Acknowledgement
This work was supported by the National Research Foundation of Korea (NRF), funded by the Ministry of Science and ICT (No. 2022R1A5A2029546 and 2021R1A2C2007041), a Korea University Grant, and the Institute of Biomedical Science and Food Safety, CJ-Korea University Food Safety Hall at Korea University, Republic of Korea.
References
- Guo M, Peng J, Huang X, Xiao L, Huang F, Zuo Z. 2021. Gut microbiome features of chinese patients newly diagnosed with Alzheimer's disease or mild cognitive impairment. J. Alzheimer's Dis. 80: 299-310. https://doi.org/10.3233/JAD-201040
- Lopez OL. 2013. Mild cognitive impairment. Continuum (Minneap Minn) 19: 411-424. https://doi.org/10.1212/01.CON.0000429175.29601.97
- Ejtahed HS, Soroush AR, Angoorani P, Larijani B, Hasani-Ranjbar S. 2016. Gut microbiota as a target in the pathogenesis of metabolic disorders: a new approach to novel therapeutic agents. Horm. Metab. Res. 48: 349-358. https://doi.org/10.1055/s-0042-107792
- Ejtahed HS, Angoorani P, Hasani-Rabjbar S, Siadat SD, Ggasemi N, Larijani B, et al. 2018. Adaptation of human gut microbiota to bariatric surgeries in morbidly obese patients: a systematic review. Microb. Pathog. 116: 13-21. https://doi.org/10.1016/j.micpath.2017.12.074
- Ejtahed HS, Angoorani P, Soroush AR, Ahmad R, Siadat SD, Shirzad N, Hasani RS, et al. 2020. Our little friends with big roles: alterations of the gut microbiota in thyroid disorders. Endocr. Metab. Immune. Disord. Drug Targets. 20: 344-350. https://doi.org/10.2174/1871530319666190930110605
- Barrio C, S AS, I MM. 2021. The gut microbiota-brain axis, psychobiotics and its influence on brain and behaviour: a systematic review. Psychoneuroendocrinology 137: 105640.
- Alsegiani AS, Shah ZA. 2022. The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline. Neural. Regen. Res. 17: 2407.
- Saji N, Murotani K, Hisada T, Tsuduki T, Sugimoto T, Kimura A, et al. 2019. The relationship between the gut microbiome and mild cognitive impairment in patients without dementia: a cross-sectional study conducted in Japan. Sci. Rep. 9: 1-10. https://doi.org/10.1038/s41598-018-37186-2
- Jiang J, Liu H, Wang Z, Tian H, Wang S, Yang J, et al. 2021. Electroacupuncture could balance the gut microbiota and improve the learning and memory abilities of Alzheimer's disease animal model. PLoS One 16: e0259530.
- Byrd DA, Carson TL, Williams F, Vogtmann E. 2020. Elucidating the role of the gastrointestinal microbiota in racial and ethnic health disparities. Genome Biol. 21: 192.
- Schnorr SL, Candela M, Rampelli S, Centanni M, Consolandi C, Basaglia G, et al. 2014. Gut microbiome of the Hadza hunter-gatherers. Nat. Commun. 5: 3654.
- Dwiyanto J, Hussain MH, Reidpath D, O KS, Oasim A, Lee SWH, et al. 2021. Ethnicity influences the gut microbiota of individuals sharing a geographical location: a cross-sectional study from a middle-income country. Sci. Rep. 11: 1-10. https://doi.org/10.1038/s41598-020-79139-8
- Gupta VK, S Paul, C D. 2017. Geography, ethnicity or subsistence-specific variations in human microbiome composition and diversity. Front. Microbiol. 8: 1162.
- Brooks AW, Priya S, Blekhman R, Bordenstein SR. 2018. Gut microbiota diversity across ethnicities in the United States. PLoS Biol. 16: e2006842.
- Goyal S, Farhana L, Antaki F, Judd S, Nangia MP, Hadden T, et al. 2016. Colorectal cancer and racial disparity: gut microbiome as a potential regulator 138. Am. J. Gastroenterol. Suppl. 111: S66.
