DOI QR코드

DOI QR Code

MRI Features of Multiple Cranial Neuropathies in Guillain-Barré Syndrome Occurring after COVID-19 Vaccination: A Case Report

COVID-19 백신 접종 후 발생한 길랑-바레증후군에서 보이는 다발성 뇌신경병증의 MRI 소견: 증례 보고

  • Youngsoo Soh (Department of Radiology, Presbyterian Medical Center) ;
  • Eun Ae Yoo (Department of Radiology, Presbyterian Medical Center) ;
  • Eun-Sil Kim (Department of Physical Medicine and Rehabilitation, Presbyterian Medical Center) ;
  • Soo Jung Kim (Department of Radiology, Presbyterian Medical Center)
  • 소영수 (전주예수병원 영상의학과) ;
  • 유은애 (전주예수병원 영상의학과) ;
  • 김은실 (전주예수병원 재활의학과) ;
  • 김수정 (전주예수병원 영상의학과)
  • Received : 2022.06.26
  • Accepted : 2022.11.13
  • Published : 2023.07.01

Abstract

Guillain-Barré syndrome (GBS) is an immune-mediated demyelinating polyneuropathy characterized by progressive, ascending, and symmetrical paralysis. It is known to be triggered by an antecedent infection or vaccination. Recently, GBS development following coronavirus disease 2019 (COVID-19) vaccination has been reported. Cranial neuropathies in typical GBS patients usually involve the facial and the lower cranial nerves (from IX to XII). We report a rare case of multiple cranial neuropathies involving trigeminal, abducens, and facial nerves in a patient who developed GBS following COVID-19 vaccination on the basis of obvious MRI features.

길랑-바레증후군은 면역 매개 탈수초성 다발신경병으로서, 상향 진행성과 좌우 대칭적 마비를 특징으로 하며, 선행 감염이나 예방접종 등에 의해 유발되는 것으로 알려져 있다. 최근 코로나바이러스감염증-19 예방접종 후 길랑-바레증후군 발생이 보고되었다. 길랑-바레증후군에서 보이는 뇌신경병증은 주로 안면신경과 하부뇌신경을 침범한다. 저자들은 코로나바이러스 감염증-19 예방접종 후 발생한 길랑-바레증후군 환자에서 삼차신경, 외전신경, 안면신경을 침범한 다발성 뇌신경병증 사례를 자기공명영상 소견에 기반하여 보고하고자 한다.

Keywords

References

  1. Bhargava A, Banakar BF, Pujar GS, Khichar S. A study of Guillain-Barre syndrome with reference to cranial neuropathy and its prognostic implication. J Neurosci Rural Pract 2014;5(Suppl 1):S43-S47
  2. Caress JB, Castoro RJ, Simmons Z, Scelsa SN, Lewis RA, Ahlawat A, et al. COVID-19-associated Guillain-Barre syndrome: the early pandemic experience. Muscle Nerve 2020;62:485-491
  3. Introna A, Caputo F, Santoro C, Guerra T, Ucci M, Mezzapesa DM, et al. Guillain-Barre syndrome after Astra-Zeneca COVID-19-vaccination: a causal or casual association? Clin Neurol Neurosurg 2021;208:106887
  4. Sarrazin JL, Toulgoat F, Benoudiba F. The lower cranial nerves: IX, X, XI, XII. Diagn Interv Imaging 2013;94:1051-1062
  5. Prasad A, Hurlburt G, Podury S, Tandon M, Kingree S, Sriwastava S. A novel case of bifacial diplegia variant of Guillain-Barre syndrome following Janssen COVID-19 vaccination. Neurol Int 2021;13:404-409
  6. Yoon BA, Bae JS, Kim JK. Recent concepts of Guillain-Barre syndrome. J Korean Neurol Assoc 2019;37:8-19
  7. Maramattom BV, Krishnan P, Paul R, Padmanabhan S, Cherukudal Vishnu Nampoothiri S, Syed AA, et al. Guillain-Barre syndrome following ChAdOx1-S/nCoV-19 vaccine. Ann Neurol 2021;90:312-314
  8. Hutchins KL, Jansen JH, Comer AD, Scheer RV, Zahn GS, Capps AE, et al. COVID-19-associated bifacial weakness with paresthesia subtype of Guillain-Barre syndrome. AJNR Am J Neuroradiol 2020;41:1707-1711
  9. Matarneh AS, Al-Battah AH, Farooqui K, Ghamoodi M, Alhatou M. COVID-19 vaccine causing Guillain-Barre syndrome, a rare potential side effect. Clin Case Rep 2021;9:e04756
  10. Lahoz Fernandez PE, Miranda Pereira J, Fonseca Risso I, Baleeiro Rodrigues Silva P, Freitas Barboza IC, Vieira Silveira CG, et al. Guillain-Barre syndrome following COVID-19 vaccines: a scoping review. Acta Neurol Scand 2022;145:393-398