium-sized hospital. Methods: This retrospective study was conducted on patients who underwent CRE culture tests within 24 hours of admission among patients transferred to a small/medium-sized hospital. Forty-seven patients confirmed as positive for CRE were classified as belonging to the patient group. For the control group, 235 patients (five times the number of the patient group) were matched by sex, age, and diagnosis, and then selected at random. Data were analyzed using descriptive analysis and multiple logistic regression analysis. Results: The CRE colonization rate was 5% (47 out of 933 patients), and Klebsiella pneumoniae (68.0%) was the most common isolate of CRE. The positivity rate of carbapenemase-producing Enterobacteriaceae was 61.7%. The risk factors for CRE colonization included renal disease (odds ratio [OR]=4.93; 95% confidence interval [CI], 1.49-16.31), heart disease (OR=3.86; 95% CI, 1.35-11.01), indwelling urinary catheters (OR=4.43; 95% CI, 1.59-12.36), and cephalosporin antibiotic use (OR=8.57; 95% CI, 1.23-59.60). Conclusion: Having a comorbid renal or cardiac disease, an indwelling urinary catheter, or a history of exposure to cephalosporin antibiotics could be classified as risk factors for CRE colonization in patients transferred to small and medium-size hospitals. It is necessary to perform active infection control through proactive CRE culture testing of patients with risk factors.

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