Molecules and Cells

  • 제46권10호
  • /
  • Pages.589-591
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  • 2023
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  • 1016-8478(pISSN)
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  • 0219-1032(eISSN)
한국분자세포생물학회 (Korean Society for Molecular and Cellular Biology)
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Exon Junction Complex Is a Molecular Compass of N6-Methyladenosine Modification

  • Inhong Jung (Department of Biological Sciences, Korea Advanced Institute of Science and Technology) ;
  • Yoon Ki Kim (Department of Biological Sciences, Korea Advanced Institute of Science and Technology)
  • 투고 : 2023.06.21
  • 심사 : 2023.07.09
  • 발행 : 2023.10.31
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초록

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과제정보

This work was supported by a National Research Foundation (NRF) of Korea grant funded by the Korean Government (Ministry of Science, ICT, and Future Planning; NRF-2015R1A3A2033665 and NRF-2018R1A5A1024261).

참고문헌

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  2. Choe, J., Ryu, I., Park, O.H., Park, J., Cho, H., Yoo, J.S., Chi, S.W., Kim, M.K., Song, H.K., and Kim, Y.K. (2014). eIF4AIII enhances translation of nuclear cap-binding complex-bound mRNAs by promoting disruption of secondary structures in 5'UTR. Proc. Natl. Acad. Sci. U. S. A. 111, E4577-E4586. https://doi.org/10.1073/pnas.1409695111
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  5. Li, P., Wang, Y., Sun, Y., Jiang, S., and Li, J. (2022). N (6)-methyladenosine RNA methylation: from regulatory mechanisms to potential clinical applications. Front. Cell Dev. Biol. 10, 1055808.
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  7. Singh, G., Kucukural, A., Cenik, C., Leszyk, J.D., Shaffer, S.A., Weng, Z., and Moore, M.J. (2012). The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. Cell 151, 750-764. https://doi.org/10.1016/j.cell.2012.10.007
  8. Uzonyi, A., Dierks, D., Nir, R., Kwon, O.S., Toth, U., Barbosa, I., Burel, C., Brandis, A., Rossmanith, W., Le Hir, H., et al. (2023). Exclusion of m6A from splice-site proximal regions by the exon junction complex dictates m6A topologies and mRNA stability. Mol. Cell 83, 237-251. https://doi.org/10.1016/j.molcel.2022.12.026
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