Clinical and Experimental Vaccine Research

The Korean Vaccine Society (대한백신학회)
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Psoriasis flares after COVID-19 vaccination: adherence to biologic therapy reduces psoriasis exacerbations: a case-control study

  • Martina Burlando (Section of Dermatology, Department of Health Sciences (DISSAL), San Martino Polyclinic Hospital IRCCS, University of Genoa) ;
  • Astrid Herzum (Section of Dermatology, Department of Health Sciences (DISSAL), San Martino Polyclinic Hospital IRCCS, University of Genoa) ;
  • Emanuele Cozzani (Section of Dermatology, Department of Health Sciences (DISSAL), San Martino Polyclinic Hospital IRCCS, University of Genoa) ;
  • Aurora Parodi (Section of Dermatology, Department of Health Sciences (DISSAL), San Martino Polyclinic Hospital IRCCS, University of Genoa)
  • Received : 2022.05.02
  • Accepted : 2022.12.22
  • Published : 2023.01.31
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Abstract

This study aimed to evaluate if patients under biologics have a lower risk of psoriasis flares after coronavirus disease 2019 (COVID-19) vaccination than other psoriatic patients. Of 322 recently vaccinated patients admitted for psoriasis at the Dermatological Psoriasis Unit during January and February 2022, 316 (98%) had no psoriasis flares after COVID-19 vaccination (79% under biologic treatment, 21% not biologically treated) and 6 (2%) presented psoriasis flares after COVID-19 vaccination (33.3% under biologic treatment, 66.6% not biologically treated). Overall, psoriasis patients under biologic treatment, developed fewer psoriasis flares after COVID-19 vaccination (33.3%), than patients not under biologic treatment (66.6%) (p=0.0207; Fisher's exact test).

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References

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