- Carson TL, Wang F, Cui X, Jackson BE, Van Der Pol W, Lefkowitz EJ, et al. 2018. Associations between race, perceived psychological stress, and the gut microbiota in a sample of generally healthy black and white women: a pilot study on the role of race and perceived psychological stress. Psychosom. Med. 80: 640.
- Pulikkan JP, Maji A, Dhakan DB, Saxena R, Mohan B, Anto MM, et al. 2018. Gut microbial dysbiosis in Indian children with autism spectrum disorders. Microb. Ecol. 76: 1102-1114. https://doi.org/10.1007/s00248-018-1176-2
- Yang Y, Zheng W, Cai Q, Shrubsole MJ, Pei Z, Brucker R, et al. 2019. Racial differences in the oral microbiome: data from low-income populations of African ancestry and European ancestry. Msystems 4: e00639-19.
- Verhaar BJ, Collard D, Prodan A, Levels JHM, Zwinderman AH, Backhed F, et al. 2020. Associations between gut microbiota, faecal short-chain fatty acids, and blood pressure across ethnic groups: the HELIUS study. Eur Heart J. 41: 4259-4267. https://doi.org/10.1093/eurheartj/ehaa704
- Liu P, Wu L, Peng G, Han Y, Tang R, Ge J, et al. 2019. Altered microbiomes distinguish Alzheimer's disease from amnestic mild cognitive impairment and health in a Chinese cohort. Brain Behav. Immun. 80: 633-643. https://doi.org/10.1016/j.bbi.2019.05.008
- Guo M, Jun P, Xiaoyan H, Lingjun X, Fenyan H, Zhiyi Z. 2021. Gut microbiome features of Chinese patients newly diagnosed with Alzheimer's disease or mild cognitive impairment. J. Alzheimer's Dis. 80: 299-310. https://doi.org/10.3233/JAD-201040
- Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJA, Holmes SP. 2016. DADA2: high-resolution sample inference from Illumina amplicon data. Nat. Methods 13: 581-583. https://doi.org/10.1038/nmeth.3869
- Glockner FO, Yilmaz P, Quast C, Gerken J, Beccati A, Ciuprina A, et al. 2017. 25 years of serving the community with ribosomal RNA gene reference databases and tools. J. Biotechnol. 261: 169-176. https://doi.org/10.1016/j.jbiotec.2017.06.1198
- Bolyen E, Rideout JR, Dillon MR, Bokulich NA, Abnet CC, Ghalith GA, et al. 2019. Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2. Nat. Biotechnol. 37: 852-857. https://doi.org/10.1038/s41587-019-0209-9
- Shen L, Liu L, Hong-Fang. 2017. Alzheimer's disease histological and behavioral manifestations in transgenic mice correlate with specific gut microbiome state. J. Alzheimer's Dis. 56: 385-390. https://doi.org/10.3233/JAD-160884
- Peng W, Yi P, Yang JJ, Xu PP, Wang Y, Zhang Y, et al. 2018. Association of gut microbiota composition and function with a senescence-accelerated mouse model of Alzheimer's Disease using 16S rRNA gene and metagenomic sequencing analysis. Aging (Albany NY) 10: 4054.
- Zhan G, Yang N, Li S, Huang N, Fang X, Zhang J, et al. 2018. Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice. Aging (Albany NY) 10: 1257.
- Kong Y, B Jiang, X Luo. 2018. Gut microbiota influences Alzheimer's disease pathogenesis by regulating acetate in Drosophila model. Future Microbiol. 13: 1117-1128. https://doi.org/10.2217/fmb-2018-0185
- Barichella M, Severgnini M, Cilia R, Cassani E, Bolliri C, Caroni S, et al. 2019. Unraveling gut microbiota in Parkinson's disease and atypical parkinsonism. Mov. Disord. 34: 396-405. https://doi.org/10.1002/mds.27581
- Ren T, Gao Y, Qio Y, hiang S, Zhang Q, Zhang J, et al. 2020. Gut microbiota altered in mild cognitive impairment compared with normal cognition in sporadic Parkinson's disease. Front. Neurol. 11: 137.
