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Effect of Korean Medical Treatment on Patients with Insomnia and Analysis of Correlation among Psychological Scale Changes: A Retrospective Chart Review

불면장애 환자의 한의치료 효과 및 심리척도 변화간 상관성 분석: 후향적 관찰 연구

  • Sang-Il Seo (Haneum Neuropsychiatry Clinic of Korean Medicine) ;
  • Geun-Woo Kim (Department of Neuropsychiatry, College of Korean Medicine, Dongguk University) ;
  • Jong-Ho Yoo (Haneum Neuropsychiatry Clinic of Korean Medicine)
  • 서상일 (한음한방신경정신과한의원) ;
  • 김근우 (동국대학교 한의과대학 한방신경정신과학교실) ;
  • 유종호 (한음한방신경정신과한의원)
  • Received : 2023.08.18
  • Accepted : 2023.09.14
  • Published : 2023.09.30

Abstract

Objectives: To examine effect of Korean medical treatment on patients with insomnia and correlations among changes in psychological scales before and after treatment. Methods: Medical records of 38 patients diagnosed with insomnia based on DSM-V who received Korean medical treatment (herbal-medication, acupuncture, Korean psychotherapy) for at least 8 weeks were retrospectively reviewed. Psychological scales including Insomnia Severity Scale (ISI), Beck Depression Inventory-II (BDI-II), State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and State-Trait Anger Expression Inventory (STAXI) were measured every four weeks and analyzed. Results: After eight weeks of treatment, ISI, BDI-II, BAI, STAI-X-1/2, and STAXI-S/T showed statistically significant decreases. Psychological scale pairs that showed a statistically significant correlation were ISI and BDI-IIㆍSTAI-X-1ㆍSTAI-X-2ㆍTA, BDI-II and BAIㆍSTAI-X-1ㆍSTAI-X-2ㆍAX-I, BAI and STAI-X-1ㆍSTAI-X-2ㆍSAㆍTA, STAI-X-1 and STAI-X-2, SA and TA, and TA and AX-I. In women, the improvement of AX-C was high. The improvement in AX-I score was significant when the disease duration was more than one year. A lower pretreatment BAI value predicted a greater decrease in ISI score after treatment. Conclusions: Korean medical treatment including herbal medicine, acupuncture, and Korean psychotherapy was effective in improving insomnia symptoms and accompanying symptoms such as depression, anxiety, and anger. In the future, more in-depth follow-up research is needed on the mechanisms by which various psychological problems (depression, anxiety, anger, etc) cause and worsen insomnia and the psychological symptoms secondary to insomnia.

