과제정보
This paper was supported by Konkuk University Premier Research Fund in 2019.
참고문헌
- Mukherjee B, Morgenbesser SD, DePinho RA. Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants. Genes Dev 1992;6:1480-1492 https://doi.org/10.1101/gad.6.8.1480
- Walker W, Zhou ZQ, Ota S, Wynshaw-Boris A, Hurlin PJ. Mnt-Max to Myc-Max complex switching regulates cell cycle entry. J Cell Biol 2005;169:405-413 https://doi.org/10.1083/jcb.200411013
- Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872 https://doi.org/10.1016/j.cell.2007.11.019
- Davis AC, Wims M, Spotts GD, Hann SR, Bradley A. A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice. Genes Dev 1993;7:671-682 https://doi.org/10.1101/gad.7.4.671
- Stanton BR, Perkins AS, Tessarollo L, Sassoon DA, Parada LF. Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. Genes Dev 1992;6:2235-2247 https://doi.org/10.1101/gad.6.12a.2235
- Moens CB, Auerbach AB, Conlon RA, Joyner AL, Rossant J. A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung. Genes Dev 1992;6:691-704 https://doi.org/10.1101/gad.6.5.691
- Charron J, Malynn BA, Fisher P, Stewart V, Jeannotte L, Goff SP, Robertson EJ, Alt FW. Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene. Genes Dev 1992;6:2248-2257 https://doi.org/10.1101/gad.6.12a.2248
- Hatton KS, Mahon K, Chin L, Chiu FC, Lee HW, Peng D, Morgenbesser SD, Horner J, DePinho RA. Expression and activity of L-Myc in normal mouse development. Mol Cell Biol 1996;16:1794-1804 https://doi.org/10.1128/MCB.16.4.1794
- Hurlin PJ. Control of vertebrate development by MYC. Cold Spring Harb Perspect Med 2013;3:a014332
- Alitalo K, Bishop JM, Smith DH, Chen EY, Colby WW, Levinson AD. Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29. Proc Natl Acad Sci USA 1983;80:100-104 https://doi.org/10.1073/pnas.80.1.100
- Dalla-Favera R, Bregni M, Erikson J, Patterson D, Gallo RC, Croce CM. Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc Natl Acad Sci USA 1982;79:7824-7827 https://doi.org/10.1073/pnas.79.24.7824
- Sheiness DK, Hughes SH, Varmus HE, Stubblefield E, Bishop JM. The vertebrate homolog of the putative transforming gene of avian myelocytomatosis virus: characteristics of the DNA locus and its RNA transcript. Virology 1980;105:415-424 https://doi.org/10.1016/0042-6822(80)90042-2
- Nau MM, Brooks BJ, Battey J, Sausville E, Gazdar AF, Kirsch IR, McBride OW, Bertness V, Hollis GF, Minna JD. L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer. Nature 1985;318:69-73 https://doi.org/10.1038/318069a0
- Schwab M, Varmus HE, Bishop JM, Grzeschik KH, Naylor SL, Sakaguchi AY, Brodeur G, Trent J. Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc. Nature 1984;308:288-291 https://doi.org/10.1038/308288a0
- Seeger RC, Brodeur GM, Sather H, Dalton A, Siegel SE, Wong KY, Hammond D. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 1985;313:1111-1116 https://doi.org/10.1056/NEJM198510313131802
- Nilsson JA, Cleveland JL. Myc pathways provoking cell suicide and cancer. Oncogene 2003;22:9007-9021 https://doi.org/10.1038/sj.onc.1207261
- Alarcon-Vargas D, Tansey WP, Ronai Z. Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc. Oncogene 2002;21:4384-4391 https://doi.org/10.1038/sj.onc.1205543
- Channavajhala P, Seldin DC. Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis. Oncogene 2002;21:5280-5288 https://doi.org/10.1038/sj.onc.1205640
