Journal of Radiation Protection and Research

  • 제48권3호
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  • Pages.144-152
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  • 2023
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  • 2508-1888(pISSN)
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  • 2466-2461(eISSN)
대한방사선방어학회 (The Korean Association for Radiation Protection)
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Color Texture Analysis as a Tool for Quantitative Evaluation of Radiation-Induced Skin Injuries

  • Sung Young Lee (Gijang Heavy Ion Medical Accelerator, Seoul National University Hospital) ;
  • Jin Ho Kim (Department of Radiation Oncology, Seoul National University Hospital) ;
  • Ji Hyun Chang (Department of Radiation Oncology, Seoul National University Hospital) ;
  • Jong Min Park (Department of Radiation Oncology, Seoul National University Hospital) ;
  • Chang Heon Choi (Department of Radiation Oncology, Seoul National University Hospital) ;
  • Jung-in Kim (Department of Radiation Oncology, Seoul National University Hospital) ;
  • So-Yeon Park (Institute of Radiation Medicine, Seoul National University Medical Research Center)
  • 투고 : 2023.07.10
  • 심사 : 2023.08.02
  • 발행 : 2023.09.30
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초록

Background: Color texture analysis was applied as a tool for quantitative evaluation of radiation-induced skin injuries. Materials and Methods: We prospectively selected 20 breast cancer patients who underwent whole-breast radiotherapy after breast-conserving surgery. Color images of skin surfaces for irradiated breasts were obtained by using a mobile skin analyzer. The first skin measurement was performed before the first fraction of radiotherapy, and the subsequent measurement was conducted approximately 10 days after the completion of the entire series of radiotherapy sessions. For comparison, color images of the skin surface for the unirradiated breasts were measured similarly. For each color image, six co-occurrence matrices (red-green [RG], red-blue [RB], and green-blue [GB] from color channels, red [R], green [G], blue [B] from gray channels) can be generated. Four textural features (contrast, correlation, energy, and homogeneity) were calculated for each co-occurrence matrix. Finally, several statistical analyses were used to investigate the performance of the color textural parameters to objectively evaluate the radiation-induced skin damage. Results and Discussion: For the R channel from the gray channel, the differences in the values between the irradiated and unirradiated skin were larger than those of the G and B channels. In addition, for the RG and RB channels, where R was considered in the color channel, the differences were larger than those in the GB channel. When comparing the relative values between gray and color channels, the 'contrast' values for the RG and RB channels were approximately two times greater than those for the R channel for irradiated skin. In contrast, there were no noticeable differences for unirradiated skin. Conclusion: The utilization of color texture analysis has shown promising results in evaluating the severity of skin damage caused by radiation. All textural parameters of the RG and RB co-occurrence matrices could be potential indicators of the extent of skin damage caused by radiation.

키워드

과제정보

This study was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. RS-2023-00253604).

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