Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • 제49권2호
  • /
  • Pages.96-99
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  • 2023
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  • 2234-7550(pISSN)
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  • 2234-5930(eISSN)
대한구강악안면외과학회 (The Korean Association of Oral and Maxillofacial Surgeons)
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Oral spindle cell/sclerosing rhabdomyosarcoma on mandible with anaplastic lymphoma kinase expression mimicking inflammatory myofibroblastic tumor

  • Joo Young Lee (Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook Universitiy) ;
  • Wonae Lee (Department of Pathology, College of Medicine, Dankook University) ;
  • Moon-Young Kim (Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook Universitiy)
  • 투고 : 2022.01.25
  • 심사 : 2022.03.02
  • 발행 : 2023.04.30
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초록

Oral spindle cell/sclerosing rhabdomyosarcoma (SCRMS) with anaplastic lymphoma kinase (ALK) expression is extremely rare, and its diagnosis is very challenging in the absence of clinical or pathological indicators. This case presented with gingival swelling and alveolar bone resorption and was suspected clinically to be periodontitis. A biopsy was performed and, due to immunoreactivity with ALK, the patient was misdiagnosed with inflammatory myofibroblastic tumor. However, based on the combined histological and immunohistochemical features, a revised diagnosis of SCRMS with ALK expression was finally concluded. We believe that this report makes a significant contribution to the precise diagnosis of this rare disease for proper treatment.

키워드

과제정보

The authors would like to thank Dr. Jerad M. Gardner, a dermatopathologist & section head of bone/soft tissue pathology at Geisinger Medical Center, Danville, Pennsylvania, USA, for his valuable comments on this case.

참고문헌

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