- Noguchi K, Kokubu A, Kitanaka C, Ichijo H, Kuchino Y. ASK1-signaling promotes c-Myc protein stability during apoptosis. Biochem Biophys Res Commun 2001;281:1313-1320 https://doi.org/10.1006/bbrc.2001.4498
- Popescu NC, Zimonjic DB. Chromosome-mediated alterations of the MYC gene in human cancer. J Cell Mol Med 2002;6:151-159 https://doi.org/10.1111/j.1582-4934.2002.tb00183.x
- Kumari A, Folk WP, Sakamuro D. The dual roles of MYC in genomic instability and cancer chemoresistance. Genes (Basel) 2017;8:158
- Tansey WP. Mammalian MYC proteins and cancer. New J Sci 2014;2014:757534
- Rochlitz CF, Herrmann R, de Kant E. Overexpression and amplification of c-myc during progression of human colorectal cancer. Oncology 1996;53:448-454 https://doi.org/10.1159/000227619
- Xu J, Chen Y, Olopade OI. MYC and breast cancer. Genes Cancer 2010;1:629-640 https://doi.org/10.1177/1947601910378691
- Uribesalgo I, Benitah SA, Di Croce L. From oncogene to tumor suppressor: the dual role of Myc in leukemia. Cell Cycle 2012;11:1757-1764 https://doi.org/10.4161/cc.19883
- Ahmadi SE, Rahimi S, Zarandi B, Chegeni R, Safa M. MYC: a multipurpose oncogene with prognostic and therapeutic implications in blood malignancies. J Hematol Oncol 2021;14:121
- Li Y, Casey SC, Felsher DW. Inactivation of MYC reverses tumorigenesis. J Intern Med 2014;276:52-60 https://doi.org/10.1111/joim.12237
- Kohl NE, Kanda N, Schreck RR, Bruns G, Latt SA, Gilbert F, Alt FW. Transposition and amplification of oncogene-related sequences in human neuroblastomas. Cell 1983;35(2 Pt 1):359-367 https://doi.org/10.1016/0092-8674(83)90169-1
- Stoneley M, Chappell SA, Jopling CL, Dickens M, MacFarlane M, Willis AE. c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis. Mol Cell Biol 2000;20:1162-1169 https://doi.org/10.1128/MCB.20.4.1162-1169.2000
- Hui AB, Lo KW, Yin XL, Poon WS, Ng HK. Detection of multiple gene amplifications in glioblastoma multiforme using array-based comparative genomic hybridization. Lab Invest 2001;81:717-723 https://doi.org/10.1038/labinvest.3780280
- Wong AJ, Ruppert JM, Eggleston J, Hamilton SR, Baylin SB, Vogelstein B. Gene amplification of c-myc and N-myc in small cell carcinoma of the lung. Science 1986;233:461-464 https://doi.org/10.1126/science.3014659
- Kawashima K, Shikama H, Imoto K, Izawa M, Naruke T, Okabayashi K, Nishimura S. Close correlation between restriction fragment length polymorphism of the L-MYC gene and metastasis of human lung cancer to the lymph nodes and other organs. Proc Natl Acad Sci U S A 1988;85:2353-2356 https://doi.org/10.1073/pnas.85.7.2353
- Mosquera JM, Beltran H, Park K, MacDonald TY, Robinson BD, Tagawa ST, Perner S, Bismar TA, Erbersdobler A, Dhir R, Nelson JB, Nanus DM, Rubin MA. Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer. Neoplasia 2013;15:1-10 https://doi.org/10.1593/neo.121550
- Mizukami Y, Nonomura A, Takizawa T, Noguchi M, Michigishi T, Nakamura S, Ishizaki T. N-myc protein expression in human breast carcinoma: prognostic implications. Anticancer Res 1995;15:2899-2905
- Ahmadiyeh N, Pomerantz MM, Grisanzio C, Herman P, Jia L, Almendro V, He HH, Brown M, Liu XS, Davis M, Caswell JL, Beckwith CA, Hills A, Macconaill L, Coetzee GA, Regan MM, Freedman ML. 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC. Proc Natl Acad Sci USA 2010;107:9742-9746 https://doi.org/10.1073/pnas.0910668107