- Vogt NM, Kerby RL, Dill-McFarland KA, harding SJ, Merluzzi AP, Johnson SC, et al. 2017. Gut microbiome alterations in Alzheimer's disease. Sci. Rep. 7: 13537.
- Sun Y, Baptisa LC, Roberts LM, Jumbo-Lucioni P, McMahon LL, Buford TW, et al. 2020. The gut microbiome as a therapeutic target for cognitive impairment. J. Gerontol. 75: 1242-1250. https://doi.org/10.1093/gerona/glz281
- Chen L, Zhang YH, Huang T, Cai YD. 2016. Gene expression profiling gut microbiota in different races of humans. Sci. Rep. 6: 23075.
- Nakayama J, Watanabe K, Jiang J, Matsuda K, Chao SH, Haryono P, et al. 2015. Diversity in gut bacterial community of school-age children in Asia. Sci. Rep. 5: 8397.
- Scheperjans F, Aho V, Pereira PA, Koskinen K, Paulun L, Pekkonen E, et al. 2015. Gut microbiota are related to Parkinson's disease and clinical phenotype. Mov. Disord. 30: 350-358. https://doi.org/10.1002/mds.26069
- Unger MM, Spiegel J, Dillmann KU, Grundmann D, Philippeit H, Burmman H, et al. 2016. Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls. Parkinsonism Relat Disord. 32: 66-72. https://doi.org/10.1016/j.parkreldis.2016.08.019
- Zhu X, Han Y, Du J, Liu R, Jin K, Yi W. 2017. Microbiota-gut-brain axis and the central nervous system. Oncotarget. 8: 53829.
- Bello-Medina PC, Corona-Cervantes K, Torres NGZ, Gonzalez A, Perez-Morales M, Gonzalez-Franco DA, et al. 2022. Chronic-antibiotics induced gut microbiota dysbiosis rescues memory impairment and reduces β-Amyloid Aggregation in a Preclinical Alzheimer's Disease Model. Int. J. Mol. Sci. 23: 8209.
- Romano S, Savva GM, Bedarf JR, Charles IG, Hildebradn F, Narbad A. 2021. Meta-analysis of the Parkinson's disease gut microbiome suggests alterations linked to intestinal inflammation. NPJ Parkinsons Dis. 7: 27.
- Su J, Braat H, Peppelenbosch MP. 2021. Gut microbiota-derived propionate production may explain beneficial effects of intermittent fasting in experimental colitis. J. Crohn's Colitis. 15: 1081-1082. https://doi.org/10.1093/ecco-jcc/jjaa248
- Hou YF, Shan C, Zhuang SY, Zhuang QQ, Ghosh A, Zhu KC, et al. 2021. Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson's disease. Microbiome 9: 34.
- Ou Z, Deng L, Lu Z, Wu F, Liu W, Huang D, Peng Y. 2020. Protective effects of Akkermansia muciniphila on cognitive deficits and amyloid pathology in a mouse model of Alzheimer's disease. Nutr. Diabetes 10: 12.
- Jia W, Rajani C, Kaddurah-Daouk R, Li H. 2020. Expert insights: the potential role of the gut microbiome-bile acid-brain axis in the development and progression of Alzheimer's disease and hepatic encephalopathy. Med. Res. Rev. 40: 1496-1507. https://doi.org/10.1002/med.21653
- Li Z, Zhu H, Zhang L, Qin C. 2018. The intestinal microbiome and Alzheimer's disease: a review. AMEM. 1: 180-188. https://doi.org/10.1002/ame2.12033
- Glenn JM, Madero EN, T. Bott NT. 2019. Dietary protein and amino acid intake: links to the maintenance of cognitive health. Nutrients 11: 1315.
- Angoorani P, Ejtahed HS, Siadat SD, Sharifi F, Larijani B. 2022. Is there any link between cognitive impairment and gut microbiota? A systematic review. Gerontology 68: 1201-1213. https://doi.org/10.1159/000522381