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Two Cases of Adult Atopic Dermatitis Improved by Administration of Osuyu-tang

오수유탕(吳茱萸湯) 투여로 호전된 성인형 아토피 피부염 치험 2례

  • Ju-Hyun Lee (Department of Korean Medicine Ophthalmology, Otolaryngology and Dermatology, Wonkwang University Korean Medicine Hospital) ;
  • Sung-Gu Park (Midas Korean Medicine Clinic) ;
  • Eun-Heui Jo (Department of Acupuncture and Moxibustion, Wonkwang University Korean Medicine Hospital) ;
  • Min-Cheol Park (Department of Korean Medicine Ophthalmology, Otolaryngology and Dermatology, Wonkwang University Korean Medicine Hospital)
  • 이주현 (원광대학교 한의과대학 한방안이비인후피부과학교실) ;
  • 박승구 (미다스 한의원) ;
  • 조은희 (원광대학교 한의과대학 침구의학교실) ;
  • 박민철 (원광대학교 한의과대학 한방안이비인후피부과학교실)
  • Received : 2022.07.29
  • Accepted : 2023.02.14
  • Published : 2023.03.01

Abstract

Objectives: This study is to report two cases of adult atopic dermatitis improved by Osuyu-tang. Methods: Osuyu-tang was prescribed to two adult atopic dermatitis patients. The patients took Osuyu-tang 3 times a day for 45 days and 50 days, respectively. Results: In case 1 who complained of redness, erythema, edema, exudation, dryness, erosion, lichenification, scaly, and pruritus, skin symptoms improved from 15 to 2, and pruritus also improved from NRS 8 to 2. In case 2 who complained of redness-centered skin symptoms, skin symptoms improved from 15 to 1, and pruritus also improved from NRS 9 to 1. Conclusions: When Osuyu-tang was prescribed to two patients with adult atopic dermatitis, significant improvement was observed. It is thought that Osyyu-tang can be used as the treatment of other similar diseases in the future.

Keywords

Acknowledgement

본 논문은 2023년도 원광대학교 교내 연구비 지원에 의해서 수행됨.

References

  1. Eichenfield, L.F., Tom, W.L., Chamlin, S.L., Feldman, S.R., Hanifin, J.M., Simpson, E.L., et al. (2014). Guidelines of care for the management of atopic dermatitis: Section 1. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol, 70(2), 338-51. https://doi.org/10.1016/j.jaad.2013.10.010
  2. Hanifin, J.M., Rajka, G. Diagnostic features of atopic dermatitis. (1980). Acta Derm Venereol, 92, 44-7. https://doi.org/10.2340/00015555924447
  3. Rho, E.J. (2018). Gobangyuchwi. Seoul: Barun Herbal Medicine. 771-8.
  4. Carroll, C.L., Balkrishnan, R., Feldman, S.R., Fieischer, A.B., Manuel, J.C. (2005). The burden of atopic dermatitis: Impact on the patient, family, and society. Pediatr Dermatol, 22(3), 192-9. https://doi.org/10.1111/j.1525-1470.2005.22303.x
  5. Ellis, C.N., Mancini, A.J., Paller, A.S., Simpson, E.L., Eichenfield, L.F. (2012). Understanding and managing atopic dermatitis in adult patients. Semin Cutan Med Surg, 31(3), S18-22. https://doi.org/10.1016/j.sder.2012.07.006
  6. Wollenberg, A., Barbarot, S., Bieber, T., Christen-Zaech, S., Deleuran, M., Fink-Wagner, A., et al. (2018). Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I. J Eur Acad Dermatol Venereol, 32(5), 657-782. https://doi.org/10.1111/jdv.14891
  7. Wollenberg, A., Barbarot, S., Bieber, T., Christen-Zaech, S., Deleuran, M., Fink-Wagner, A., et al. (2018). Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part II. J Eur Acad Dermatol Venereol, 32(6), 850-78. https://doi.org/ 10.1111/jdv.14888
  8. Abraham, A., Roga, G. (2014). Topical steroid-damaged skin. Indian J Dermatol, 59(5), 456-9. https://doi.org/10.4103/0019-5154.139872
  9. Rho, E.J. (2018). Gobangyuchwi. Seoul: Barun Herbal Medicine. 771-8.
  10. European Task Force on Atopic Dermatitis. (1993). Severity scoring of atopic dermatitis: the SCORAD index. Dermatology, 186, 23-31. https://doi.org/10.1159/000247298
  11. College of Korean Medicine Dermatology & Surgery Textbook Compilation Committee. (2007). Text of Traditional Korean Dermatology & Surgery. Pusan: Sunwoo. 355-61.
  12. Son, J.S., Choi, I.H. (2001). A case of atopic dermatitis. J Korean Oriental Med, 22(4), 151-7.
  13. Lim, W.K., Sun, Y.J., Ock, M.G., Kim, C.H., Back, S.H. (2004). A clinical case of severe atopic dermatitis. J Korean Med Ophthalmol Otolaryngol Dermatol, 17(3), 114-9.
  14. Korea Centers for Disease Control and Prevention. Atopic dermatitis doctor diagnosis experience rate. Korea Centers for Disease Control and Prevention [serial online] 2020 [Cited 2022 August 23]. Available from: URL:https://index.go.kr/potal/main/EachDtlPageDetail.do?idx_cd=1438
  15. Ju, Y.S. (2013). Jeungbo Ungok Herbology. Wanju: Wooseok. 783-8.
  16. Ryu, M.J. (2014). Functional activities of Evodia officinalis extract as cosmetic materials. Kor J Aesthet Cosmetol, 12(6), 797-804.
  17. Jeon, S.A., Noh, H.M., Jo, E.H., Park, M.C. (2017). Antibiotic, antioxidant and whitening effects of Jwa Kum-Whan and Soo Ryeon-Whan. J Korean Med Ophthalmol Otolaryngol Dermatol, 30(2), 100-11. https://doi.org/10.6114/JKOOD.2017.30.2.100
  18. Lee, S.J., Seo, H.A., Lee, S.I. (2016). A case report of psoriasis treated by Osuyu-tang based on Shanghanlun. Herb Formula Sci, 24(1), 53-61. https://doi.org/10.14374/HFS.2016.24.1.53
  19. Lim, E.K., Jeong, J.W. (2020). A case of nummular eczema treated by Osuyu-tang based on Shanghanlun provisions. J of KMediACS, 12(1), 147-57. https://doi.org/10.22891/KMEDIA.2020.12.1.147
  20. Yun, H.J., Heo, S.K., Lee, Y.T., Park, W.H., Park, S.D. (2008). Anti-inflammatory effect of Evodia Officinalis DODE in mouse macrophage and human vascular endotherial cells. Kor J Herbol, 23(1), 29-38.
  21. Lee, Y.S., Lee, G.H., Park, J.H., Kwon, Y.K., Shin, S.W. (2007). Water extracted Evodiae Fructus possesses immunomodulatory activities on cyclophosphamide induced immunesuppression. J Physiol & Pathol Korean Med, 21(1), 1450-5.