- Koh CM, Bieberich CJ, Dang CV, Nelson WG, Yegnasubramanian S, De Marzo AM. MYC and prostate cancer. Genes Cancer 2010;1:617-628 https://doi.org/10.1177/1947601910379132
- Chen CR, Kang Y, Massague J. Defective repression of c-myc in breast cancer cells: a loss at the core of the transforming growth factor beta growth arrest program. Proc Natl Acad Sci USA 2001;98:992-999 https://doi.org/10.1073/pnas.98.3.992
- Nutt CL, Mani DR, Betensky RA, Tamayo P, Cairncross JG, Ladd C, Pohl U, Hartmann C, McLaughlin ME, Batchelor TT, Black PM, von Deimling A, Pomeroy SL, Golub TR, Louis DN. Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res 2003;63:1602-1607
- Nau MM, Brooks BJ Jr, Carney DN, Gazdar AF, Battey JF, Sausville EA, Minna JD. Human small-cell lung cancers show amplification and expression of the N-myc gene. Proc Natl Acad Sci USA 1986;83:1092-1096 https://doi.org/10.1073/pnas.83.4.1092
- Kawagoe H, Kandilci A, Kranenburg TA, Grosveld GC. Overexpression of N-Myc rapidly causes acute myeloid leukemia in mice. Cancer Res 2007;67:10677-10685 https://doi.org/10.1158/0008-5472.CAN-07-1118
- Wu R, Lin L, Beer DG, Ellenson LH, Lamb BJ, Rouillard JM, Kuick R, Hanash S, Schwartz DR, Fearon ER, Cho KR. Amplification and overexpression of the L-MYC proto-oncogene in ovarian carcinomas. Am J Pathol 2003;162:1603-1610 https://doi.org/10.1016/S0002-9440(10)64294-0
- Xie S, Shen C, Tan M, Li M, Song X, Wang C. Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer. Oncotarget 2017;8:27216-27239 https://doi.org/10.18632/oncotarget.16111
- Cui X, Jing X, Yi Q, Long C, Tan B, Li X, Chen X, Huang Y, Xiang Z, Tian J, Zhu J. Systematic analysis of gene expression alterations and clinical outcomes of STAT3 in cancer. Oncotarget 2017;9:3198-3213 https://doi.org/10.18632/oncotarget.23226
- Matthews L, Gopinath G, Gillespie M, Caudy M, Croft D, de Bono B, Garapati P, Hemish J, Hermjakob H, Jassal B, Kanapin A, Lewis S, Mahajan S, May B, Schmidt E, Vastrik I, Wu G, Birney E, Stein L, D'Eustachio P. Reactome knowledgebase of human biological pathways and processes. Nucleic Acids Res 2009;37(Suppl 1):D619-D622 https://doi.org/10.1093/nar/gkn863
- Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-331 https://doi.org/10.1016/S0092-8674(00)81871-1
- Xu AG, Li SG, Liu JH, Gan AH. Function of apoptosis and expression of the proteins Bcl-2, p53 and C-myc in the development of gastric cancer. World J Gastroenterol 2001;7:403-406 https://doi.org/10.3748/wjg.v7.i3.403
- Weston A, Caporaso NE, Perrin LS, Sugimura H, Tamai S, Krontiris TG, Trump BF, Hoover RN, Harris CC. Relationship of H-ras-1, L-myc, and p53 polymorphisms with lung cancer risk and prognosis. Environ Health Perspect 1992;98:61-67 https://doi.org/10.1289/ehp.929861
- Chen J, Li S, Yang Z, Lu G, Hu H. Correlation between NDRG1 and PTEN expression in endometrial carcinoma. Cancer Sci 2008;99:706-710 https://doi.org/10.1111/j.1349-7006.2008.00749.x
- Liu H, Radisky DC, Yang D, Xu R, Radisky ES, Bissell MJ, Bishop JM. MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits. Nat Cell Biol 2012;14:567-574 https://doi.org/10.1038/ncb2491
- Ma X, Huang J, Tian Y, Chen Y, Yang Y, Zhang X, Zhang F, Xue L. Myc suppresses tumor invasion and cell migration by inhibiting JNK signaling. Oncogene 2017;36:3159-3167 https://doi.org/10.1038/onc.2016.463