Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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Natural Product Extracts for Depression: Analysis of Patent Status in South Korea

우울증에 대한 천연물 추출물 국내 특허 동향 분석

  • Ga-Young Jung (Department of Korean Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Celine Jang (Department of Korean Medicine, College of Korean Medicine, Daegu Haany University) ;
  • Sang-Ho Kim (Department of Korean Medicine, College of Korean Medicine, Daegu Haany University)
  • 정가영 (대구한의대학교 한의과대학 한의학과) ;
  • 장세린 (대구한의대학교 한의과대학 한의학과) ;
  • 김상호 (대구한의대학교 한의과대학 한의학과)
  • Received : 2023.08.24
  • Accepted : 2023.09.22
  • Published : 2023.09.30
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Abstract

Objectives: To analyze the trend of Korean patents of natural product extracts for depression. This study also aimed to enhance the development and application of natural product extracts for depression in Korean herbal medicine. Methods: We searched the Korea Intellectual Property Rights Information Service and Science ON to collect Korean patent data of natural product extracts for depression. Two authors independently screened and assessed full texts of screened patents for eligibility. Included patents were analyzed both quantitatively and qualitatively. Results: A total of 62 patents from 2002 to December 2021 were included for analysis. The number of patents has constantly increased since 2002. Glycyrrhiza uralensis Fischer, Perilla frutescens Britton var. acuta Kudo, Zizyphus jujuba Miller var. inermis Rehder were frequently used among 62 patents. Alcohol extraction was mostly used, followed by water extraction and ethyl extraction regarding extract methods. Eight patents were herbal medicine used for treating depression in Korean Medicine. Conclusions: Various Korean herbal medicine and minerals were used as natural-products for treating depression. These results provide fundamental data that can be used for inventing new patents using Korean herbal medicine, developing new natural product extracts for depression, and extending the range of application of these products in clinical setting.

Keywords

Acknowledgement

This research was funded by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Wel-fare, Republic of Korea (grant number: HF21C0036).

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