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Rare Manifestation of the Cutaneous and Cervical Lymph Node Metastases of Urothelial Carcinoma of Urinary Bladder: A Case Report

방광요로상피암에서 드물게 나타나는 피부와 목 림프절로의 전이: 증례 보고

  • Woo Yeol Sim (Department of Radiology, Myongji Hospital, Hanyang University College of Medicine) ;
  • Noh Hyuck Park (Department of Radiology, Myongji Hospital, Hanyang University College of Medicine) ;
  • Yoon Yang Jung (Department of Pathology, Myongji Hospital, Hanyang University College of Medicine)
  • 심우열 (한양대학교 의과대학 명지병원 영상의학과) ;
  • 박노혁 (한양대학교 의과대학 명지병원 영상의학과) ;
  • 정윤양 (한양대학교 의과대학 명지병원 병리과)
  • Received : 2022.05.04
  • Accepted : 2023.01.10
  • Published : 2023.11.01

Abstract

Lymph node metastasis from bladder cancer mainly involves the external/internal iliac and obturator nodes as the primary lymphatic drainage sites of the bladder, and common iliac sites as the secondary drainage. Lymph node involvement above the diaphragm is rare. Metastasis to the head and neck region is associated with poor prognosis and low survival rate. Herein, we report a case of cervical cutaneous and lymph node metastases in a patient with bladder cancer. This is a rare case of advanced urothelial carcinoma presenting as an aggressive inflammatory process with extensive lymph node involvement, without bony or visceral metastasis.

방광암의 림프절 전이는 방광의 림프순환에서 처음과 두 번째로 거쳐 가는 외/내 장골, 폐쇄림프절과 총장골림프절에서 주로 일어난다. 방광암에서 횡격막을 넘어서 일어나는 전이는 드물고, 두경부로의 전이는 예후가 좋지 않으며 생존율도 낮다. 방광요로상피암 환자에서 뼈나 그 외에 고형장기로의 전이 없이 목 피부의 염증성 변화와 함께 림프절전이를 동반하는 것은 드문 증례이므로 이에 보고하고자 한다.

Keywords

References

  1. Antoni S, Ferlay J, Soerjomataram I, Znaor A, Jemal A, Bray F. Bladder cancer incidence and mortality: a global overview and recent trends. Eur Urol 2017;71:96-108
  2. National Institutes of Health. Cancer stat facts: bladder cancer. Bethesda, MD: NIH; 2022. Available at. https://seer.cancer.gov/statfacts/html/urinb.html. Accessed March 3, 2022
  3. Al-Sukhun S, Hussain M. Molecular biology of transitional cell carcinoma. Crit Rev Oncol Hematol 2003;47:181-193
  4. Kancharla VP, Gulmi FA, Agheli A, Degen M, Gohari A, Jiang M, et al. Transitional cell carcinoma of the bladder manifestating as malignant lymphoma with generalized lymphadenopathy. Case Rep Oncol 2010;3:125-130
  5. Cohen DM, Green JG, Diekmann SL, Howell RM, Harn SD. Maxillary metastasis of transitional cell carcinoma: report of a case. Oral Surg Oral Med Oral Pathol 1989;67:185-189
  6. Ferlito A, Shaha AR, Buckley JG, Caruso G, Rinaldo A. Metastatic cervical lymph nodes from urogenital tract carcinoma: a diagnostic and therapeutic challenge. Acta Otolaryngol 2001;121:556-564
  7. MacVicar AD. Bladder cancer staging. BJU Int 2000;86 Suppl 1:111-122
  8. Vikram R, Sandler CM, Ng CS. Imaging and staging of transitional cell carcinoma: part 1, lower urinary tract. AJR Am J Roentgenol 2009;192:1481-1487
  9. Horn T, Zahel T, Adt N, Schmid SC, Heck MM, Thalgott MK, et al. Evaluation of computed tomography for lymph node staging in bladder cancer prior to radical cystectomy. Urol Int 2016;96:51-56
  10. Paner GP, Stadler WM, Hansel DE, Montironi R, Lin DW, Amin MB. Updates in the eighth edition of the tumor-node-metastasis staging classification for urologic cancers. Eur Urol 2018;73:560-569