Journal of Pharmacopuncture (대한약침학회지)

KOREAN PHARMACOPUNCTURE INSTITUTE (대한약침학회)
권호 표지
DOI QR코드

DOI QR Code

External Treatment of Pyritum for Musculoskeletal Trauma: a protocol for systematic review

  • Ji Hye Hwang (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Gachon University) ;
  • Su Hyun Choi (College of Korean Medicine, Gachon University)
  • Received : 2023.04.01
  • Accepted : 2023.05.19
  • Published : 2023.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: Musculoskeletal trauma is a common type of injury that can result from damage to the muscular or skeletal system and has been recognized as a leading cause of death and disability worldwide. This study aims to analyze the efficacy of Pyritum external treatment for musculoskeletal trauma. Methods: Randomized controlled trials evaluating the external treatment effect of Pyritum on various types of musculoskeletal traumatic injuries will be considered and identified in the searches of eight databases from their inception to Feb 2023. There will be no restrictions with respect to the publication status, language, or country. The experimental intervention group will be treated with external application of Pyritum alone or in combination with other therapies, and the comparator intervention group will include all types of control interventions. The primary outcome will be measured as treatment efficacy rate, and secondary outcomes will include pain reduction, pain disappearance time, swelling, joint function, and recovery period. Assessment of the methodological quality of this study will be concluded using the risk of bias assessment recommended by the Cochrane Collaboration. If there are sufficient numbers of studies per group in terms of specific rating scales to compare the treatment effects of Pyrium alone and combined external treatment groups, we will consider subgroup analysis. Results: This systematic review will be conducted in compliance with the PRISMA-P statement. Conclusion: We will conduct an extensive search on the proposed topic within the available literature and provide systematic evidence for the efficacy and safety of external application of Pyritum for all types of musculoskeletal trauma. The evidence generated will help design interventions for the external use of Pyritum for this patient group.

Keywords

Acknowledgement

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. NRF-2022R1A2C1013518).

References

  1. Joshipura M, Mock C, Goosen J, Peden M. Essential trauma care: strengthening trauma systems round the world. Injury. 2004;35(9):841-5. https://doi.org/10.1016/j.injury.2003.08.005
  2. Mock C, Kobusingye O, Joshipura M, Nguyen S, Arreola-Risa C. Strengthening trauma and critical care globally. Curr Opin Crit Care. 2005;11(6):568-75. https://doi.org/10.1097/01.ccx.0000186373.49320.65
  3. Vukasinovic Z, Spasovski D, Zivkovic Z. Musculoskeletal trauma services in Serbia. Clin Orthop Relat Res. 2008;466(10):2337-42. https://doi.org/10.1007/s11999-008-0364-7
  4. Lee JE, Lee CH, Lee EJ, Lee JM, Oh MS. Systematic review of bee venom therapy for traumatic injury. J Korean Med Rehabil. 2016;26(3):67-77. https://doi.org/10.18325/jkmr.2016.26.3.67
  5. El-Tallawy SN, Nalamasu R, Salem GI, LeQuang JAK, Pergolizzi JV, Christo PJ. Management of musculoskeletal pain: an update with emphasis on chronic musculoskeletal pain. Pain Ther. 2021;10(1):181-209. https://doi.org/10.1007/s40122-021-00235-2
  6. Smith E, Hoy DG, Cross M, Vos T, Naghavi M, Buchbinder R, et al. The global burden of other musculoskeletal disorders: estimates from the Global Burden of Disease 2010 study. Ann Rheum Dis. 2014;73(8):1462-9. https://doi.org/10.1136/annrheumdis-2013-204680
  7. Bong SM, Jo HR, Jang WS, Choi SK, Sung WS, Jung CY, et al. Efficacy and safety of blood stasis based herbal medicine for patients with traffic accident: a prospective observational study. J Acupunct Res. 2020;37(3):151-60. https://doi.org/10.13045/jar.2020.00038
  8. Liu X, Wang Y, Ye Q, Sun Y, Yang J, Dai Y, et al. External treatment of traditional Chinese medicine for constipation after thoracolumbar compression fractures: a protocol for systematic review and meta-analysis. Medicine (Baltimore). 2021;100(35):e27110.
  9. Ha Y, Shin G. A case report on multiple rib fracture improved with Daewhangchija-paste adhesive treatment and herb-medicine treatment. J Korean Med. 2020;41(3):151-61. https://doi.org/10.13048/jkm.20031
  10. Yang GY, Lee EK, Choi EH, Jeon JH, Lee BR, Kim YI. A literature review on the adhesive herbal treatment on sprain. J Acupunct Res. 2009;26(1):23-8.
  11. Kim E, Choi J, Min SY. Combined effect of external treatment of herbal medicine and tuina in congenital muscular torticollis: systematic review and meta-analysis. Medicine (Baltimore). 2022;101(48):e32086.
  12. Cavero RY, Calvo MI. Medicinal plants used for musculoskeletal disorders in Navarra and their pharmacological validation. J Ethnopharmacol. 2015;168:255-9. https://doi.org/10.1016/j.jep.2015.03.078
  13. Sul JU, Kim SJ, An HR, Chung IM, Shin MS, Jang HJ, et al. A philological study on the pyrite. Korean J Orient Med Prescr. 2006;14(1):82-104.
  14. Choi SH, Nam EY, Hwang JH. Therapeutic efficacy of Chinese patent medicine containing pyrite for fractures: a protocol for systematic review and meta-analysis. Medicine (Baltimore). 2022;101(49):e32267.
  15. Hwang J, Ahn J, Kim J, Ahn S, Kim K, Cho H, et al. Effects of administration of pyritum on activation of osteoblast cells in human body & on tibia bone fracture in mice. J Korean Acupunct Moxibustion Med Soc. 2009;26(2):159-70.
  16. Sung HK, Kim JH, Min SY. A case report of delayed healing in femoral shaft fractured child. J Pediatr Korean Med. 2011;25(1):63-71. https://doi.org/10.7778/jpkm.2011.25.1.063
  17. Herbology Editorial Committee of Korean Medicine Schools. [Herbology]. Seoul: Yeonglimsa; 2004. p. 619-21. Korean.
  18. Wang LL, Zuo RT, Chen SQ. Analysis on therapeutic effects and adverse reactions of Chinese patent drug containing mineral medicine. Chin Med Pharm. 2017;19:50-4.
  19. Hu ZC. A network meta-analysis of the effect of five oral Chinese herbal prescriptions on limb fractures [master's thesis]. [Hubei]: Hubei University of Traditional Chinese Medicine; 2020.
  20. Wang JQ. Treatment of 93 cases of acute soft tissue injury by external application of Dita Zhitong powder. Shaanxi J Tradit Chin Med. 2007;8:1018-9.
  21. Xie YY. Clinical observation on the treatment of tumor and pain after fracture with external application of Shangke Jiegu tablets. Acta Med Sin. 1998;1:55.
  22. Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, et al.; PRISMA-P Group. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015;4(1):1.