Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Autonomic dysfunction in multiple sclerosis and neuromyelitis optica spectrum disorder

  • Soonwook Kwon (Department of Neurology, Inha University Hospital) ;
  • Ju-Hong Min (Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 2022.12.12
  • Accepted : 2023.03.20
  • Published : 2023.04.30
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Abstract

Autonomic dysfunction occurs frequently in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). Patients with either condition may present with autonomic symptoms such as bladder, sexual, cardiovascular, thermoregulatory, and gastrointestinal dysfunction, and fatigue, but autonomic symptoms that affect quality of life are underrecognized in clinical practice. The immunopathogenesis of MS has been considered to be associated with autonomic dysfunction. Applying appropriate treatment strategies for autonomic dysfunction is important to improve the quality of life of patients. Here we review autonomic dysfunction and how this is managed in patients with MS and NMOSD.

Keywords

Acknowledgement

This work was supported by an NRF grant funded by the Korea government (no. NRF-2021R1F1A1049347) and by a grant from SMC Research and Development (no. SMO1220511).

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