Hip & pelvis

The Korean Hip Society (대한고관절학회)
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Efficacy of Pericapsular Nerve Group Block for Pain Reduction and Opioid Consumption after Total Hip Arthroplasty: A Meta-Analysis of Randomized Controlled Trials

  • Eunsoo Kim (Department of Anesthesia and Pain Medicine, Bio-Medical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine) ;
  • Won Chul Shin (Department of Orthopaedic Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine) ;
  • Sang Min Lee (Department of Orthopaedic Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine) ;
  • Min Jun Choi (Department of Orthopaedic Surgery, Bio-Medical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine) ;
  • Nam Hoon Moon (Department of Orthopaedic Surgery, Bio-Medical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine)
  • Received : 2022.05.26
  • Accepted : 2022.11.17
  • Published : 2023.06.30
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Abstract

The aim of this study was to conduct a meta-analysis of randomized controlled trials (RCTs) for comparison of the effectiveness of pericapsular nerve group (PENG) block with that of other analgesic techniques for reduction of postoperative pain and consumption of opioids after total hip arthroplasty (THA). A search of records in the PubMed, Embase, and Cochrane Library, and ClinicalTrials.gov databases was conducted in order to identify studies comparing the effect of the PENG block with that of other analgesics on reduction of postoperative pain and consumption of opioids after THA. Determination of eligibility was based on the PICOS (participants, intervention, comparator, outcomes, and study design) criteria as follows: (1) Participants: patients who underwent THA. (2) Intervention: patients who received a PENG block for management of postoperative pain. (3) Comparator: patients who received other analgesics. (4) Outcomes: numerical rating scale (NRS) score and opioid consumption during different periods. (5) Study design: clinical RCTs. Five RCTs were finally included in the current meta-analysis. Significantly lower postoperative opioid consumption at 24 hours after THA was observed in the group of patients who received the PENG block compared with the control group (standard mean difference=-0.36, 95% confidence interval -0.64 to -0.08). However, no significant reduction in NRS score at 12, 24, and 48 hours after surgery and opioid consumption at 48 hours after THA was observed. The PENG block showed better results for opioid consumption at 24 hours after THA compared with other analgesics.

Keywords

Acknowledgement

This work was supported by a clinical research grant from Pusan National University Hospital in 2022.

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