The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
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A Systematic Review and Meta-Analysis on the Effect of Guibi-tang for Postpartum Depression

산후우울증에서 귀비탕(歸脾湯)의 임상효과에 대한 체계적 문헌 고찰 및 메타분석

  • Eun-Sol Kang (Dept. of Korean Obstetrics & Gynecology, Jaseng Hospital of Korean Medicine) ;
  • Young-Tae Ahn (Dept. of Korean Obstetrics & Gynecology, Jaseng Hospital of Korean Medicine) ;
  • Hyo-Jeong Kim (Dept. of Korean Obstetrics & Gynecology, Jaseng Hospital of Korean Medicine) ;
  • Ji-Soo Hyun (Dept. of Korean Obstetrics & Gynecology, Jaseng Hospital of Korean Medicine) ;
  • Jin-Young Kang (Dept. of Korean Neuropsychiatry, Jaseng Hospital of Korean Medicine) ;
  • Yoon-Jae Lee (Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation)
  • 강은솔 (자생한방병원 한방부인과) ;
  • 안영태 (자생한방병원 한방부인과) ;
  • 김효정 (자생한방병원 한방부인과) ;
  • 현지수 (자생한방병원 한방부인과) ;
  • 강진영 (자생한방병원 한방신경정신과) ;
  • 이윤재 (자생의료재단 척추관절연구소)
  • Received : 2023.04.13
  • Accepted : 2023.05.26
  • Published : 2023.05.26
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Abstract

Objectives: The purpose of this study is to analyze the effectiveness of Guibi-tang that are used for postpartum depression. Methods: We searched on five databases [Korean studies Information Service (KISS), Oriental medicine advanced searching integrated system (OASIS), The Cochrane Library, PubMed, and China national knowledge infrastructure (CNKI)] with keywords for Postpartum depression (English, Korean, and Chinese) and evaluated the risk of bias. Meta-analysis was performed on the selected studies. Results: 8 potentially relevant articles were retrieved for further evaluation. There was evidence that Guibi-tang compared with Western medicine was significantly higher rate in total effect rate (RR 1.20, 95% CI 1.04, 1.39, p=0.01). Also, the combined therapeutic effects of Guibi-tang and Psychological intervention compared with Psychological intervention were statistically significant in total effect rate (RR 1.14, 95% CI 1.05, 1.24, p=0.002). And they showed improvement on scores of HAMD (Hamilton depression scale, HAMD) and SF-36 (36-Item short form health survey, SF-36). Conclusion: Guibi-tang appears to be more effective compared to Western medicine in the treatment of postpartum depression. The combination Guibi-tang and Psychological intervention was more effective than psychological intervention alone treated for postpartum depression. However, since unclear risk of bias, the result of this study should be considered carefully. Further clinical trials should be carried out in order to academical clinical progress regarding treatment of Postpartum Depression.

Keywords

References

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