Keywords

References

  1. Morin CM, Drake CL, Harvey AG, Krystal AD, Manber R, Riemann D, et al. Insomnia disorder. Nat Rev Dis Primers. 2015;1:15026.
  2. Cho YW, Shin WC, Yun CH, Hong SB, Kim JH, Earley CJ. Epidemiology of insomnia in Korean adults: prevalence and associated factors. J Clin Neurol. 2009;5:20-3. https://doi.org/10.3988/jcn.2009.5.1.20
  3. Benjamin J. Sadock. Kaplan and Sadock's synopsis of psychiatry: behavioral sciences/clinical psychiatry 11th ed. Philadelphia; Lippincott Williams & Wilkins. 2014: 533-63.
  4. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Kwon JS, Kim JJ, Namgkoong K et al., translator. Seoul: Hakjisa; 2016; 391-459.
  5. Kim JD, Son MS. National health insurance statistical yearbook. Seoul: Health Insurance Review and Assessment Service and National Health Insurance Service. 2020.
  6. Winkler A, Auer C, Doering BK, Rief W. Drug treatment of primary insomnia: a meta-analysis of polysomnographic randomized controlled trials. CNS Drugs. 2014;28:799-816. https://doi.org/10.1007/s40263-014-0198-7
  7. Wilt TJ, MacDonald R, Brasure M, Olson CM, Carlyle M, Fuchs E. Pharmacologic treatment of insomnia disorder: an evidence report for a clinical practice guideline by the American college of physicians. Ann Intern Med. 2016; 165:103-12. https://doi.org/10.7326/M15-1781
  8. Kim SJ. Recent Advances in diagnosis and treatment of insomnia disorder. J Korean Neuropsychiatr Assoc. 2020; 59:2-12. https://doi.org/10.4306/jknpa.2020.59.1.2
  9. Morin CM, Vallieres A, Guay B, Ivers H, Savard J, Merette C, Bastien C, Baillargeon L. Cognitive behavioral therapy, singly and combined with medication, for persistent insomnia: a randomized controlled trial. Jama. 2009;301: 2005-15. https://doi.org/10.1001/jama.2009.682
  10. Mitchell MD, Gehrman P, Perlis M, Umscheid CA. Com - parative effectiveness of cognitive behavioral therapy for insomnia: a systematic review. BMC Family Practice. 2012; 13-40.
  11. The korean society of oriental neuropsychiatry. insomnia disorder clinical practice guideline of korean medicine. Seoul:Gunjachulpansa. 2021:3-8.
  12. Lee GE, Mun SJ, Lee SI, Lim JH, We YM, Moon KS et al. Analysis of Quantitative Electroencephalography (QEEG) following acupuncture treatment in patients with insomnia: Z scored absolute power and sLORETA. J of Oriental Neuropsychiatry. 2016;27:169-84.
  13. Park DM, Lee SR, Jung IC. Depression, anxiety, and insomnia patients and its value. J of Oriental Neuropsychiatry. 2012;23:63-76. https://doi.org/10.7231/JON.2012.23.3.063
  14. Jeong JH, Lee JY, Kim JY, Kim SY, Kang WC, Lim JH et al. A pilot study of evaluating the reliability and validity of pattern identification tool for insomnia and analyzing correlation with psychological tests. J of Oriental Neuropsychiatry. 2020;31:1-12.
  15. Kim NH, Choi HM, Lim SW, Oh KS. The relationship between insomnia severity and depression, anxiety and anxiety sensitivity in general population. Sleep Medicine and Psychophysiology. 2006;13:59-66.
  16. Cho YW, Song ML, Morin CM. Validation of a Korean version of the insomnia severity index. J Clin Neurol. 2014; 10:210-5. https://doi.org/10.3988/jcn.2014.10.3.210
  17. Sung HM, Kim JB, Park YN, Bai DS, Lee SH, Ahn HN. A study on the reliability and the validity of Korean version of the Beck Depression Inventory-II(BDI-II). J Korean Soc Biol Ther Psychiatry. 2008;14:201-12.
  18. Yook SP, KIM JS. Comparative study of patient and nonpatient: A clinical study on the Korean version of Beck Anxiety Inventory. The Korean Journal of Clinical Psychology. 1997;16:185-97.
  19. Hahn DW, Lee CH, Chon KK. Korean Adaptation of Spielberger's STAI (K-STAI). Korean Journal of Health Psychology. 1996;1:1-14.
  20. Chon KK, Hahn, DW, Lee, CH. Korean adaptation of the State-Trait Anger Expression Inventory (STAXI-L): the case of college students. Korean Journal of Health Psychology. 1998;3:18-32.
  21. The textbook compilation committee of neuropsychiatry of oriental schools in nation. The Neuropsychiatry of Oriental Medicine. 3rd ed. Seoul:Jipmoondang. 2016:235-48.
  22. American academy of sleep medicine. international classification of sleep disorders. 3rd ed. Darien, IL: American Academy of Sleep Medicine;2014.
  23. Morin CM, Benca R. Chronic insomnia. Lancet. 2012;379: 1129-41. https://doi.org/10.1016/S0140-6736(11)60750-2
  24. Lee SD, Ryu SH, Ha JH, Jeon HJ, Park DH. Analysis of State-Trait Anxiety Inventory for patients diagnosed with insomnia in an outpatient department. Sleep Medicine and Psychophysiology. 2019;26:104-10.
