Journal of the Health Care and Life Science (보건의료생명과학 논문지)

The Korean Society of Medical Informatics Education (한국의료정보교육협회)
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The relationship between uric acid and anemia in Korean adults with chronic kidney disease

국내 만성신장질환자에서 나타나는 요산과 빈혈과의 관련성

  • Seung Bum Yang (Dep. of Medical Non-commissioned Officer, Wonkwang Health Science University)
  • 양승범 (원광보건대학교 의무부사관과)
  • Received : 2023.04.16
  • Accepted : 2023.05.20
  • Published : 2023.07.31
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Abstract

The present study was conducted to assess the relationship between hyperuricemia and anemia in Korean adults with chronic kidney disease (CKD). Data from 557 adults (age ≥ 20 years) in the Eighth Korean National Health and Nutrition Examination Survey (2019-2021) were analyzed. Several key findings were identified. First, after adjusting for the related variables, the odds ratio (OR) of anemia (hemoglobin [Hb] < 13.0 mg/dL in men or < 12 mg/dL in women), using the normouricemia group (uric acid [UA] < 7.0 mg/dL in men or < 6.0 mg/dL in women) as a reference, was positively significant for the hyperuricemia group (uric acid [UA] ≥ 7.0 mg/dL in men or ≥ 6.0 mg/dL in women) in overall population (odds ratio [OR], 1.719; 95% confidence interval [CI], 1.371-2.942), men (OR, 2.008; 95% CI, 1.013-3.165), and women (OR, 2.246; 95% CI, 1.315-3.835). In conclusions, hyperuricemia was associated with an increase in anemia in both Korean men and women with chronic kidney disease.

본 연구는 만성신장질환이 있는 한국 성인의 고요산혈증과 빈혈과의 관계를 알아보기 위해 제8기 국민건강 영양조사(2019~2021)를 바탕으로 20세 이상의 성인 557명의 자료를 분석했다. 본 연구에서는 몇 가지 주요한 결과가 있었다. 관련 변수를 조정한 후, 정상요산군(남성, 요산[uric acid, UA] < 7.0 mg/dL; 여성, UA < 6.0 mg/dL)에 비하여 고요산혈증군(남성, UA ≥ 7.0 mg/dL; 여성, UA ≥ 6.0 mg/dL)의 빈혈 발생 교차비(odds ratio, OR)는 남성(OR, 2.008; 95% confidence interval [CI], 1.013-3.165)과 여성(OR, 2.246; 95% CI, 1.315 -3.835) 및 만성신장질환 전체(OR, 1.719; 95% CI, 1.371-2.942)에서 유의하게 높았다. 결론적으로 고요산혈증은 만성신장질환을 가진 한국인 남녀 모두에서 빈혈 증가와 관련이 있었다.

Keywords

Acknowledgement

본 논문은 원광보건대학교 연구과제(2023년)로 수행되었음.

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