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Forgetting Is Not the Mere Opposite of Learning

  • Soh-Hyon Jang (Department of Life Sciences, Pohang University of Science and Technology)
  • 투고 : 2023.05.02
  • 심사 : 2023.05.08
  • 발행 : 2023.08.31

초록

키워드

참고문헌

  1. Davis, R.L. and Zhong, Y. (2017). The biology of forgetting-a perspective. Neuron 95, 490-503. https://doi.org/10.1016/j.neuron.2017.05.039
  2. Hardt, O., Nader, K., and Wang, Y.T. (2014). GluA2-dependent AMPA receptor endocytosis and the decay of early and late long-term potentiation: possible mechanisms for forgetting of short- and long-term memories. Philos. Trans. R. Soc. Lond. B Biol. Sci. 369, 20130141.
  3. Kirkpatrick, J., Pascanu, R., Rabinowitz, N., Veness, J., Desjardins, G., Rusu, A.A., Milan, K., Quan, J., Ramalho, T., Grabska-Barwinska, A., et al. (2017). Overcoming catastrophic forgetting in neural networks. Proc. Natl. Acad. Sci. U. S. A. 114, 3521-3526. https://doi.org/10.1073/pnas.1611835114
  4. Marco, A., Meharena, H.S., Dileep, V., Raju, R.M., Davila-Velderrain, J., Zhang, A.L., Adaikkan, C., Young, J.Z., Gao, F., Kellis, M., et al. (2020). Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble. Nat. Neurosci. 23, 1606-1617. https://doi.org/10.1038/s41593-020-00717-0
  5. Ryan, T.J. and Frankland, P.W. (2022). Forgetting as a form of adaptive engram cell plasticity. Nat. Rev. Neurosci. 23, 173-186. https://doi.org/10.1038/s41583-021-00548-3
  6. Ryan, T.J., Roy, D.S., Pignatelli, M., Arons, A., and Tonegawa, S. (2015). Memory. Engram cells retain memory under retrograde amnesia. Science 348, 1007-1013. https://doi.org/10.1126/science.aaa5542
  7. Ten Oever, S., Sack, A.T., Oehrn, C.R., and Axmacher, N. (2021). An engram of intentionally forgotten information. Nat. Commun. 12, 6443.
  8. Tonegawa, S., Liu, X., Ramirez, S., and Redondo, R. (2015). Memory engram cells have come of age. Neuron 87, 918-931. https://doi.org/10.1016/j.neuron.2015.08.002
  9. Tonegawa, S., Morrissey, M.D., and Kitamura, T. (2018). The role of engram cells in the systems consolidation of memory. Nat. Rev. Neurosci. 19, 485-498. https://doi.org/10.1038/s41583-018-0031-2