  25. Mai E, Buysse DJ. Insomnia: prevalence, impact, pathogenesis, differential diagnosis, and evaluation. Sleep Med Clin. 2008;3:167-74. https://doi.org/10.1016/j.jsmc.2008.02.001
  26. Taylor DJ, Lichstein KL, Durrence HH, Reidel BW, Bush AJ. Epidemiology of insomnia, depression, and anxiety. Sleep. 2005;28:1457-64. https://doi.org/10.1093/sleep/28.11.1457
  27. Fernandez-Mendoza J, Calhoun SL, Bixler EO, Karataraki M, Liao D, Vela-Bueno A. Sleep misperception and chronic insomnia in the general population: role of objective sleep duration and psychological profiles. Psychosom Med. 2011;73:88-97. https://doi.org/10.1097/PSY.0b013e3181fe365a
  28. Edinger JD, Fins AI, Glenn DM, Sullivan Jr RJ, Bastian LA, Marsh GR. Insomnia and the eye of the beholder: are there clinical markers of objective sleep disturbances among adults with and without insomnia complaints? J Consult Clin Psychol. 2000;68:586.
  29. Sivertsen B, Krokstad S, Mykletun A, Overland S. Insom - nia symptoms and use of health care services and medications: the HUNT-2 study. Behav Sleep Med. 2009;7: 210-22. https://doi.org/10.1080/15402000903190199
  30. Dirksen SR, Epstein DR. Efficacy of an insomnia intervention on fatigue, mood and quality of life in breast cancer survivors. J Adv Nurs. 2008;61:664-75. https://doi.org/10.1111/j.1365-2648.2007.04560.x
  31. Raglan GB, Swanson LM, Arnedt JT. Cognitive behavioral therapy for insomnia in patients with medical and psychiatric comorbidities. Sleep Med Clin. 2019;14:167-75. https://doi.org/10.1016/j.jsmc.2019.01.001
  32. Gebara MA, Siripong N, DiNapoli EA, Maree RD, Germain A, Reynolds CF. Effect of insomnia treatments on depression: a systematic review and meta-analysis. Depress Anxiety. 2018;35:717-31. https://doi.org/10.1002/da.22776
  33. Zhang B, Wing YK. Sex differences in insomnia: a metaanalysis. Sleep. 2006;29:85-93. https://doi.org/10.1093/sleep/29.1.85
  34. Son CW, Lim YC, Lee YS, Lim JH, Kim BK, Ha IH. Analysis of medical services for insomnia in Korea: a retrospective, cross-sectional study using the health insurance review and assessment claims data. Healthcare. 2022;10. https://doi.org/10.3390/healthcare10010007
  35. Partinen M, Eskelinen L, Tuomi K. Complaints of insomnia in different occupations. Scand J Work Environ Health. 1984;10:467-9. https://doi.org/10.5271/sjweh.2297
  36. Kim HC, Kim BK, Min KB, Min JY, Hwang SH, Park SG. Association between job stress and insomnia in Korean workers. J Occup Health. 2011;53:164-74. https://doi.org/10.1539/joh.10-0032-OA
  37. Kucharczyk ER, Morgan K, Hall AP. The occupational im - pact of sleep quality and insomnia symptoms. Sleep Med Rev. 2012;16:547-59.
  38. Yang M, Morin CM, Schaefer K, Wallenstein GV. Interpreting score differences in the Insomnia Severity Index: using health-related outcomes to define the minimally im - portant difference. Curr Med Res Opin. 2009;25:2487-94. https://doi.org/10.1185/03007990903167415
  39. Mai E, Buysse DJ. Insomnia: prevalence, impact, pathogenesis, differential diagnosis, and evaluation. Sleep Med Clin 2008;3:167-74. https://doi.org/10.1016/j.jsmc.2008.02.001
  40. Chon KK, Suh KH, Yi JS, Roh SW, Kim SJ, Lee YM et al. Development of the Korean adaptation of the State-Trait Anger Expression Inventory-2. Kor. J. Psychol.: Health. 2023;28:537-59.
  41. Lee SH. The relationship among interpersonal stress, coping strategies, and anger expression in university students. M.A. dissertation, Dept. Psy. Ewha Womans Univ. Seoul. 2009.
  42. Russell MA, Smith TW, Smyth JM. Anger expression, momentary anger, and symptom severity in patients with chronic disease. Ann Behav Med. 2016;50:259-71. https://doi.org/10.1007/s12160-015-9747-7
  43. Relationship of anxiety disorders, sleep quality, and functional impairment in a community sample. Ramsawh HJ, Stein MB, Belik SL, Jacobi F, Sareen J. J Psychiatric Res. 2009;43:926-33. https://doi.org/10.1016/j.jpsychires.2009.01.009
  44. Kim HK, Kim SH, Jang SI, Park EC. Association between sleep quality and anxiety in Korean adolescents. J Prev Med Public Health. 2022;55:173-81. https://doi.org/10.3961/jpmph.21.498
  45. Leyfer OT, Ruberg JL, Woodruff-Borden J. Examination of the utility of the Beck Anxiety Inventory and its factors as a screener for anxiety disorders. Journal of Anxiety Disorders, 2006;20:444-58. https://doi.org/10.1016/j.janxdis.2005.05.004